Summary for 7TR8
Entry DOI | 10.2210/pdb7tr8/pdb |
EMDB information | 26082 |
Descriptor | CRISPR-associated helicase Cas3, Cas8, Cas11a, ... (8 entities in total) |
Functional Keywords | crispr, cascade, cas3, type i-a, genome editing, rna binding protein |
Biological source | Pyrococcus furiosus DSM 3638 More |
Total number of polymer chains | 17 |
Total formula weight | 489877.73 |
Authors | Hu, C.,Ni, D.,Nam, K.H.,Majumdar, S.,McLean, J.,Stahlberg, H.,Terns, M.,Ke, A. (deposition date: 2022-01-28, release date: 2022-08-10, Last modification date: 2022-08-17) |
Primary citation | Hu, C.,Ni, D.,Nam, K.H.,Majumdar, S.,McLean, J.,Stahlberg, H.,Terns, M.P.,Ke, A. Allosteric control of type I-A CRISPR-Cas3 complexes and establishment as effective nucleic acid detection and human genome editing tools. Mol.Cell, 82:2754-2768.e5, 2022 Cited by PubMed: 35835111DOI: 10.1016/j.molcel.2022.06.007 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.6 Å) |
Structure validation
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