7VVG
Crystal Structure of HRasG12V(GMPPNP-bound) in complex with the Ras-binding domain(RBD) of SIN1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | GTPase HRas | polymer | 166 | 18917.3 | 1 | UniProt (P01112) Pfam (PF00071) | Homo sapiens (human) | H-Ras-1,Ha-Ras,Transforming protein p21,c-H-ras,p21ras |
| 2 | B (C) | Target of rapamycin complex 2 subunit MAPKAP1 | polymer | 87 | 9811.1 | 1 | UniProt (Q9BPZ7) | Homo sapiens (human) | TORC2 subunit MAPKAP1,Mitogen-activated protein kinase 2-associated protein 1,Stress-activated map kinase-interacting protein 1,SAPK-interacting protein 1,mSIN1 |
| 3 | C (A) | PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | non-polymer | 522.2 | 1 | Chemie (GNP) | |||
| 4 | D (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 5 | E, F (A, C) | water | water | 18.0 | 305 | Chemie (HOH) |
Sequence modifications
A: 1 - 166 (UniProt: P01112)
| PDB | External Database | Details |
|---|---|---|
| Val 12 | Gly 12 | variant |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 28728.4 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 546.5 | |
| All* | Total formula weight | 29274.9 |
