Structural basis for 3' end recognition of nucleic acids by the Drosophila Argonaute 2 PAZ domain

Summary for 1T2S

Related1t2s 1UPO
Descriptor5'-D(*CP*TP*CP*AP*C)-3', Argonaute 2 (2 entities in total)
Functional Keywordsnucleic acid binding protein, dna, nucleic acid binding protein-dna complex, nucleic acid binding protein/dna
Biological sourceDrosophila melanogaster (fruit fly)
Total number of polymer chains2
Total molecular weight15368.96
Lingel, A.,Simon, B.,Izaurralde, E.,Sattler, M. (deposition date: 2004-04-22, release date: 2004-06-01, Last modification date: 2011-07-13)
Primary citation
Lingel, A.,Simon, B.,Izaurralde, E.,Sattler, M.
Nucleic acid 3'-end recognition by the Argonaute2 PAZ domain.
Nat.Struct.Mol.Biol., 11:576-577, 2004
PubMed: 15156196 (PDB entries with the same primary citation)
DOI: 10.1038/nsmb777
MImport into Mendeley
Experimental method

Structure validation

ClashscoreRamachandran outliersSidechain outliers100 5.3%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all NMR structures
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PDB entries from 2020-09-23