1T2U
Structural basis of phosphopeptide recognition by the BRCT domain of BRCA1: structure of BRCA1 missense variant V1809F
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Breast cancer type 1 susceptibility protein | polymer | 214 | 24579.3 | 1 | UniProt (P38398) Pfam (PF00533) | Homo sapiens (human) | |
| 2 | B (A) | COBALT (II) ION | non-polymer | 58.9 | 1 | Chemie (CO) | |||
| 3 | C, D (A) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 4 | E (A) | water | water | 18.0 | 51 | Chemie (HOH) |
Sequence modifications
A: 1646 - 1859 (UniProt: P38398)
| PDB | External Database | Details |
|---|---|---|
| Phe 1809 | Val 1809 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 24579.3 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 251.1 | |
| All* | Total formula weight | 24830.3 |






