7W5B
| The cryo-EM structure of human C* complex | Descriptor: | 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA helicase DHX8, ... | Authors: | Zhan, X, Lu, Y, Shi, Y. | Deposit date: | 2021-11-29 | Release date: | 2022-06-22 | Last modified: | 2022-08-17 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | Mechanism of exon ligation by human spliceosome. Mol.Cell, 82, 2022
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7W5A
| The cryo-EM structure of human pre-C*-II complex | Descriptor: | 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA helicase DHX8, ... | Authors: | Zhan, X, Lu, Y, Shi, Y. | Deposit date: | 2021-11-29 | Release date: | 2022-06-22 | Last modified: | 2022-08-17 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Mechanism of exon ligation by human spliceosome. Mol.Cell, 82, 2022
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7W59
| The cryo-EM structure of human pre-C*-I complex | Descriptor: | 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA helicase DHX8, ... | Authors: | Zhan, X, Lu, Y, Shi, Y. | Deposit date: | 2021-11-29 | Release date: | 2022-06-22 | Last modified: | 2022-08-17 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Mechanism of exon ligation by human spliceosome. Mol.Cell, 82, 2022
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7W0F
| dmDicer2-LoqsPD-dsRNA Post-dicing status | Descriptor: | Dicer-2, isoform A, Loquacious, ... | Authors: | Su, S, Wang, J, Wang, H.W, Ma, J. | Deposit date: | 2021-11-18 | Release date: | 2022-04-27 | Last modified: | 2022-07-27 | Method: | ELECTRON MICROSCOPY (4.55 Å) | Cite: | Structural insights into dsRNA processing by Drosophila Dicer-2-Loqs-PD. Nature, 607, 2022
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7W0E
| dmDicer2-LoqsPD-dsRNA Active-dicing status | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Dicer-2, isoform A, ... | Authors: | Su, S, Wang, J, Wang, H.W, Ma, J. | Deposit date: | 2021-11-18 | Release date: | 2022-04-27 | Last modified: | 2022-07-27 | Method: | ELECTRON MICROSCOPY (4.03 Å) | Cite: | Structural insights into dsRNA processing by Drosophila Dicer-2-Loqs-PD. Nature, 607, 2022
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7W0D
| Dicer2-LoqsPD-dsRNA complex at mid-translocation state | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Dicer-2, isoform A, ... | Authors: | Su, S, Wang, J, Wang, H.W, Ma, J. | Deposit date: | 2021-11-18 | Release date: | 2022-04-27 | Last modified: | 2022-07-27 | Method: | ELECTRON MICROSCOPY (4.18 Å) | Cite: | Structural insights into dsRNA processing by Drosophila Dicer-2-Loqs-PD. Nature, 607, 2022
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7W0C
| Dicer2-Loqs-PD-dsRNA complex at early-translocation state | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Dicer-2, isoform A, ... | Authors: | Su, S, Wang, J, Wang, H.W, Ma, J. | Deposit date: | 2021-11-18 | Release date: | 2022-04-27 | Last modified: | 2022-07-27 | Method: | ELECTRON MICROSCOPY (3.93 Å) | Cite: | Structural insights into dsRNA processing by Drosophila Dicer-2-Loqs-PD. Nature, 607, 2022
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7W0B
| Dicer2-LoqsPD complex at apo status | Descriptor: | Dicer-2, isoform A, Loquacious, ... | Authors: | Su, S, Wang, J, Wang, H.W, Ma, J. | Deposit date: | 2021-11-18 | Release date: | 2022-04-27 | Last modified: | 2022-07-27 | Method: | ELECTRON MICROSCOPY (3.33 Å) | Cite: | Structural insights into dsRNA processing by Drosophila Dicer-2-Loqs-PD. Nature, 607, 2022
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7W0A
| dmDicer2-LoqsPD-dsRNA Dimer status | Descriptor: | Dicer-2, isoform A, Loquacious, ... | Authors: | Su, S, Wang, J, Wang, H.W, Ma, J. | Deposit date: | 2021-11-18 | Release date: | 2022-04-27 | Last modified: | 2022-07-27 | Method: | ELECTRON MICROSCOPY (3.12 Å) | Cite: | Structural insights into dsRNA processing by Drosophila Dicer-2-Loqs-PD. Nature, 607, 2022
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7VPX
| The cryo-EM structure of the human pre-A complex | Descriptor: | 5SS, DnaJ homolog subfamily C member 8, PHD finger-like domain-containing protein 5A, ... | Authors: | Zhang, X, Zhan, X, Shi, Y. | Deposit date: | 2021-10-18 | Release date: | 2023-05-03 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structural insights into branch site proofreading by human spliceosome. Nat.Struct.Mol.Biol., 2024
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7VG3
| Cryo-EM structure of Arabidopsis DCL3 in complex with a 30-bp RNA | Descriptor: | CALCIUM ION, Dicer-like 3, TAS1a RNA forward strand (5'-phosphorylated), ... | Authors: | Wang, Q, Du, J. | Deposit date: | 2021-09-14 | Release date: | 2021-10-27 | Last modified: | 2021-12-15 | Method: | ELECTRON MICROSCOPY (3.73 Å) | Cite: | Mechanism of siRNA production by a plant Dicer-RNA complex in dicing-competent conformation. Science, 374, 2021
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7VG2
| Cryo-EM structure of Arabidopsis DCL3 in complex with a 40-bp RNA | Descriptor: | CALCIUM ION, Dicer-like 3, TAS1a forward strand (5'-phosphorylation), ... | Authors: | Wang, Q, Du, J. | Deposit date: | 2021-09-14 | Release date: | 2021-10-27 | Last modified: | 2021-12-15 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Mechanism of siRNA production by a plant Dicer-RNA complex in dicing-competent conformation. Science, 374, 2021
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7V6C
| Structure of the Dicer-2-R2D2 heterodimer bound to small RNA duplex | Descriptor: | Dicer-2, isoform A, R2D2, ... | Authors: | Yamaguchi, S, Nishizawa, T, Kusakizako, T, Yamashita, K, Tomita, A, Hirano, H, Nishimasu, H, Nureki, O. | Deposit date: | 2021-08-20 | Release date: | 2022-03-23 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structure of the Dicer-2-R2D2 heterodimer bound to a small RNA duplex. Nature, 607, 2022
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7V6B
| Structure of the Dicer-2-R2D2 heterodimer | Descriptor: | Dicer-2, isoform A, R2D2 | Authors: | Yamaguchi, S, Nishizawa, T, Kusakizako, T, Yamashita, K, Tomita, A, Hirano, H, Nishimasu, H, Nureki, O. | Deposit date: | 2021-08-20 | Release date: | 2022-03-23 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structure of the Dicer-2-R2D2 heterodimer bound to a small RNA duplex. Nature, 607, 2022
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7V2Y
| cryo-EM structure of yeast THO complex with Sub2 | Descriptor: | ATP-dependent RNA helicase SUB2, Protein TEX1, THO complex subunit 2, ... | Authors: | Chen, C, Tan, M, Wu, Z, Wu, J, Lei, M. | Deposit date: | 2021-08-10 | Release date: | 2022-07-27 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structural and functional insights into R-loop prevention and mRNA export by budding yeast THO-Sub2 complex. Sci Bull (Beijing), 66, 2021
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7UJB
| N-terminal domain deletion variant of Eta | Descriptor: | DEAD/DEAH box RNA helicase | Authors: | Qayyum, M.Z, Murakami, K.S. | Deposit date: | 2022-03-30 | Release date: | 2022-08-10 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (4.12 Å) | Cite: | The structure and activities of the archaeal transcription termination factor Eta detail vulnerabilities of the transcription elongation complex. Proc.Natl.Acad.Sci.USA, 119, 2022
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7TRA
| Cascade complex from type I-A CRISPR-Cas system | Descriptor: | CRISPR-associated endonuclease Cas3-HD, CRISPR-associated helicase Cas3, Cas11a, ... | Authors: | Hu, C, Ni, D, Nam, K.H, Majumdar, S, McLean, J, Stahlberg, H, Terns, M, Ke, A. | Deposit date: | 2022-01-28 | Release date: | 2022-08-10 | Last modified: | 2022-08-17 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Allosteric control of type I-A CRISPR-Cas3 complexes and establishment as effective nucleic acid detection and human genome editing tools. Mol.Cell, 82, 2022
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7TR8
| Cascade complex from type I-A CRISPR-Cas system | Descriptor: | CRISPR-associated endonuclease Cas3-HD, CRISPR-associated helicase Cas3, Cas11a, ... | Authors: | Hu, C, Ni, D, Nam, K.H, Majumdar, S, McLean, J, Stahlberg, H, Terns, M, Ke, A. | Deposit date: | 2022-01-28 | Release date: | 2022-08-10 | Last modified: | 2022-08-17 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Allosteric control of type I-A CRISPR-Cas3 complexes and establishment as effective nucleic acid detection and human genome editing tools. Mol.Cell, 82, 2022
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7TO2
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7TO1
| Cryo-EM structure of RIG-I bound to the end of p3SLR30 (+ATP) | Descriptor: | Antiviral innate immune response receptor RIG-I, ZINC ION, p3SLR30 | Authors: | Wang, W, Pyle, A.M. | Deposit date: | 2022-01-22 | Release date: | 2022-11-02 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.66 Å) | Cite: | The RIG-I receptor adopts two different conformations for distinguishing host from viral RNA ligands. Mol.Cell, 82, 2022
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7TO0
| Cryo-EM structure of RIG-I in complex with OHdsRNA | Descriptor: | Antiviral innate immune response receptor RIG-I, OHdsRNA, ZINC ION | Authors: | Wang, W, Pyle, A.M. | Deposit date: | 2022-01-22 | Release date: | 2022-11-02 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | The RIG-I receptor adopts two different conformations for distinguishing host from viral RNA ligands. Mol.Cell, 82, 2022
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7TNZ
| Cryo-EM structure of RIG-I in complex with p1dsRNA | Descriptor: | Antiviral innate immune response receptor RIG-I, ZINC ION, p1dsRNA | Authors: | Wang, W, Pyle, A.M. | Deposit date: | 2022-01-22 | Release date: | 2022-11-02 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.54 Å) | Cite: | The RIG-I receptor adopts two different conformations for distinguishing host from viral RNA ligands. Mol.Cell, 82, 2022
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7TNY
| Cryo-EM structure of RIG-I in complex with p2dsRNA | Descriptor: | Antiviral innate immune response receptor RIG-I, ZINC ION, p2dsRNA | Authors: | Wang, W, Pyle, A.M. | Deposit date: | 2022-01-22 | Release date: | 2022-11-02 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | The RIG-I receptor adopts two different conformations for distinguishing host from viral RNA ligands. Mol.Cell, 82, 2022
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7TNX
| Cryo-EM structure of RIG-I in complex with p3dsRNA | Descriptor: | Antiviral innate immune response receptor RIG-I, ZINC ION, p3dsRNAa, ... | Authors: | Wang, W, Pyle, A.M. | Deposit date: | 2022-01-22 | Release date: | 2022-11-02 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.54 Å) | Cite: | The RIG-I receptor adopts two different conformations for distinguishing host from viral RNA ligands. Mol.Cell, 82, 2022
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7SSG
| Mfd DNA complex | Descriptor: | DNA (5'-D(P*TP*GP*GP*CP*GP*GP*CP*GP*AP*GP*GP*C)-3'), DNA (5'-D(P*TP*TP*GP*CP*CP*TP*CP*GP*CP*TP*GP*CP*CP*A)-3'), Transcription-repair-coupling factor | Authors: | Oakley, A.J, Xu, Z.-Q. | Deposit date: | 2021-11-11 | Release date: | 2022-05-25 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (5.2 Å) | Cite: | Mechanism of transcription modulation by the transcription-repair coupling factor. Nucleic Acids Res., 50, 2022
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