PDB: 36667 resultsInfo pagesStatus searchChemie searchBIRD

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7Q78	Room temperature structure of RNase A at 72 MPa helium gas pressure in a sapphire capillary Descriptor: CHLORIDE ION, Ribonuclease pancreatic, SODIUM ION, ... Authors: Lieske, J, Guenther, S, Saouane, S, Meents, A. Deposit date: 2021-11-09 Release date: 2022-11-16 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.52 Å) Cite: Fixed-target high-pressure macromolecular crystallography To Be Published
7Q7B	Room temperature structure of RNase A at atmospheric pressure in a sapphire capillary after high helium gas pressure release Descriptor: CHLORIDE ION, Ribonuclease pancreatic, SODIUM ION, ... Authors: Lieske, J, Guenther, S, Saouane, S, Meents, A. Deposit date: 2021-11-09 Release date: 2022-11-16 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.78 Å) Cite: Fixed-target high-pressure macromolecular crystallography To Be Published
7Q7D	Room temperature structure of the human Serine/Threonine Kinase 17B (STK17B/DRAK2) in complex with ATP/ADP at 111 MPa helium gas pressure in a sapphire capillary Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Serine/threonine-protein kinase 17B Authors: Lieske, J, Guenther, S, Saouane, S, Meents, A. Deposit date: 2021-11-09 Release date: 2022-11-16 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Fixed-target high-pressure macromolecular crystallography To Be Published
7Q7E	Room temperature structure of the human Serine/Threonine Kinase 17B (STK17B/DRAK2) in complex with ATP/ADP at atmospheric pressure in a sapphire capillary after high helium gas pressure release Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Serine/threonine-protein kinase 17B Authors: Lieske, J, Guenther, S, Saouane, S, Meents, A. Deposit date: 2021-11-09 Release date: 2022-11-16 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.85 Å) Cite: Fixed-target high-pressure macromolecular crystallography To Be Published
7SR9	Human alpha-thrombin with 180- and 220- loops replaced with homologous loops from protein C Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, SULFATE ION, ... Authors: Di Cera, E, Ruben, E.A, Chen, Z. Deposit date: 2021-11-08 Release date: 2021-12-08 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.1 Å) Cite: The active site region plays a critical role in Na + binding to thrombin. J.Biol.Chem., 298, 2022
7SR8	Molecular mechanism of the the wake-promoting agent TAK-925 Descriptor: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Hypocretin receptor type 2, ... Authors: Yin, J, Chapman, K, Lian, P, De Brabander, J.K, Rosenbaum, D.M. Deposit date: 2021-11-08 Release date: 2022-06-08 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Molecular mechanism of the wake-promoting agent TAK-925. Nat Commun, 13, 2022
7SRS	5-HT2B receptor bound to LSD in complex with beta-arrestin1 obtained by cryo-electron microscopy (cryoEM) Descriptor: (8alpha)-N,N-diethyl-6-methyl-9,10-didehydroergoline-8-carboxamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, 5-hydroxytryptamine receptor 2B, ... Authors: Barros-Alvarez, X, Cao, C, Panova, O, Roth, B.L, Skiniotis, G. Deposit date: 2021-11-08 Release date: 2022-09-21 Last modified: 2022-10-19 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Signaling snapshots of a serotonin receptor activated by the prototypical psychedelic LSD. Neuron, 110, 2022
7SRQ	5-HT2B receptor bound to LSD obtained by cryo-electron microscopy (cryoEM) Descriptor: (8alpha)-N,N-diethyl-6-methyl-9,10-didehydroergoline-8-carboxamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, 5-hydroxytryptamine receptor 2B Authors: Barros-Alvarez, X, Cao, C, Panova, O, Roth, B.L, Skiniotis, G. Deposit date: 2021-11-08 Release date: 2022-09-21 Last modified: 2022-10-19 Method: ELECTRON MICROSCOPY (2.7 Å) Cite: Signaling snapshots of a serotonin receptor activated by the prototypical psychedelic LSD. Neuron, 110, 2022
7SRR	5-HT2B receptor bound to LSD in complex with heterotrimeric mini-Gq protein obtained by cryo-electron microscopy (cryoEM) Descriptor: (8alpha)-N,N-diethyl-6-methyl-9,10-didehydroergoline-8-carboxamide, 5-hydroxytryptamine receptor 2B, G protein subunit q (Gi2-mini-Gq chimera), ... Authors: Barros-Alvarez, X, Kim, K, Panova, O, Cao, C, Roth, B.L, Skiniotis, G. Deposit date: 2021-11-08 Release date: 2022-09-21 Last modified: 2022-10-19 Method: ELECTRON MICROSCOPY (2.9 Å) Cite: Signaling snapshots of a serotonin receptor activated by the prototypical psychedelic LSD. Neuron, 110, 2022
7SR6	Human Endogenous Retrovirus (HERV-K) reverse transcriptase ternary complex with dsDNA template Primer and dNTP Descriptor: 1,2-ETHANEDIOL, 1,4-DIETHYLENE DIOXIDE, 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, ... Authors: Baldwin, E.T, Nichols, C. Deposit date: 2021-11-08 Release date: 2022-07-20 Method: X-RAY DIFFRACTION (2.62 Å) Cite: Human endogenous retrovirus-K (HERV-K) reverse transcriptase (RT) structure and biochemistry reveals remarkable similarities to HIV-1 RT and opportunities for HERV-K-specific inhibition. Proc.Natl.Acad.Sci.USA, 119, 2022
7VVG	Crystal Structure of HRasG12V(GMPPNP-bound) in complex with the Ras-binding domain(RBD) of SIN1 Descriptor: GTPase HRas, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... Authors: Zheng, Y.Y, Zhou, C. Deposit date: 2021-11-06 Release date: 2022-05-18 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Structural insights into Ras regulation by SIN1. Proc.Natl.Acad.Sci.USA, 119, 2022
7VVN	PTH-bound human PTH1R in complex with Gs (class4) Descriptor: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... Authors: Kobayashi, K, Kusakizako, T, Miyauchi, H, Tomita, A, Kobayashi, K, Shihoya, W, Yamashita, K, Nishizawa, T, Kato, H.E, Nureki, O. Deposit date: 2021-11-06 Release date: 2022-08-03 Last modified: 2023-02-15 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: Endogenous ligand recognition and structural transition of a human PTH receptor. Mol.Cell, 82, 2022
7VVK	PTH-bound human PTH1R in complex with Gs (class1) Descriptor: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... Authors: Kobayashi, K, Kusakizako, T, Miyauchi, H, Tomita, A, Kobayashi, K, Shihoya, W, Yamashita, K, Nishizawa, T, Kato, H.E, Nureki, O. Deposit date: 2021-11-06 Release date: 2022-08-03 Last modified: 2023-02-15 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Endogenous ligand recognition and structural transition of a human PTH receptor. Mol.Cell, 82, 2022
7VVM	PTH-bound human PTH1R in complex with Gs (class3) Descriptor: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... Authors: Kobayashi, K, Kusakizako, T, Miyauchi, H, Tomita, A, Kobayashi, K, Shihoya, W, Yamashita, K, Nishizawa, T, Kato, H.E, Nureki, O. Deposit date: 2021-11-06 Release date: 2022-08-03 Last modified: 2023-02-15 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Endogenous ligand recognition and structural transition of a human PTH receptor. Mol.Cell, 82, 2022
7VVJ	PTHrP-bound human PTH1R in complex with Gs Descriptor: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... Authors: Kobayashi, K, Kusakizako, T, Miyauchi, H, Tomita, A, Kobayashi, K, Shihoya, W, Yamashita, K, Nishizawa, T, Kato, H.E, Nureki, O. Deposit date: 2021-11-06 Release date: 2022-08-03 Last modified: 2023-02-15 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Endogenous ligand recognition and structural transition of a human PTH receptor. Mol.Cell, 82, 2022
7VVO	PTH-bound human PTH1R in complex with Gs (class5) Descriptor: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... Authors: Kobayashi, K, Kusakizako, T, Miyauchi, H, Tomita, A, Kobayashi, K, Shihoya, W, Yamashita, K, Nishizawa, T, Kato, H.E, Nureki, O. Deposit date: 2021-11-06 Release date: 2022-08-03 Last modified: 2023-02-15 Method: ELECTRON MICROSCOPY (4.1 Å) Cite: Endogenous ligand recognition and structural transition of a human PTH receptor. Mol.Cell, 82, 2022
7VVL	PTH-bound human PTH1R in complex with Gs (class2) Descriptor: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... Authors: Kobayashi, K, Kusakizako, T, Miyauchi, H, Tomita, A, Kobayashi, K, Shihoya, W, Yamashita, K, Nishizawa, T, Kato, H.E, Nureki, O. Deposit date: 2021-11-06 Release date: 2022-08-03 Last modified: 2023-02-15 Method: ELECTRON MICROSCOPY (2.8 Å) Cite: Endogenous ligand recognition and structural transition of a human PTH receptor. Mol.Cell, 82, 2022
7VV9	Crystal Structure of HRas(GMPPNP-bound) in complex with the Ras-binding domain(RBD) of SIN1 Descriptor: GTPase HRas, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... Authors: Zheng, Y.Y, Zhou, C. Deposit date: 2021-11-05 Release date: 2022-05-18 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Structural insights into Ras regulation by SIN1. Proc.Natl.Acad.Sci.USA, 119, 2022
7VVB	Crystal Structure of KRas4A(GMPPNP-bound) in complex with the Ras-binding domain(RBD) of SIN1 Descriptor: GTPase KRas, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... Authors: Zheng, Y.Y, Zhou, C. Deposit date: 2021-11-05 Release date: 2022-05-18 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Structural insights into Ras regulation by SIN1. Proc.Natl.Acad.Sci.USA, 119, 2022
7Q63	The tandem SH2 domains of SYK Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... Authors: Bradshaw, W.J, Katis, V.L, Chen, Z, Bountra, C, von Delft, F, Gileadi, O, Brennan, P.E. Deposit date: 2021-11-05 Release date: 2021-11-24 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.9 Å) Cite: The tandem SH2 domains of SYK To Be Published
7SQC	Ciliary C1 central pair apparatus isolated from Chlamydomonas reinhardtii Descriptor: ADENOSINE-5'-DIPHOSPHATE, CPC1, Calmodulin, ... Authors: Gui, M, Wang, X, Dutcher, S.K, Brown, A, Zhang, R. Deposit date: 2021-11-05 Release date: 2022-04-13 Last modified: 2024-06-05 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: Ciliary central apparatus structure reveals mechanisms of microtubule patterning. Nat.Struct.Mol.Biol., 29, 2022
7SQO	Structure of the orexin-2 receptor(OX2R) bound to TAK-925, Gi and scFv16 Descriptor: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... Authors: McGrath, A.P, Kang, Y, Flinspach, M. Deposit date: 2021-11-05 Release date: 2022-05-25 Last modified: 2022-07-06 Method: ELECTRON MICROSCOPY (3.17 Å) Cite: Molecular mechanism of the wake-promoting agent TAK-925. Nat Commun, 13, 2022
7Q5Y	Structure of NADH:ubichinon oxidoreductase (complex I) of the hyperthermophilic eubacterium Aquifex aeolicus Descriptor: FE2/S2 (INORGANIC) CLUSTER, FLAVIN MONONUCLEOTIDE, IRON/SULFUR CLUSTER, ... Authors: Warkentin, E, Ermler, U, Peng, G. Deposit date: 2021-11-05 Release date: 2022-11-16 Last modified: 2024-06-19 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Structure of NADH:ubichinon oxidoreductase (complex I) of the hyperthermophilic eubacterium Aquifex aeolicus To Be Published
7VV8	Crystal Structure of HRasQ61L(GMPPNP-bound) in complex with the Ras-binding domain(RBD) of SIN1 Descriptor: GTPase HRas, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... Authors: Zheng, Y.Y, Zhou, C. Deposit date: 2021-11-04 Release date: 2022-05-18 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Structural insights into Ras regulation by SIN1. Proc.Natl.Acad.Sci.USA, 119, 2022
7Q5T	The tandem SH2 domains of SYK with a bound FCER1G diphospho-ITAM peptide Descriptor: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, High affinity immunoglobulin epsilon receptor subunit gamma, ... Authors: Bradshaw, W.J, Katis, V.L, Chen, Z, Bountra, C, von Delft, F, Gileadi, O, Brennan, P.E. Deposit date: 2021-11-04 Release date: 2021-11-24 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.2 Å) Cite: The tandem SH2 domains of SYK To Be Published

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