8S5M
Full-length human cystathionine beta-synthase with C-terminal 6xHis-tag, SAM bound, activated state, helical reconstruction
Summary for 8S5M
Entry DOI | 10.2210/pdb8s5m/pdb |
EMDB information | 19740 |
Descriptor | Cystathionine beta-synthase, S-ADENOSYLMETHIONINE (2 entities in total) |
Functional Keywords | filament, allostery, transferase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 10 |
Total formula weight | 620348.63 |
Authors | |
Primary citation | McCorvie, T.J.,Adamoski, D.,Machado, R.A.C.,Tang, J.,Bailey, H.J.,Ferreira, D.S.M.,Strain-Damerell, C.,Basle, A.,Ambrosio, A.L.B.,Dias, S.M.G.,Yue, W.W. Architecture and regulation of filamentous human cystathionine beta-synthase. Nat Commun, 15:2931-2931, 2024 Cited by PubMed: 38575566DOI: 10.1038/s41467-024-46864-x PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4 Å) |
Structure validation
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