4LYI

Crystal Structure of apo-BRD4(1)

Summary for 4LYI

Entry DOI	10.2210/pdb4lyi/pdb
Related	4LYS 4LYW 4LZR 4LZS
Descriptor	Bromodomain-containing protein 4, 1,2-ETHANEDIOL, IODIDE ION, ... (6 entities in total)
Functional Keywords	bromodomain, epigenetic reader protein, acetylated lysin, histone tail, nucleus, protein binding
Biological source	Homo sapiens (human)
Cellular location	Nucleus: O60885
Total number of polymer chains	1
Total formula weight	15948.02
Authors	Wohlwend, D. (deposition date: 2013-07-31, release date: 2014-01-15, Last modification date: 2024-02-28)
Primary citation	Lucas, X.,Wohlwend, D.,Hugle, M.,Schmidtkunz, K.,Gerhardt, S.,Schule, R.,Jung, M.,Einsle, O.,Gunther, S. 4-Acyl pyrroles: mimicking acetylated lysines in histone code reading. Angew.Chem.Int.Ed.Engl., 52:14055-14059, 2013 Cited by PubMed: 24272870 DOI: 10.1002/anie.201307652 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.3 Å)

Structure validation