Summary for 3TYK
| Entry DOI | 10.2210/pdb3tyk/pdb |
| Descriptor | Hygromycin-B 4-O-kinase, HYGROMYCIN B VARIANT, CHLORIDE ION, ... (4 entities in total) |
| Functional Keywords | midwest center for structural genomics, mcsg, psi-2, aminoglycoside phosphotransferase, eukaryotic protein kinase-like fold, phosphotransferase/kinase, antibiotic resistance, aminoglycoside binding, phosphorylation, transferase-antibiotic complex, cytoplasmic, protein structure initiative, transferase/antibiotic |
| Biological source | Escherichia coli |
| Total number of polymer chains | 1 |
| Total formula weight | 41503.21 |
| Authors | Stogios, P.J.,Shabalin, I.G.,Shakya, T.,Evdokmova, E.,Fan, Y.,Chruszcz, M.,Minor, W.,Wright, G.D.,Savchenko, A.,Anderson, W.F.,Midwest Center for Structural Genomics (MCSG) (deposition date: 2011-09-26, release date: 2011-10-12, Last modification date: 2022-04-13) |
| Primary citation | Stogios, P.J.,Shakya, T.,Evdokimova, E.,Savchenko, A.,Wright, G.D. Structure and function of APH(4)-Ia, a hygromycin B resistance enzyme. J.Biol.Chem., 286:1966-1975, 2011 Cited by PubMed: 21084294PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
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