1T2U

Structural basis of phosphopeptide recognition by the BRCT domain of BRCA1: structure of BRCA1 missense variant V1809F

Summary for 1T2U

Entry DOI	10.2210/pdb1t2u/pdb
Related	1JNX 1N5O 1T2V
Descriptor	Breast cancer type 1 susceptibility protein, COBALT (II) ION, SULFATE ION, ... (4 entities in total)
Functional Keywords	brca1, brct, phospho-peptide, missense mutation, antitumor protein
Biological source	Homo sapiens (human)
Cellular location	Nucleus. Isoform 3: Cytoplasm. Isoform 5: Cytoplasm: P38398
Total number of polymer chains	1
Total formula weight	24830.34
Authors	Williams, R.S.,Lee, M.S.,Duong, D.D.,Glover, J.N.M. (deposition date: 2004-04-22, release date: 2004-05-11, Last modification date: 2024-02-14)
Primary citation	Williams, R.S.,Lee, M.S.,Duong, D.D.,Glover, J.N.M. Structural Basis of Phosphopeptide recognition by the BRCT domain of BRCA1 Nat.Struct.Mol.Biol., 11:519-525, 2004 Cited by PubMed: 15133503 DOI: 10.1038/nsmb776 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.8 Å)

Structure validation