8S5M

Full-length human cystathionine beta-synthase with C-terminal 6xHis-tag, SAM bound, activated state, helical reconstruction

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0001958	biological_process	endochondral ossification
A	0001974	biological_process	blood vessel remodeling
A	0003824	molecular_function	catalytic activity
A	0004122	molecular_function	cystathionine beta-synthase activity
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006534	biological_process	cysteine metabolic process
A	0006535	biological_process	cysteine biosynthetic process from serine
A	0006563	biological_process	L-serine metabolic process
A	0006565	biological_process	L-serine catabolic process
A	0006801	biological_process	superoxide metabolic process
A	0008652	biological_process	amino acid biosynthetic process
A	0009069	biological_process	serine family amino acid metabolic process
A	0010749	biological_process	regulation of nitric oxide mediated signal transduction
A	0016829	molecular_function	lyase activity
A	0019343	biological_process	cysteine biosynthetic process via cystathionine
A	0019344	biological_process	cysteine biosynthetic process
A	0019346	biological_process	transsulfuration
A	0019448	biological_process	L-cysteine catabolic process
A	0019825	molecular_function	oxygen binding
A	0019899	molecular_function	enzyme binding
A	0020037	molecular_function	heme binding
A	0021587	biological_process	cerebellum morphogenesis
A	0030170	molecular_function	pyridoxal phosphate binding
A	0031625	molecular_function	ubiquitin protein ligase binding
A	0031667	biological_process	response to nutrient levels
A	0042262	biological_process	DNA protection
A	0042802	molecular_function	identical protein binding
A	0042803	molecular_function	protein homodimerization activity
A	0043066	biological_process	negative regulation of apoptotic process
A	0043418	biological_process	homocysteine catabolic process
A	0044272	biological_process	sulfur compound biosynthetic process
A	0046328	biological_process	regulation of JNK cascade
A	0046872	molecular_function	metal ion binding
A	0050421	molecular_function	nitrite reductase (NO-forming) activity
A	0050667	biological_process	homocysteine metabolic process
A	0051593	biological_process	response to folic acid
A	0060135	biological_process	maternal process involved in female pregnancy
A	0060351	biological_process	cartilage development involved in endochondral bone morphogenesis
A	0070025	molecular_function	carbon monoxide binding
A	0070026	molecular_function	nitric oxide binding
A	0070814	biological_process	hydrogen sulfide biosynthetic process
A	0071456	biological_process	cellular response to hypoxia
A	0072341	molecular_function	modified amino acid binding
A	0097746	biological_process	blood vessel diameter maintenance
A	1904047	molecular_function	S-adenosyl-L-methionine binding
B	0001958	biological_process	endochondral ossification
B	0001974	biological_process	blood vessel remodeling
B	0003824	molecular_function	catalytic activity
B	0004122	molecular_function	cystathionine beta-synthase activity
B	0005515	molecular_function	protein binding
B	0005634	cellular_component	nucleus
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0006534	biological_process	cysteine metabolic process
B	0006535	biological_process	cysteine biosynthetic process from serine
B	0006563	biological_process	L-serine metabolic process
B	0006565	biological_process	L-serine catabolic process
B	0006801	biological_process	superoxide metabolic process
B	0008652	biological_process	amino acid biosynthetic process
B	0009069	biological_process	serine family amino acid metabolic process
B	0010749	biological_process	regulation of nitric oxide mediated signal transduction
B	0016829	molecular_function	lyase activity
B	0019343	biological_process	cysteine biosynthetic process via cystathionine
B	0019344	biological_process	cysteine biosynthetic process
B	0019346	biological_process	transsulfuration
B	0019448	biological_process	L-cysteine catabolic process
B	0019825	molecular_function	oxygen binding
B	0019899	molecular_function	enzyme binding
B	0020037	molecular_function	heme binding
B	0021587	biological_process	cerebellum morphogenesis
B	0030170	molecular_function	pyridoxal phosphate binding
B	0031625	molecular_function	ubiquitin protein ligase binding
B	0031667	biological_process	response to nutrient levels
B	0042262	biological_process	DNA protection
B	0042802	molecular_function	identical protein binding
B	0042803	molecular_function	protein homodimerization activity
B	0043066	biological_process	negative regulation of apoptotic process
B	0043418	biological_process	homocysteine catabolic process
B	0044272	biological_process	sulfur compound biosynthetic process
B	0046328	biological_process	regulation of JNK cascade
B	0046872	molecular_function	metal ion binding
B	0050421	molecular_function	nitrite reductase (NO-forming) activity
B	0050667	biological_process	homocysteine metabolic process
B	0051593	biological_process	response to folic acid
B	0060135	biological_process	maternal process involved in female pregnancy
B	0060351	biological_process	cartilage development involved in endochondral bone morphogenesis
B	0070025	molecular_function	carbon monoxide binding
B	0070026	molecular_function	nitric oxide binding
B	0070814	biological_process	hydrogen sulfide biosynthetic process
B	0071456	biological_process	cellular response to hypoxia
B	0072341	molecular_function	modified amino acid binding
B	0097746	biological_process	blood vessel diameter maintenance
B	1904047	molecular_function	S-adenosyl-L-methionine binding
C	0001958	biological_process	endochondral ossification
C	0001974	biological_process	blood vessel remodeling
C	0003824	molecular_function	catalytic activity
C	0004122	molecular_function	cystathionine beta-synthase activity
C	0005515	molecular_function	protein binding
C	0005634	cellular_component	nucleus
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0006534	biological_process	cysteine metabolic process
C	0006535	biological_process	cysteine biosynthetic process from serine
C	0006563	biological_process	L-serine metabolic process
C	0006565	biological_process	L-serine catabolic process
C	0006801	biological_process	superoxide metabolic process
C	0008652	biological_process	amino acid biosynthetic process
C	0009069	biological_process	serine family amino acid metabolic process
C	0010749	biological_process	regulation of nitric oxide mediated signal transduction
C	0016829	molecular_function	lyase activity
C	0019343	biological_process	cysteine biosynthetic process via cystathionine
C	0019344	biological_process	cysteine biosynthetic process
C	0019346	biological_process	transsulfuration
C	0019448	biological_process	L-cysteine catabolic process
C	0019825	molecular_function	oxygen binding
C	0019899	molecular_function	enzyme binding
C	0020037	molecular_function	heme binding
C	0021587	biological_process	cerebellum morphogenesis
C	0030170	molecular_function	pyridoxal phosphate binding
C	0031625	molecular_function	ubiquitin protein ligase binding
C	0031667	biological_process	response to nutrient levels
C	0042262	biological_process	DNA protection
C	0042802	molecular_function	identical protein binding
C	0042803	molecular_function	protein homodimerization activity
C	0043066	biological_process	negative regulation of apoptotic process
C	0043418	biological_process	homocysteine catabolic process
C	0044272	biological_process	sulfur compound biosynthetic process
C	0046328	biological_process	regulation of JNK cascade
C	0046872	molecular_function	metal ion binding
C	0050421	molecular_function	nitrite reductase (NO-forming) activity
C	0050667	biological_process	homocysteine metabolic process
C	0051593	biological_process	response to folic acid
C	0060135	biological_process	maternal process involved in female pregnancy
C	0060351	biological_process	cartilage development involved in endochondral bone morphogenesis
C	0070025	molecular_function	carbon monoxide binding
C	0070026	molecular_function	nitric oxide binding
C	0070814	biological_process	hydrogen sulfide biosynthetic process
C	0071456	biological_process	cellular response to hypoxia
C	0072341	molecular_function	modified amino acid binding
C	0097746	biological_process	blood vessel diameter maintenance
C	1904047	molecular_function	S-adenosyl-L-methionine binding
D	0001958	biological_process	endochondral ossification
D	0001974	biological_process	blood vessel remodeling
D	0003824	molecular_function	catalytic activity
D	0004122	molecular_function	cystathionine beta-synthase activity
D	0005515	molecular_function	protein binding
D	0005634	cellular_component	nucleus
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0006534	biological_process	cysteine metabolic process
D	0006535	biological_process	cysteine biosynthetic process from serine
D	0006563	biological_process	L-serine metabolic process
D	0006565	biological_process	L-serine catabolic process
D	0006801	biological_process	superoxide metabolic process
D	0008652	biological_process	amino acid biosynthetic process
D	0009069	biological_process	serine family amino acid metabolic process
D	0010749	biological_process	regulation of nitric oxide mediated signal transduction
D	0016829	molecular_function	lyase activity
D	0019343	biological_process	cysteine biosynthetic process via cystathionine
D	0019344	biological_process	cysteine biosynthetic process
D	0019346	biological_process	transsulfuration
D	0019448	biological_process	L-cysteine catabolic process
D	0019825	molecular_function	oxygen binding
D	0019899	molecular_function	enzyme binding
D	0020037	molecular_function	heme binding
D	0021587	biological_process	cerebellum morphogenesis
D	0030170	molecular_function	pyridoxal phosphate binding
D	0031625	molecular_function	ubiquitin protein ligase binding
D	0031667	biological_process	response to nutrient levels
D	0042262	biological_process	DNA protection
D	0042802	molecular_function	identical protein binding
D	0042803	molecular_function	protein homodimerization activity
D	0043066	biological_process	negative regulation of apoptotic process
D	0043418	biological_process	homocysteine catabolic process
D	0044272	biological_process	sulfur compound biosynthetic process
D	0046328	biological_process	regulation of JNK cascade
D	0046872	molecular_function	metal ion binding
D	0050421	molecular_function	nitrite reductase (NO-forming) activity
D	0050667	biological_process	homocysteine metabolic process
D	0051593	biological_process	response to folic acid
D	0060135	biological_process	maternal process involved in female pregnancy
D	0060351	biological_process	cartilage development involved in endochondral bone morphogenesis
D	0070025	molecular_function	carbon monoxide binding
D	0070026	molecular_function	nitric oxide binding
D	0070814	biological_process	hydrogen sulfide biosynthetic process
D	0071456	biological_process	cellular response to hypoxia
D	0072341	molecular_function	modified amino acid binding
D	0097746	biological_process	blood vessel diameter maintenance
D	1904047	molecular_function	S-adenosyl-L-methionine binding
E	0001958	biological_process	endochondral ossification
E	0001974	biological_process	blood vessel remodeling
E	0003824	molecular_function	catalytic activity
E	0004122	molecular_function	cystathionine beta-synthase activity
E	0005515	molecular_function	protein binding
E	0005634	cellular_component	nucleus
E	0005737	cellular_component	cytoplasm
E	0005829	cellular_component	cytosol
E	0006534	biological_process	cysteine metabolic process
E	0006535	biological_process	cysteine biosynthetic process from serine
E	0006563	biological_process	L-serine metabolic process
E	0006565	biological_process	L-serine catabolic process
E	0006801	biological_process	superoxide metabolic process
E	0008652	biological_process	amino acid biosynthetic process
E	0009069	biological_process	serine family amino acid metabolic process
E	0010749	biological_process	regulation of nitric oxide mediated signal transduction
E	0016829	molecular_function	lyase activity
E	0019343	biological_process	cysteine biosynthetic process via cystathionine
E	0019344	biological_process	cysteine biosynthetic process
E	0019346	biological_process	transsulfuration
E	0019448	biological_process	L-cysteine catabolic process
E	0019825	molecular_function	oxygen binding
E	0019899	molecular_function	enzyme binding
E	0020037	molecular_function	heme binding
E	0021587	biological_process	cerebellum morphogenesis
E	0030170	molecular_function	pyridoxal phosphate binding
E	0031625	molecular_function	ubiquitin protein ligase binding
E	0031667	biological_process	response to nutrient levels
E	0042262	biological_process	DNA protection
E	0042802	molecular_function	identical protein binding
E	0042803	molecular_function	protein homodimerization activity
E	0043066	biological_process	negative regulation of apoptotic process
E	0043418	biological_process	homocysteine catabolic process
E	0044272	biological_process	sulfur compound biosynthetic process
E	0046328	biological_process	regulation of JNK cascade
E	0046872	molecular_function	metal ion binding
E	0050421	molecular_function	nitrite reductase (NO-forming) activity
E	0050667	biological_process	homocysteine metabolic process
E	0051593	biological_process	response to folic acid
E	0060135	biological_process	maternal process involved in female pregnancy
E	0060351	biological_process	cartilage development involved in endochondral bone morphogenesis
E	0070025	molecular_function	carbon monoxide binding
E	0070026	molecular_function	nitric oxide binding
E	0070814	biological_process	hydrogen sulfide biosynthetic process
E	0071456	biological_process	cellular response to hypoxia
E	0072341	molecular_function	modified amino acid binding
E	0097746	biological_process	blood vessel diameter maintenance
E	1904047	molecular_function	S-adenosyl-L-methionine binding
F	0001958	biological_process	endochondral ossification
F	0001974	biological_process	blood vessel remodeling
F	0003824	molecular_function	catalytic activity
F	0004122	molecular_function	cystathionine beta-synthase activity
F	0005515	molecular_function	protein binding
F	0005634	cellular_component	nucleus
F	0005737	cellular_component	cytoplasm
F	0005829	cellular_component	cytosol
F	0006534	biological_process	cysteine metabolic process
F	0006535	biological_process	cysteine biosynthetic process from serine
F	0006563	biological_process	L-serine metabolic process
F	0006565	biological_process	L-serine catabolic process
F	0006801	biological_process	superoxide metabolic process
F	0008652	biological_process	amino acid biosynthetic process
F	0009069	biological_process	serine family amino acid metabolic process
F	0010749	biological_process	regulation of nitric oxide mediated signal transduction
F	0016829	molecular_function	lyase activity
F	0019343	biological_process	cysteine biosynthetic process via cystathionine
F	0019344	biological_process	cysteine biosynthetic process
F	0019346	biological_process	transsulfuration
F	0019448	biological_process	L-cysteine catabolic process
F	0019825	molecular_function	oxygen binding
F	0019899	molecular_function	enzyme binding
F	0020037	molecular_function	heme binding
F	0021587	biological_process	cerebellum morphogenesis
F	0030170	molecular_function	pyridoxal phosphate binding
F	0031625	molecular_function	ubiquitin protein ligase binding
F	0031667	biological_process	response to nutrient levels
F	0042262	biological_process	DNA protection
F	0042802	molecular_function	identical protein binding
F	0042803	molecular_function	protein homodimerization activity
F	0043066	biological_process	negative regulation of apoptotic process
F	0043418	biological_process	homocysteine catabolic process
F	0044272	biological_process	sulfur compound biosynthetic process
F	0046328	biological_process	regulation of JNK cascade
F	0046872	molecular_function	metal ion binding
F	0050421	molecular_function	nitrite reductase (NO-forming) activity
F	0050667	biological_process	homocysteine metabolic process
F	0051593	biological_process	response to folic acid
F	0060135	biological_process	maternal process involved in female pregnancy
F	0060351	biological_process	cartilage development involved in endochondral bone morphogenesis
F	0070025	molecular_function	carbon monoxide binding
F	0070026	molecular_function	nitric oxide binding
F	0070814	biological_process	hydrogen sulfide biosynthetic process
F	0071456	biological_process	cellular response to hypoxia
F	0072341	molecular_function	modified amino acid binding
F	0097746	biological_process	blood vessel diameter maintenance
F	1904047	molecular_function	S-adenosyl-L-methionine binding
G	0001958	biological_process	endochondral ossification
G	0001974	biological_process	blood vessel remodeling
G	0003824	molecular_function	catalytic activity
G	0004122	molecular_function	cystathionine beta-synthase activity
G	0005515	molecular_function	protein binding
G	0005634	cellular_component	nucleus
G	0005737	cellular_component	cytoplasm
G	0005829	cellular_component	cytosol
G	0006534	biological_process	cysteine metabolic process
G	0006535	biological_process	cysteine biosynthetic process from serine
G	0006563	biological_process	L-serine metabolic process
G	0006565	biological_process	L-serine catabolic process
G	0006801	biological_process	superoxide metabolic process
G	0008652	biological_process	amino acid biosynthetic process
G	0009069	biological_process	serine family amino acid metabolic process
G	0010749	biological_process	regulation of nitric oxide mediated signal transduction
G	0016829	molecular_function	lyase activity
G	0019343	biological_process	cysteine biosynthetic process via cystathionine
G	0019344	biological_process	cysteine biosynthetic process
G	0019346	biological_process	transsulfuration
G	0019448	biological_process	L-cysteine catabolic process
G	0019825	molecular_function	oxygen binding
G	0019899	molecular_function	enzyme binding
G	0020037	molecular_function	heme binding
G	0021587	biological_process	cerebellum morphogenesis
G	0030170	molecular_function	pyridoxal phosphate binding
G	0031625	molecular_function	ubiquitin protein ligase binding
G	0031667	biological_process	response to nutrient levels
G	0042262	biological_process	DNA protection
G	0042802	molecular_function	identical protein binding
G	0042803	molecular_function	protein homodimerization activity
G	0043066	biological_process	negative regulation of apoptotic process
G	0043418	biological_process	homocysteine catabolic process
G	0044272	biological_process	sulfur compound biosynthetic process
G	0046328	biological_process	regulation of JNK cascade
G	0046872	molecular_function	metal ion binding
G	0050421	molecular_function	nitrite reductase (NO-forming) activity
G	0050667	biological_process	homocysteine metabolic process
G	0051593	biological_process	response to folic acid
G	0060135	biological_process	maternal process involved in female pregnancy
G	0060351	biological_process	cartilage development involved in endochondral bone morphogenesis
G	0070025	molecular_function	carbon monoxide binding
G	0070026	molecular_function	nitric oxide binding
G	0070814	biological_process	hydrogen sulfide biosynthetic process
G	0071456	biological_process	cellular response to hypoxia
G	0072341	molecular_function	modified amino acid binding
G	0097746	biological_process	blood vessel diameter maintenance
G	1904047	molecular_function	S-adenosyl-L-methionine binding
H	0001958	biological_process	endochondral ossification
H	0001974	biological_process	blood vessel remodeling
H	0003824	molecular_function	catalytic activity
H	0004122	molecular_function	cystathionine beta-synthase activity
H	0005515	molecular_function	protein binding
H	0005634	cellular_component	nucleus
H	0005737	cellular_component	cytoplasm
H	0005829	cellular_component	cytosol
H	0006534	biological_process	cysteine metabolic process
H	0006535	biological_process	cysteine biosynthetic process from serine
H	0006563	biological_process	L-serine metabolic process
H	0006565	biological_process	L-serine catabolic process
H	0006801	biological_process	superoxide metabolic process
H	0008652	biological_process	amino acid biosynthetic process
H	0009069	biological_process	serine family amino acid metabolic process
H	0010749	biological_process	regulation of nitric oxide mediated signal transduction
H	0016829	molecular_function	lyase activity
H	0019343	biological_process	cysteine biosynthetic process via cystathionine
H	0019344	biological_process	cysteine biosynthetic process
H	0019346	biological_process	transsulfuration
H	0019448	biological_process	L-cysteine catabolic process
H	0019825	molecular_function	oxygen binding
H	0019899	molecular_function	enzyme binding
H	0020037	molecular_function	heme binding
H	0021587	biological_process	cerebellum morphogenesis
H	0030170	molecular_function	pyridoxal phosphate binding
H	0031625	molecular_function	ubiquitin protein ligase binding
H	0031667	biological_process	response to nutrient levels
H	0042262	biological_process	DNA protection
H	0042802	molecular_function	identical protein binding
H	0042803	molecular_function	protein homodimerization activity
H	0043066	biological_process	negative regulation of apoptotic process
H	0043418	biological_process	homocysteine catabolic process
H	0044272	biological_process	sulfur compound biosynthetic process
H	0046328	biological_process	regulation of JNK cascade
H	0046872	molecular_function	metal ion binding
H	0050421	molecular_function	nitrite reductase (NO-forming) activity
H	0050667	biological_process	homocysteine metabolic process
H	0051593	biological_process	response to folic acid
H	0060135	biological_process	maternal process involved in female pregnancy
H	0060351	biological_process	cartilage development involved in endochondral bone morphogenesis
H	0070025	molecular_function	carbon monoxide binding
H	0070026	molecular_function	nitric oxide binding
H	0070814	biological_process	hydrogen sulfide biosynthetic process
H	0071456	biological_process	cellular response to hypoxia
H	0072341	molecular_function	modified amino acid binding
H	0097746	biological_process	blood vessel diameter maintenance
H	1904047	molecular_function	S-adenosyl-L-methionine binding
I	0001958	biological_process	endochondral ossification
I	0001974	biological_process	blood vessel remodeling
I	0003824	molecular_function	catalytic activity
I	0004122	molecular_function	cystathionine beta-synthase activity
I	0005515	molecular_function	protein binding
I	0005634	cellular_component	nucleus
I	0005737	cellular_component	cytoplasm
I	0005829	cellular_component	cytosol
I	0006534	biological_process	cysteine metabolic process
I	0006535	biological_process	cysteine biosynthetic process from serine
I	0006563	biological_process	L-serine metabolic process
I	0006565	biological_process	L-serine catabolic process
I	0006801	biological_process	superoxide metabolic process
I	0008652	biological_process	amino acid biosynthetic process
I	0009069	biological_process	serine family amino acid metabolic process
I	0010749	biological_process	regulation of nitric oxide mediated signal transduction
I	0016829	molecular_function	lyase activity
I	0019343	biological_process	cysteine biosynthetic process via cystathionine
I	0019344	biological_process	cysteine biosynthetic process
I	0019346	biological_process	transsulfuration
I	0019448	biological_process	L-cysteine catabolic process
I	0019825	molecular_function	oxygen binding
I	0019899	molecular_function	enzyme binding
I	0020037	molecular_function	heme binding
I	0021587	biological_process	cerebellum morphogenesis
I	0030170	molecular_function	pyridoxal phosphate binding
I	0031625	molecular_function	ubiquitin protein ligase binding
I	0031667	biological_process	response to nutrient levels
I	0042262	biological_process	DNA protection
I	0042802	molecular_function	identical protein binding
I	0042803	molecular_function	protein homodimerization activity
I	0043066	biological_process	negative regulation of apoptotic process
I	0043418	biological_process	homocysteine catabolic process
I	0044272	biological_process	sulfur compound biosynthetic process
I	0046328	biological_process	regulation of JNK cascade
I	0046872	molecular_function	metal ion binding
I	0050421	molecular_function	nitrite reductase (NO-forming) activity
I	0050667	biological_process	homocysteine metabolic process
I	0051593	biological_process	response to folic acid
I	0060135	biological_process	maternal process involved in female pregnancy
I	0060351	biological_process	cartilage development involved in endochondral bone morphogenesis
I	0070025	molecular_function	carbon monoxide binding
I	0070026	molecular_function	nitric oxide binding
I	0070814	biological_process	hydrogen sulfide biosynthetic process
I	0071456	biological_process	cellular response to hypoxia
I	0072341	molecular_function	modified amino acid binding
I	0097746	biological_process	blood vessel diameter maintenance
I	1904047	molecular_function	S-adenosyl-L-methionine binding
J	0001958	biological_process	endochondral ossification
J	0001974	biological_process	blood vessel remodeling
J	0003824	molecular_function	catalytic activity
J	0004122	molecular_function	cystathionine beta-synthase activity
J	0005515	molecular_function	protein binding
J	0005634	cellular_component	nucleus
J	0005737	cellular_component	cytoplasm
J	0005829	cellular_component	cytosol
J	0006534	biological_process	cysteine metabolic process
J	0006535	biological_process	cysteine biosynthetic process from serine
J	0006563	biological_process	L-serine metabolic process
J	0006565	biological_process	L-serine catabolic process
J	0006801	biological_process	superoxide metabolic process
J	0008652	biological_process	amino acid biosynthetic process
J	0009069	biological_process	serine family amino acid metabolic process
J	0010749	biological_process	regulation of nitric oxide mediated signal transduction
J	0016829	molecular_function	lyase activity
J	0019343	biological_process	cysteine biosynthetic process via cystathionine
J	0019344	biological_process	cysteine biosynthetic process
J	0019346	biological_process	transsulfuration
J	0019448	biological_process	L-cysteine catabolic process
J	0019825	molecular_function	oxygen binding
J	0019899	molecular_function	enzyme binding
J	0020037	molecular_function	heme binding
J	0021587	biological_process	cerebellum morphogenesis
J	0030170	molecular_function	pyridoxal phosphate binding
J	0031625	molecular_function	ubiquitin protein ligase binding
J	0031667	biological_process	response to nutrient levels
J	0042262	biological_process	DNA protection
J	0042802	molecular_function	identical protein binding
J	0042803	molecular_function	protein homodimerization activity
J	0043066	biological_process	negative regulation of apoptotic process
J	0043418	biological_process	homocysteine catabolic process
J	0044272	biological_process	sulfur compound biosynthetic process
J	0046328	biological_process	regulation of JNK cascade
J	0046872	molecular_function	metal ion binding
J	0050421	molecular_function	nitrite reductase (NO-forming) activity
J	0050667	biological_process	homocysteine metabolic process
J	0051593	biological_process	response to folic acid
J	0060135	biological_process	maternal process involved in female pregnancy
J	0060351	biological_process	cartilage development involved in endochondral bone morphogenesis
J	0070025	molecular_function	carbon monoxide binding
J	0070026	molecular_function	nitric oxide binding
J	0070814	biological_process	hydrogen sulfide biosynthetic process
J	0071456	biological_process	cellular response to hypoxia
J	0072341	molecular_function	modified amino acid binding
J	0097746	biological_process	blood vessel diameter maintenance
J	1904047	molecular_function	S-adenosyl-L-methionine binding

Functional Information from PROSITE/UniProt

site_id	PS00901
Number of Residues	19
Details	CYS_SYNTHASE Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. KcEffn.AGgSVKdRiSlrM

Chain	Residue	Details
A	LYS-299-MET-281

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	20
Details	BINDING: axial binding residue => ECO:0000269|PubMed:11483494, ECO:0000269|PubMed:12173932

Chain	Residue	Details
A	CYS-355
E	HIS-342
F	CYS-355
F	HIS-342
G	CYS-355
G	HIS-342
H	CYS-355
H	HIS-342
I	CYS-355
I	HIS-342
J	CYS-355
A	HIS-342
J	HIS-342
B	CYS-355
B	HIS-342
C	CYS-355
C	HIS-342
D	CYS-355
D	HIS-342
E	CYS-355

---

site_id	SWS_FT_FI2
Number of Residues	30
Details	BINDING: BINDING => ECO:0000269|PubMed:11483494, ECO:0000269|PubMed:12173932

Chain	Residue	Details
A	ASN-258
D	ASN-258
D	GLY-151
D	SER-58
E	ASN-258
E	GLY-151
E	SER-58
F	ASN-258
F	GLY-151
F	SER-58
G	ASN-258
A	GLY-151
G	GLY-151
G	SER-58
H	ASN-258
H	GLY-151
H	SER-58
I	ASN-258
I	GLY-151
I	SER-58
J	ASN-258
J	GLY-151
A	SER-58
J	SER-58
B	ASN-258
B	GLY-151
B	SER-58
C	ASN-258
C	GLY-151
C	SER-58

---

site_id	SWS_FT_FI3
Number of Residues	10
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:21406692

Chain	Residue	Details
A	SER-380
J	SER-380
B	SER-380
C	SER-380
D	SER-380
E	SER-380
F	SER-380
G	SER-380
H	SER-380
I	SER-380

---

site_id	SWS_FT_FI4
Number of Residues	10
Details	MOD_RES: N6-(pyridoxal phosphate)lysine => ECO:0000269|PubMed:11483494, ECO:0000269|PubMed:12173932

Chain	Residue	Details
A	LYS-288
J	LYS-288
B	LYS-288
C	LYS-288
D	LYS-288
E	LYS-288
F	LYS-288
G	LYS-288
H	LYS-288
I	LYS-288

---

site_id	SWS_FT_FI5
Number of Residues	10
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163

Chain	Residue	Details
A	SER-208
J	SER-208
B	SER-208
C	SER-208
D	SER-208
E	SER-208
F	SER-208
G	SER-208
H	SER-208
I	SER-208

---

site_id	SWS_FT_FI6
Number of Residues	20
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO) => ECO:0000269|PubMed:17087506

Chain	Residue	Details
A	LYS-196
F	LYS-196
G	LYS-196
H	LYS-196
I	LYS-196
J	LYS-196
B	LYS-196
C	LYS-196
D	LYS-196
E	LYS-196

---

Catalytic Information from CSA

site_id	MCSA1
Number of Residues
Details	M-CSA 713

Chain

Residue

Details

---

site_id	MCSA10
Number of Residues
Details	M-CSA 713

Chain

Residue

Details

---

site_id	MCSA2
Number of Residues
Details	M-CSA 713

Chain

Residue

Details

---

site_id	MCSA3
Number of Residues
Details	M-CSA 713

Chain

Residue

Details

---

site_id	MCSA4
Number of Residues
Details	M-CSA 713

Chain

Residue

Details

---

site_id	MCSA5
Number of Residues
Details	M-CSA 713

Chain

Residue

Details

---

site_id	MCSA6
Number of Residues
Details	M-CSA 713

Chain

Residue

Details

---

site_id	MCSA7
Number of Residues
Details	M-CSA 713

Chain

Residue

Details

---

site_id	MCSA8
Number of Residues
Details	M-CSA 713

Chain

Residue

Details

---

site_id	MCSA9
Number of Residues
Details	M-CSA 713

Chain

Residue

Details

---