8S5M

Full-length human cystathionine beta-synthase with C-terminal 6xHis-tag, SAM bound, activated state, helical reconstruction

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	Cystathionine beta-synthase	polymer	559	61636.4	10	UniProt (P35520) Pfam (PF00291) Pfam (PF00571)	Homo sapiens (human)	Beta-thionase,Serine sulfhydrase
2	K, L, M, N, O... (A, B, C, D, E...)	S-ADENOSYLMETHIONINE	non-polymer		398.4	10	Chemie (SAM)

Sequence modifications

A, B, C, D, E, F, G, H, I, J: -406 - 144 (UniProt: P35520)

PDB	External Database	Details
Ala 145	-	expression tag
Ala 146	-	expression tag
His 147	-	expression tag
His 148	-	expression tag
His 149	-	expression tag
His 150	-	expression tag
His 151	-	expression tag
His 152	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	10
	Total formula weight	616364.3
Non-Polymers*	Number of molecules	10
	Total formula weight	3984.4
All*	Total formula weight	620348.6

*Water molecules are not included.