1T2T

Crystal structure of the DNA-binding domain of intron endonuclease I-TevI with operator site

Summary for 1T2T

• Entry DOI: 10.2210/pdb1t2t/pdb
• Related: 1I3J
• Descriptor: 5'-D(*TP*TP*TP*GP*TP*AP*GP*GP*AP*CP*TP*GP*CP*CP*CP*TP*TP*TP*AP*AP*T)-3', 5'-D(*AP*AP*TP*TP*AP*AP*AP*GP*GP*GP*CP*AP*GP*TP*CP*CP*TP*AP*CP*AP*A)-3', Intron-associated endonuclease 1, ... (5 entities in total)
• Functional Keywords: protein-dna complex, hydrolase-dna complex, hydrolase/dna
• Biological source: Enterobacteria phage T4
• Total number of polymer chains: 3
• Total formula weight: 26191.01

Authors

Edgell, D.R.,Derbyshire, V.,Van Roey, P.,LaBonne, S.,Stanger, M.J.,Li, Z.,Boyd, T.M.,Shub, D.A.,Belfort, M. (deposition date: 2004-04-22, release date: 2004-09-07, Last modification date: 2023-08-23)

• Primary citation: Edgell, D.R.,Derbyshire, V.,Van Roey, P.,LaBonne, S.,Stanger, M.J.,Li, Z.,Boyd, T.M.,Shub, D.A.,Belfort, M.; Intron-encoded homing endonuclease I-TevI also functions as a transcriptional autorepressor.; Nat.Struct.Mol.Biol., 11:936-944, 2004; PubMed: 15361856; DOI: 10.1038/nsmb823

Experimental method

X-RAY DIFFRACTION (2.5 Å)