4M17
 
 | | Crystal Structure of Surfactant Protein-D D325A/R343V mutant | | Descriptor: | CALCIUM ION, Pulmonary surfactant-associated protein D | | Authors: | Goh, B.C, Rynkiewicz, M.J, Cafarella, T.R, White, M.R, Hartshorn, K.L, Allen, K, Crouch, E.C, Calin, O, Seeberger, P.H, Schulten, K, Seaton, B.A. | | Deposit date: | 2013-08-02 | | Release date: | 2013-12-04 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.096 Å) | | Cite: | Molecular mechanisms of inhibition of influenza by surfactant protein d revealed by large-scale molecular dynamics simulation.
Biochemistry, 52, 2013
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1B08
 | | LUNG SURFACTANT PROTEIN D (SP-D) (FRAGMENT) | | Descriptor: | CALCIUM ION, PROTEIN (LUNG SURFACTANT PROTEIN D) | | Authors: | Hakansson, K, Lim, N.K, Hoppe, H.-J, Reid, K.B.M. | | Deposit date: | 1998-11-18 | | Release date: | 1999-12-01 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Crystal structure of the trimeric alpha-helical coiled-coil and the three lectin domains of human lung surfactant protein D.
Structure Fold.Des., 7, 1999
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1U0N
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1U0O
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1UEX
 | | Crystal structure of von Willebrand Factor A1 domain complexed with snake venom bitiscetin | | Descriptor: | bitiscetin alpha chain, bitiscetin beta chain, von Willebrand Factor | | Authors: | Maita, N, Nishio, K, Nishimoto, E, Matsui, T, Shikamoto, Y, Morita, T, Sadler, J.E, Mizuno, H. | | Deposit date: | 2003-05-22 | | Release date: | 2003-09-30 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.85 Å) | | Cite: | Crystal structure of von Willebrand factor A1 domain complexed with snake venom, bitiscetin. Insight into glycoprotein Ibalpha binding mechanism induced by snake venom proteins.
J.Biol.Chem., 278, 2003
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1V7P
 | | Structure of EMS16-alpha2-I domain complex | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, EMS16 A chain, ... | | Authors: | Horii, K, Okuda, D, Morita, T, Mizuno, H. | | Deposit date: | 2003-12-19 | | Release date: | 2004-09-07 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Crystal structure of EMS16 in complex with the integrin alpha2-I domain
J.Mol.Biol., 341, 2004
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1HYR
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1J35
 | | Crystal Structure of Ca(II)-bound Gla Domain of Factor IX Complexed with Binding Protein | | Descriptor: | CALCIUM ION, Coagulation factor IX, Coagulation factor IX-binding protein B chain, ... | | Authors: | Shikamoto, Y, Morita, T, Fujimoto, Z, Mizuno, H. | | Deposit date: | 2003-01-20 | | Release date: | 2003-07-08 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Crystal Structure of Mg2+- and Ca2+-bound Gla Domain of Factor IX Complexed with Binding Protein
J.Biol.Chem., 278, 2003
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1KCG
 | | NKG2D in complex with ULBP3 | | Descriptor: | GLUTATHIONE, NKG2-D type II integral membrane protein, ULBP3 protein | | Authors: | Radaev, S, Sun, P. | | Deposit date: | 2001-11-08 | | Release date: | 2002-01-09 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Conformational plasticity revealed by the cocrystal structure of NKG2D and its class I MHC-like ligand ULBP3.
Immunity, 15, 2001
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1J34
 | | Crystal Structure of Mg(II)-and Ca(II)-bound Gla Domain of Factor IX Complexed with Binding Protein | | Descriptor: | CALCIUM ION, Coagulation factor IX, MAGNESIUM ION, ... | | Authors: | Shikamoto, Y, Morita, T, Fujimoto, Z, Mizuno, H. | | Deposit date: | 2003-01-20 | | Release date: | 2003-07-08 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | Crystal Structure of Mg2+- and Ca2+-bound Gla Domain of Factor IX Complexed with Binding Protein
J.Biol.Chem., 278, 2003
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1IOD
 | | CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN THE COAGULATION FACTOR X BINDING PROTEIN FROM SNAKE VENOM AND THE GLA DOMAIN OF FACTOR X | | Descriptor: | CALCIUM ION, COAGULATION FACTOR X BINDING PROTEIN, COAGULATION FACTOR X GLA DOMAIN | | Authors: | Mizuno, H, Fujimoto, Z, Atoda, H, Morita, T. | | Deposit date: | 2001-02-27 | | Release date: | 2001-06-27 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Crystal structure of an anticoagulant protein in complex with the Gla domain of factor X.
Proc.Natl.Acad.Sci.Usa, 98, 2001
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1IJK
 | | The von Willebrand Factor mutant (I546V) A1 domain-botrocetin Complex | | Descriptor: | Botrocetin, von Willebrand factor | | Authors: | Fukuda, K, Doggett, T.A, Bankston, L.A, Cruz, M.A, Diacovo, T.G, Liddington, R.C. | | Deposit date: | 2001-04-26 | | Release date: | 2002-07-10 | | Last modified: | 2021-10-27 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structural basis of von Willebrand factor activation by the snake toxin botrocetin.
Structure, 10, 2002
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8HBC
 | | Crystal structure of the CysR-CTLD3 fragment of human DEC205 | | Descriptor: | Lymphocyte antigen 75 | | Authors: | Kong, D, Yu, B, Hu, Z, Cheng, C, Cao, L, He, Y. | | Deposit date: | 2022-10-28 | | Release date: | 2023-11-01 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (3.35 Å) | | Cite: | Interaction of human dendritic cell receptor DEC205/CD205 with keratins.
J.Biol.Chem., 300, 2024
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7QSR
 | | CryoEM structure of the Ectodomain of Human PLA2R | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Secretory phospholipase A2 receptor, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Briggs, D.C, Lockhart-Cairns, M.P, Baldock, C. | | Deposit date: | 2022-01-14 | | Release date: | 2022-07-20 | | Last modified: | 2022-08-03 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Structure of PLA2R reveals presentation of the dominant membranous nephropathy epitope and an immunogenic patch.
Proc.Natl.Acad.Sci.USA, 119, 2022
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8K8H
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5VC1
 | | Crystal structure of L-selectin lectin/EGF domains | | Descriptor: | CALCIUM ION, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | | Authors: | Wedepohl, S, Dernedde, J, Vahedi-Faridi, A, Tauber, R, Saenger, W, Bulut, H. | | Deposit date: | 2017-03-30 | | Release date: | 2017-06-14 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.94 Å) | | Cite: | Reducing Macro- and Microheterogeneity of N-Glycans Enables the Crystal Structure of the Lectin and EGF-Like Domains of Human L-Selectin To Be Solved at 1.9 angstrom Resolution.
Chembiochem, 18, 2017
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5XTS
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5XTW
 | | Crystal structure of the CysR-CTLD2 fragment of human MR at acidic pH | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, Macrophage mannose receptor 1 | | Authors: | He, Y, Hu, Z. | | Deposit date: | 2017-06-21 | | Release date: | 2017-12-27 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Structural Insights into the pH-Dependent Conformational Change and Collagen Recognition of the Human Mannose Receptor
Structure, 26, 2018
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8G94
 | | Structure of CD69-bound S1PR1 coupled to heterotrimeric Gi | | Descriptor: | Early activation antigen CD69, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | Authors: | Chen, H, Li, X. | | Deposit date: | 2023-02-21 | | Release date: | 2023-04-19 | | Last modified: | 2023-04-26 | | Method: | ELECTRON MICROSCOPY (3.15 Å) | | Cite: | Transmembrane protein CD69 acts as an S1PR1 agonist.
Elife, 12, 2023
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6EYK
 | | E-selectin lectin, EGF-like and two SCR domains complexed with glycomimetic ligand NV355 | | Descriptor: | (2~{S})-3-cyclohexyl-2-[(2~{R},3~{S},4~{S},5~{R},6~{R})-2-(hydroxymethyl)-6-[(1~{R},2~{R},3~{S})-3-methyl-2-[(2~{R},3~{S},4~{R},5~{S},6~{R})-3,4,5-tris(oxidanyl)-6-(trifluoromethyl)oxan-2-yl]oxy-cyclohexyl]oxy-3,5-bis(oxidanyl)oxan-4-yl]oxy-propanoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | Authors: | Jakob, R.P, Zihlmann, P, Preston, R.C, Varga, N, Ernst, B, Maier, T. | | Deposit date: | 2017-11-13 | | Release date: | 2018-11-21 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.21 Å) | | Cite: | E-selectin lectin with different glycomimetic ligands
To Be Published
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6EYJ
 | | E-selectin lectin, EGF-like and two SCR domains complexed with glycomimetic ligand NV354 | | Descriptor: | (2~{S})-3-cyclohexyl-2-[(2~{R},3~{S},4~{S},5~{R},6~{R})-2-(hydroxymethyl)-3,5-bis(oxidanyl)-6-[(1~{R},2~{R})-2-[(2~{R},3~{S},4~{R},5~{S},6~{R})-3,4,5-tris(oxidanyl)-6-(trifluoromethyl)oxan-2-yl]oxycyclohexyl]oxy-oxan-4-yl]oxy-propanoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | Authors: | Jakob, R.P, Zihlmann, P, Preston, R.C, Varga, N, Ernst, B, Maier, T. | | Deposit date: | 2017-11-13 | | Release date: | 2018-11-21 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | E-selectin lectin with different glycomimetic ligands
To Be Published
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6EYI
 | | E-selectin lectin, EGF-like and two SCR domains complexed with glycomimetic ligand BW69669 | | Descriptor: | (2~{R})-3-cyclohexyl-2-[(2~{R},3~{S},4~{S},5~{R},6~{R})-2-(hydroxymethyl)-6-[(1~{R},2~{R})-2-[(2~{S},3~{S},4~{R},5~{S},6~{S})-6-methyl-3,4,5-tris(oxidanyl)oxan-2-yl]oxycyclohexyl]oxy-3,5-bis(oxidanyl)oxan-4-yl]oxy-propanoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | Authors: | Jakob, R.P, Zihlmann, P, Preston, R.C, Varga, N, Ernst, B, Maier, T. | | Deposit date: | 2017-11-13 | | Release date: | 2018-11-21 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.04 Å) | | Cite: | E-selectin lectin with different glycomimetic ligands
To Be Published
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5E4L
 | | Structure of ligand binding region of uPARAP at pH 5.3 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, C-type mannose receptor 2, CALCIUM ION | | Authors: | Yuan, C, Huang, M. | | Deposit date: | 2015-10-06 | | Release date: | 2016-10-12 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.44 Å) | | Cite: | Crystal structures of uPARAP, a member of mannose receptor family
to be published
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5E4K
 | | Structure of ligand binding region of uPARAP at pH 7.4 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL, C-type mannose receptor 2, ... | | Authors: | Yuan, C, Huang, M. | | Deposit date: | 2015-10-06 | | Release date: | 2016-08-10 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.58 Å) | | Cite: | Crystal structures of the ligand-binding region of uPARAP: effect of calcium ion binding
Biochem.J., 473, 2016
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5AO5
 | | Endo180 D1-4, monoclinic form | | Descriptor: | C-TYPE MANNOSE RECEPTOR 2, SODIUM ION, SULFATE ION | | Authors: | Paracuellos, P, Briggs, D.C, Carafoli, F, Loncar, T, Hohenester, E. | | Deposit date: | 2015-09-09 | | Release date: | 2015-10-28 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.48 Å) | | Cite: | Insights Into Collagen Uptake by C-Type Mannose Receptors from the Crystal Structure of Endo180 Domains 1-4.
Structure, 23, 2015
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