7TNX

Cryo-EM structure of RIG-I in complex with p3dsRNA

Summary for 7TNX

• Entry DOI: 10.2210/pdb7tnx/pdb
• EMDB information: 26022
• Descriptor: Antiviral innate immune response receptor RIG-I, p3dsRNAa, p3dsRNAb, ... (4 entities in total)
• Functional Keywords: ribonucleoprotein complex, rna sensor, rig-i like receptor, immune system, immune system-rna complex, immune system/rna
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 3
• Total formula weight: 122908.44

Authors

Wang, W.,Pyle, A.M. (deposition date: 2022-01-22, release date: 2022-11-02, Last modification date: 2024-06-05)

• Primary citation: Wang, W.,Pyle, A.M.; The RIG-I receptor adopts two different conformations for distinguishing host from viral RNA ligands.; Mol.Cell, 82:4131-4144.e6, 2022; PubMed: 36272408; DOI: 10.1016/j.molcel.2022.09.029

Experimental method

ELECTRON MICROSCOPY (3.54 Å)