7VVG

Crystal Structure of HRasG12V(GMPPNP-bound) in complex with the Ras-binding domain(RBD) of SIN1

Summary for 7VVG

• Entry DOI: 10.2210/pdb7vvg/pdb
• Related: 7VV8
• Descriptor: GTPase HRas, Target of rapamycin complex 2 subunit MAPKAP1, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... (5 entities in total)
• Functional Keywords: ras, rbd, cell cycle
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 29274.88

Authors

Zheng, Y.Y.,Zhou, C. (deposition date: 2021-11-06, release date: 2022-05-18, Last modification date: 2023-11-29)

• Primary citation: Zheng, Y.,Ding, L.,Meng, X.,Potter, M.,Kearney, A.L.,Zhang, J.,Sun, J.,James, D.E.,Yang, G.,Zhou, C.; Structural insights into Ras regulation by SIN1.; Proc.Natl.Acad.Sci.USA, 119:e2119990119-e2119990119, 2022; PubMed: 35522713; DOI: 10.1073/pnas.2119990119

Experimental method

X-RAY DIFFRACTION (1.7 Å)