6NRC
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![BU of 6nrc by Molmil](/molmil-images/mine/6nrc) | hTRiC-hPFD Class3 | Descriptor: | Prefoldin subunit 1, Prefoldin subunit 2, Prefoldin subunit 3, ... | Authors: | Gestaut, D, Roh, S.H, Ma, B, Pintilie, G, Joachimiak, L.A, Leitner, A, Walzthoeni, T, Aebersold, R, Chiu, W, Frydman, J. | Deposit date: | 2019-01-23 | Release date: | 2019-06-19 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (8.3 Å) | Cite: | The Chaperonin TRiC/CCT Associates with Prefoldin through a Conserved Electrostatic Interface Essential for Cellular Proteostasis. Cell, 177, 2019
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1NAS
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![BU of 1nas by Molmil](/molmil-images/mine/1nas) | SEPIAPTERIN REDUCTASE COMPLEXED WITH N-ACETYL SEROTONIN | Descriptor: | N-ACETYL SEROTONIN, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, OXALOACETATE ION, ... | Authors: | Auerbach, G, Herrmann, A, Bacher, A, Huber, R. | Deposit date: | 1998-03-26 | Release date: | 1999-03-30 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The 1.25 A crystal structure of sepiapterin reductase reveals its binding mode to pterins and brain neurotransmitters. EMBO J., 16, 1997
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6CHA
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![BU of 6cha by Molmil](/molmil-images/mine/6cha) | |
6NRD
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![BU of 6nrd by Molmil](/molmil-images/mine/6nrd) | hTRiC-hPFD Class4 | Descriptor: | Prefoldin subunit 1, Prefoldin subunit 2, Prefoldin subunit 3, ... | Authors: | Gestaut, D.R, Roh, S.H, Ma, B, Pintilie, G, Joachimiak, L.A, Leitner, A, Walzthoeni, T, Aebersold, R, Chiu, W, Frydman, J. | Deposit date: | 2019-01-23 | Release date: | 2019-06-19 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (8.2 Å) | Cite: | The Chaperonin TRiC/CCT Associates with Prefoldin through a Conserved Electrostatic Interface Essential for Cellular Proteostasis. Cell, 177, 2019
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3TYK
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![BU of 3tyk by Molmil](/molmil-images/mine/3tyk) | Crystal structure of aminoglycoside phosphotransferase APH(4)-Ia | Descriptor: | CHLORIDE ION, HYGROMYCIN B VARIANT, Hygromycin-B 4-O-kinase | Authors: | Stogios, P.J, Shabalin, I.G, Shakya, T, Evdokmova, E, Fan, Y, Chruszcz, M, Minor, W, Wright, G.D, Savchenko, A, Anderson, W.F, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2011-09-26 | Release date: | 2011-10-12 | Last modified: | 2022-04-13 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structure and function of APH(4)-Ia, a hygromycin B resistance enzyme. J.Biol.Chem., 286, 2011
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3H30
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![BU of 3h30 by Molmil](/molmil-images/mine/3h30) | Crystal structure of the catalytic subunit of human protein kinase CK2 with 5,6-dichloro-1-beta-D-ribofuranosylbenzimidazole | Descriptor: | 5,6-dichloro-1-beta-D-ribofuranosyl-1H-benzimidazole, CHLORIDE ION, Casein kinase II subunit alpha | Authors: | Niefind, K, Raaf, J, Issinger, O.-G. | Deposit date: | 2009-04-15 | Release date: | 2009-05-12 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.56 Å) | Cite: | The CK2alpha/CK2beta Interface of Human Protein Kinase CK2 Harbors a Binding Pocket for Small Molecules Chem.Biol., 15, 2008
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6O1D
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![BU of 6o1d by Molmil](/molmil-images/mine/6o1d) | |
4TMK
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![BU of 4tmk by Molmil](/molmil-images/mine/4tmk) | |
1XDJ
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![BU of 1xdj by Molmil](/molmil-images/mine/1xdj) | |
4OD5
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![BU of 4od5 by Molmil](/molmil-images/mine/4od5) | |
2QR0
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![BU of 2qr0 by Molmil](/molmil-images/mine/2qr0) | Structure of VEGF complexed to a Fab containing TYR and SER in the CDRs | Descriptor: | Fab-Fragment Heavy Chain, Fab-Fragment Light Chain, Vascular endothelial growth factor A | Authors: | Wiesmann, C. | Deposit date: | 2007-07-27 | Release date: | 2007-08-14 | Last modified: | 2017-10-25 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | High-throughput generation of synthetic antibodies from highly functional minimalist phage-displayed libraries J.Mol.Biol., 373, 2007
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2DSR
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![BU of 2dsr by Molmil](/molmil-images/mine/2dsr) | Structural Basis for the Inhibition of Insulin-like Growth Factors by IGF Binding Proteins | Descriptor: | Insulin-like growth factor IB, Insulin-like growth factor-binding protein 4 | Authors: | Sitar, T, Popowicz, G.M, Siwanowicz, I, Huber, R, Holak, T.A. | Deposit date: | 2006-07-05 | Release date: | 2006-08-22 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural basis for the inhibition of insulin-like growth factors by insulin-like growth factor-binding proteins. Proc.Natl.Acad.Sci.Usa, 103, 2006
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3CSH
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![BU of 3csh by Molmil](/molmil-images/mine/3csh) | |
1IQZ
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![BU of 1iqz by Molmil](/molmil-images/mine/1iqz) | OXIDIZED [4Fe-4S] FERREDOXIN FROM BACILLUS THERMOPROTEOLYTICUS (FORM I) | Descriptor: | Ferredoxin, IRON/SULFUR CLUSTER, SULFATE ION | Authors: | Fukuyama, K, Okada, T, Kakuta, Y, Takahashi, Y. | Deposit date: | 2001-08-30 | Release date: | 2002-02-13 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (0.92 Å) | Cite: | Atomic resolution structures of oxidized [4Fe-4S] ferredoxin from Bacillus thermoproteolyticus in two crystal forms: systematic distortion of [4Fe-4S] cluster in the protein. J.Mol.Biol., 315, 2002
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1Q7S
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![BU of 1q7s by Molmil](/molmil-images/mine/1q7s) | Crystal structure of bit1 | Descriptor: | bit1 | Authors: | De Pereda, J.M, Waas, W.F, Jan, Y, Ruoslahti, E, Schimmel, P, Pascual, J. | Deposit date: | 2003-08-19 | Release date: | 2003-12-16 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of a human peptidyl-tRNA hydrolase reveals a new fold and suggests basis for a bifunctional activity. J.Biol.Chem., 279, 2004
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3D1A
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3PCA
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![BU of 3pca by Molmil](/molmil-images/mine/3pca) | STRUCTURE OF PROTOCATECHUATE 3,4-DIOXYGENASE COMPLEXED WITH 3,4-DIHYDROXYBENZOATE | Descriptor: | 3,4-DIHYDROXYBENZOIC ACID, BETA-MERCAPTOETHANOL, FE (III) ION, ... | Authors: | Orville, A.M, Lipscomb, J.D, Ohlendorf, D.H. | Deposit date: | 1997-07-18 | Release date: | 1998-01-21 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structures of substrate and substrate analog complexes of protocatechuate 3,4-dioxygenase: endogenous Fe3+ ligand displacement in response to substrate binding. Biochemistry, 36, 1997
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1ON8
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![BU of 1on8 by Molmil](/molmil-images/mine/1on8) | Crystal structure of mouse alpha-1,4-N-acetylhexosaminyltransferase (EXTL2) with UDP and GlcUAb(1-3)Galb(1-O)-naphthalenelmethanol an acceptor substrate analog | Descriptor: | 1,2-ETHANEDIOL, Alpha-1,4-N-acetylhexosaminyltransferase EXTL2, MANGANESE (II) ION, ... | Authors: | Pedersen, L.C, Dong, J, Taniguchi, F, Kitagawa, H, Krahn, J.M, Pedersen, L.G, Sugahara, K, Negishi, M. | Deposit date: | 2003-02-27 | Release date: | 2003-04-22 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structure of an alpha-1,4-N-acetylhexosaminyltransferase (EXTL2), a member of the exostosin gene family involved in heparan sulfate biosynthesis J.Biol.Chem., 278, 2003
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1MDM
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![BU of 1mdm by Molmil](/molmil-images/mine/1mdm) | INHIBITED FRAGMENT OF ETS-1 AND PAIRED DOMAIN OF PAX5 BOUND TO DNA | Descriptor: | C-ETS-1 PROTEIN, PAIRED BOX PROTEIN PAX-5, PAX5/ETS BINDING SITE ON THE MB-1 PROMOTER | Authors: | Garvie, C.W, Pufall, M.A, Graves, B.J, Wolberger, C. | Deposit date: | 2002-08-07 | Release date: | 2002-12-11 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | STRUCTURAL ANALYSIS OF THE AUTOINHIBITION OF ETS-1 AND ITS ROLE IN PROTEIN PARTNERSHIPS J.Biol.Chem., 277, 2002
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4B7T
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![BU of 4b7t by Molmil](/molmil-images/mine/4b7t) | Glycogen Synthase Kinase 3 Beta complexed with Axin Peptide and Leucettine L4 | Descriptor: | (5Z)-5-(1,3-benzodioxol-5-ylmethylidene)-3-methyl-2-(propan-2-ylamino)imidazol-4-one, AXIN-1, GLYCOGEN SYNTHASE KINASE-3 BETA | Authors: | Oberholzer, A.E, Pearl, L.H. | Deposit date: | 2012-08-22 | Release date: | 2013-01-30 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.772 Å) | Cite: | Selectivity, Cocrystal Structures, and Neuroprotective Properties of Leucettines, a Family of Protein Kinase Inhibitors Derived from the Marine Sponge Alkaloid Leucettamine B. J.Med.Chem., 55, 2012
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7B9X
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![BU of 7b9x by Molmil](/molmil-images/mine/7b9x) | NMR2 structure of TRIM24-BD in complex with a precursor of IACS-9571 | Descriptor: | N-{6-[3-(4-Aminobutoxy)-5-propoxyphenoxy]-1,3-dimethyl-2-oxo-2,3-dihydro-1H-1,3-benzodiazol-5-yl}-3,4-dimethoxybenzene-1-sulfonamide, Transcription intermediary factor 1-alpha | Authors: | Orts, J, Torres, F, Milbradt, A.G, Walser, R. | Deposit date: | 2020-12-14 | Release date: | 2022-01-12 | Last modified: | 2024-06-19 | Method: | SOLUTION NMR | Cite: | NMR Molecular Replacement Provides New Insights into Binding Modes to Bromodomains of BRD4 and TRIM24. J.Med.Chem., 65, 2022
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5DYX
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6XL1
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![BU of 6xl1 by Molmil](/molmil-images/mine/6xl1) | crystal structure of cA4-activated Card1(D294N) | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Card1, MANGANESE (II) ION, ... | Authors: | Rostol, J, Xie, W, Patel, D.J, Marraffini, L. | Deposit date: | 2020-06-27 | Release date: | 2020-12-30 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | The Card1 nuclease provides defence during type III CRISPR immunity. Nature, 590, 2021
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5E3C
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![BU of 5e3c by Molmil](/molmil-images/mine/5e3c) | Structure of human DPP3 in complex with hemorphin like opioid peptide IVYPW | Descriptor: | Dipeptidyl peptidase 3, IVYPW, MAGNESIUM ION, ... | Authors: | Kumar, P, Reithofer, V, Reisinger, M, Pavkov-Keller, T, Wallner, S, Macheroux, P, Gruber, K. | Deposit date: | 2015-10-02 | Release date: | 2016-04-13 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.765 Å) | Cite: | Substrate complexes of human dipeptidyl peptidase III reveal the mechanism of enzyme inhibition. Sci Rep, 6, 2016
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6XB5
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![BU of 6xb5 by Molmil](/molmil-images/mine/6xb5) | |