1T2V
Structural basis of phospho-peptide recognition by the BRCT domain of BRCA1, structure with phosphopeptide
Summary for 1T2V
Entry DOI | 10.2210/pdb1t2v/pdb |
Related | 1JNX 1N5O 1T2U |
Descriptor | Breast cancer type 1 susceptibility protein, BRCTide-7PS (2 entities in total) |
Functional Keywords | brct, brca1, breast cancer, cell signaling, missense mutation, phosphopeptide, antitumor protein |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus. Isoform 3: Cytoplasm. Isoform 5: Cytoplasm: P38398 |
Total number of polymer chains | 10 |
Total formula weight | 131921.36 |
Authors | Williams, R.S.,Lee, M.S.,Hau, D.D.,Glover, J.N.M. (deposition date: 2004-04-22, release date: 2004-05-11, Last modification date: 2011-07-13) |
Primary citation | Williams, R.S.,Lee, M.S.,Hau, D.D.,Glover, J.N.M. Structural basis of phosphopeptide recognition by the BRCT domain of BRCA1 Nat.Struct.Mol.Biol., 11:519-525, 2004 Cited by PubMed: 15133503DOI: 10.1038/nsmb776 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.3 Å) |
Structure validation
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