1UEX

Crystal structure of von Willebrand Factor A1 domain complexed with snake venom bitiscetin

Summary for 1UEX

• Entry DOI: 10.2210/pdb1uex/pdb
• Related: 1AUQ 1JWI
• Descriptor: bitiscetin alpha chain, bitiscetin beta chain, von Willebrand Factor, ... (4 entities in total)
• Functional Keywords: c-type lectin heterodimer, toxin-blood clotting complex, toxin/blood clotting
• Biological source: Homo sapiens (human); More
• Cellular location: Secreted: P04275
• Total number of polymer chains: 3
• Total formula weight: 53665.44

Authors

Maita, N.,Nishio, K.,Nishimoto, E.,Matsui, T.,Shikamoto, Y.,Morita, T.,Sadler, J.E.,Mizuno, H. (deposition date: 2003-05-22, release date: 2003-09-30, Last modification date: 2023-10-25)

• Primary citation: Maita, N.,Nishio, K.,Nishimoto, E.,Matsui, T.,Shikamoto, Y.,Morita, T.,Sadler, J.E.,Mizuno, H.; Crystal structure of von Willebrand factor A1 domain complexed with snake venom, bitiscetin. Insight into glycoprotein Ibalpha binding mechanism induced by snake venom proteins.; J.Biol.Chem., 278:37777-37781, 2003; PubMed: 12851390; DOI: 10.1074/jbc.M305566200

Experimental method

X-RAY DIFFRACTION (2.85 Å)