6XB5

Structure of Trichoplusia ni poxin in post-reactive state with Gp[2'-5']Ap[3']

Summary for 6XB5

Entry DOI	10.2210/pdb6xb5/pdb
Descriptor	Poxin, 2',5'-GpAp (2 entities in total)
Functional Keywords	poxin, nuclease, hdd13, lepidoptera, moth, butterfly, innate immunity, cgas, cgamp, sting, hydrolase
Biological source	Trichoplusia ni
Total number of polymer chains	2
Total formula weight	55203.15
Authors	Eaglesham, J.B.,McCarty, K.L.,Kranzusch, P.J. (deposition date: 2020-06-05, release date: 2020-11-25, Last modification date: 2023-10-18)
Primary citation	Eaglesham, J.B.,McCarty, K.L.,Kranzusch, P.J. Structures of diverse poxin cGAMP nucleases reveal a widespread role for cGAS-STING evasion in host-pathogen conflict. Elife, 9:-, 2020 Cited by PubMed: 33191912 DOI: 10.7554/eLife.59753 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.9 Å)

Structure validation