1T2E
| Plasmodium falciparum lactate dehydrogenase S245A, A327P mutant complexed with NADH and oxamate | Descriptor: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, GLYCEROL, L-lactate dehydrogenase, ... | Authors: | Cameron, A, Read, J, Tranter, R, Winter, V.J, Sessions, R.B, Brady, R.L, Vivas, L, Easton, A, Kendrick, H, Croft, S.L, Barros, D, Lavandera, J.L, Martin, J.J, Risco, F, Garcia-Ochoa, S, Gamo, F.J, Sanz, L, Leon, L, Ruiz, J.R, Gabarro, R, Mallo, A, De Las Heras, F.G. | Deposit date: | 2004-04-21 | Release date: | 2004-05-11 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Identification and Activity of a Series of Azole-based Compounds with Lactate Dehydrogenase-directed Anti-malarial Activity. J.Biol.Chem., 279, 2004
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1T2F
| Human B lactate dehydrogenase complexed with NAD+ and 4-hydroxy-1,2,5-oxadiazole-3-carboxylic acid | Descriptor: | 4-HYDROXY-1,2,5-OXADIAZOLE-3-CARBOXYLIC ACID, L-lactate dehydrogenase B chain, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | Authors: | Cameron, A, Read, J, Tranter, R, Winter, V.J, Sessions, R.B, Brady, R.L, Vivas, L, Easton, A, Kendrick, H, Croft, S.L, Barros, D, Lavandera, J.L, Martin, J.J, Risco, F, Garcia-Ochoa, S, Gamo, F.J, Sanz, L, Leon, L, Ruiz, J.R, Gabarro, R, Mallo, A, De Las Heras, F.G. | Deposit date: | 2004-04-21 | Release date: | 2004-05-11 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Identification and Activity of a Series of Azole-based Compounds with Lactate Dehydrogenase-directed Anti-malarial Activity. J.Biol.Chem., 279, 2004
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1T2H
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1T2I
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1T2J
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1T2K
| Structure Of The DNA Binding Domains Of IRF3, ATF-2 and Jun Bound To DNA | Descriptor: | 31-MER, Cyclic-AMP-dependent transcription factor ATF-2, Interferon regulatory factor 3, ... | Authors: | Panne, D, Maniatis, T, Harrison, S.C. | Deposit date: | 2004-04-21 | Release date: | 2004-11-16 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Crystal structure of ATF-2/c-Jun and IRF-3 bound to the interferon-beta enhancer. Embo J., 23, 2004
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1T2L
| Three Crystal Structures of Human Coactosin-like Protein | Descriptor: | Coactosin-like protein | Authors: | Liu, L, Wei, Z, Chen, Z, Wang, Y, Gong, W. | Deposit date: | 2004-04-22 | Release date: | 2004-11-23 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal Structure of Human Coactosin-like Protein J.Mol.Biol., 344, 2004
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1T2M
| Solution Structure Of The Pdz Domain Of AF-6 | Descriptor: | AF-6 protein | Authors: | Zhou, H, Wu, J.H, Xu, Y.Q, Huang, A.D, Shi, Y.Y. | Deposit date: | 2004-04-22 | Release date: | 2005-02-08 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution Structure of AF-6 PDZ Domain and Its Interaction with the C-terminal Peptides from Neurexin and Bcr J.Biol.Chem., 280, 2005
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1T2N
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1T2O
| Crystal structure of Se-SrtA, C184-Ala | Descriptor: | sortase | Authors: | Zong, Y, Bice, T.W, Ton-That, H, Schneewind, O, Narayana, S.V. | Deposit date: | 2004-04-22 | Release date: | 2004-09-07 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structures of Staphylococcus aureus sortase A and its substrate complex J.Biol.Chem., 279, 2004
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1T2P
| Crystal structure of Sortase A from Staphylococcus aureus | Descriptor: | sortase | Authors: | Zong, Y, Bice, T.W, Ton-That, H, Schneewind, O, Narayana, S.V. | Deposit date: | 2004-04-22 | Release date: | 2004-09-07 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | CRYSTAL STRUCTURES OF STAPHYLOCOCCUS AUREUS SORTASE A AND ITS SUBSTRATE COMPLEX J.Biol.Chem., 279, 2004
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1T2Q
| The Crystal Structure of an NNA7 Fab that recognizes an N-type blood group antigen | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Fab NNA7 Heavy Chain, Fab NNA7 Light Chain, ... | Authors: | Xie, K, Song, S.C, Spitalnik, S.L, Wedekind, J.E. | Deposit date: | 2004-04-22 | Release date: | 2005-06-07 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.83 Å) | Cite: | Crystal Structure and Mutational Analysis of an Antibody that Recognizes an N-type Blood Group Antigen To be Published
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1T2R
| Structural basis for 3' end recognition of nucleic acids by the Drosophila Argonaute 2 PAZ domain | Descriptor: | 5'-R(*CP*UP*CP*AP*C)-3', Argonaute 2 | Authors: | Lingel, A, Simon, B, Izaurralde, E, Sattler, M. | Deposit date: | 2004-04-22 | Release date: | 2004-06-01 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Nucleic acid 3'-end recognition by the Argonaute2 PAZ domain. Nat.Struct.Mol.Biol., 11, 2004
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1T2S
| Structural basis for 3' end recognition of nucleic acids by the Drosophila Argonaute 2 PAZ domain | Descriptor: | 5'-D(*CP*TP*CP*AP*C)-3', Argonaute 2 | Authors: | Lingel, A, Simon, B, Izaurralde, E, Sattler, M. | Deposit date: | 2004-04-22 | Release date: | 2004-06-01 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Nucleic acid 3'-end recognition by the Argonaute2 PAZ domain. Nat.Struct.Mol.Biol., 11, 2004
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1T2T
| Crystal structure of the DNA-binding domain of intron endonuclease I-TevI with operator site | Descriptor: | 5'-D(*AP*AP*TP*TP*AP*AP*AP*GP*GP*GP*CP*AP*GP*TP*CP*CP*TP*AP*CP*AP*A)-3', 5'-D(*TP*TP*TP*GP*TP*AP*GP*GP*AP*CP*TP*GP*CP*CP*CP*TP*TP*TP*AP*AP*T)-3', Intron-associated endonuclease 1, ... | Authors: | Edgell, D.R, Derbyshire, V, Van Roey, P, LaBonne, S, Stanger, M.J, Li, Z, Boyd, T.M, Shub, D.A, Belfort, M. | Deposit date: | 2004-04-22 | Release date: | 2004-09-07 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Intron-encoded homing endonuclease I-TevI also functions as a transcriptional autorepressor. Nat.Struct.Mol.Biol., 11, 2004
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1T2U
| Structural basis of phosphopeptide recognition by the BRCT domain of BRCA1: structure of BRCA1 missense variant V1809F | Descriptor: | Breast cancer type 1 susceptibility protein, COBALT (II) ION, SULFATE ION | Authors: | Williams, R.S, Lee, M.S, Duong, D.D, Glover, J.N.M. | Deposit date: | 2004-04-22 | Release date: | 2004-05-11 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural Basis of Phosphopeptide recognition by the BRCT domain of BRCA1 Nat.Struct.Mol.Biol., 11, 2004
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1T2V
| Structural basis of phospho-peptide recognition by the BRCT domain of BRCA1, structure with phosphopeptide | Descriptor: | BRCTide-7PS, Breast cancer type 1 susceptibility protein | Authors: | Williams, R.S, Lee, M.S, Hau, D.D, Glover, J.N.M. | Deposit date: | 2004-04-22 | Release date: | 2004-05-11 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Structural basis of phosphopeptide recognition by the BRCT domain of BRCA1 Nat.Struct.Mol.Biol., 11, 2004
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1T2W
| Crystal Structure of Sortase A in Complex with a LPETG peptide | Descriptor: | Class A sortase SrtA, Peptide LEU-PRO-GLU-THR-GLY | Authors: | Zong, Y, Bice, T.W, Ton-That, H, Schneewind, O, Narayana, S.V. | Deposit date: | 2004-04-23 | Release date: | 2004-09-07 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of Staphylococcus aureus sortase A and its substrate complex J.Biol.Chem., 279, 2004
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1T2X
| Glactose oxidase C383S mutant identified by directed evolution | Descriptor: | ACETATE ION, COPPER (II) ION, Galactose Oxidase, ... | Authors: | Wilkinson, D, Akumanyi, N, Hurtado-Guerrero, R, Dawkes, H, Knowles, P.F, Phillips, S.E.V, McPherson, M.J. | Deposit date: | 2004-04-23 | Release date: | 2004-05-18 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural and kinetic studies of a series of mutants of galactose oxidase identified by directed evolution. Protein Eng.Des.Sel., 17, 2004
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1T2Y
| NMR solution structure of the protein part of Cu6-Neurospora crassa MT | Descriptor: | Metallothionein | Authors: | Cobine, P.A, McKay, R.T, Zangger, K, Dameron, C.T, Armitage, I.M. | Deposit date: | 2004-04-23 | Release date: | 2004-11-23 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution structure of Cu metallothionein from the fungus Neurospora crassa Eur.J.Biochem., 271, 2004
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1T31
| A Dual Inhibitor of the Leukocyte Proteases Cathepsin G and Chymase with Therapeutic Efficacy in Animals Models of Inflammation | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-[3-({METHYL[1-(2-NAPHTHOYL)PIPERIDIN-4-YL]AMINO}CARBONYL)-2-NAPHTHYL]-1-(1-NAPHTHYL)-2-OXOETHYLPHOSPHONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | de Garavilla, L, Greco, M.N, Giardino, E.C, Wells, G.I, Haertlein, B.J, Kauffman, J.A, Corcoran, T.W, Derian, C.K, Eckardt, A.J, Abraham, W.M, Sukumar, N, Chen, Z, Pineda, A.O, Mathews, F.S, Di Cera, E, Andrade-Gordon, P, Damiano, B.P, Maryanoff, B.E, Pereira, P.J.B, Wang, Z.M, Rubin, H, Huber, R, Bode, W, Schechter, N.M, Strobl, S. | Deposit date: | 2004-04-23 | Release date: | 2005-03-01 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | A novel, potent dual inhibitor of the leukocyte proteases cathepsin G and chymase: molecular mechanisms and anti-inflammatory activity in vivo. J.Biol.Chem., 280, 2005
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1T32
| A Dual Inhibitor of the Leukocyte Proteases Cathepsin G and Chymase with Therapeutic Efficacy in Animals Models of Inflammation | Descriptor: | 2-[3-({METHYL[1-(2-NAPHTHOYL)PIPERIDIN-4-YL]AMINO}CARBONYL)-2-NAPHTHYL]-1-(1-NAPHTHYL)-2-OXOETHYLPHOSPHONIC ACID, Cathepsin G, SULFATE ION | Authors: | de Garavilla, L, Greco, M.N, Giardino, E.C, Wells, G.I, Haertlein, B.J, Kauffman, J.A, Corcoran, T.W, Derian, C.K, Eckardt, A.J, Abraham, W.M, Sukumar, N, Chen, Z, Pineda, A.O, Mathews, F.S, Di Cera, E, Andrade-Gordon, P, Damiano, B.P, Maryanoff, B.E. | Deposit date: | 2004-04-23 | Release date: | 2005-03-01 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | A novel, potent dual inhibitor of the leukocyte proteases cathepsin G and chymase: molecular mechanisms and anti-inflammatory activity in vivo. J.Biol.Chem., 280, 2005
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1T33
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1T34
| ROTATION MECHANISM FOR TRANSMEMBRANE SIGNALING BY THE ATRIAL NATRIURETIC PEPTIDE RECEPTOR | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Atrial natriuretic peptide factor, Atrial natriuretic peptide receptor A, ... | Authors: | Ogawa, H, Qiu, Y, Ogata, C.M, Misono, K.S. | Deposit date: | 2004-04-23 | Release date: | 2004-08-03 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Crystal structure of hormone-bound atrial natriuretic peptide receptor extracellular domain: rotation mechanism for transmembrane signal transduction J.Biol.Chem., 279, 2004
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1T35
| CRYSTAL STRUCTURE OF A HYPOTHETICAL PROTEIN YVDD- A PUTATIVE LYSINE DECARBOXYLASE | Descriptor: | HYPOTHETICAL PROTEIN YVDD, Putative Lysine Decarboxylase, SULFATE ION | Authors: | Rajashankar, K.R, Kniewel, R, Solorzano, V, Lima, C.D, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2004-04-23 | Release date: | 2004-05-04 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.72 Å) | Cite: | Crystal Structure of a Hypothetical Protein Yvdd - Putative Lysine Decarboxylase To be Published
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