Crystal structure of NK receptor Ly49C mutant with its MHC class I ligand H-2Kb

Summary for 1P4L
Related1P1Z 1QO3 1VAC
DescriptorMHC CLASS I H-2KB HEAVY CHAIN, Beta-2-microglobulin, Ovalbumin peptide, ... (4 entities in total)
Functional Keywordsnatural killer receptor, mhc class i, c-type lectin-like domain, immune system
Biological sourceMus musculus (house mouse)
Cellular locationMembrane; Single-pass type I membrane protein: P01901
Secreted: P01887 P01012
Membrane; Single-pass type II membrane protein: Q64329
Total number of polymer chains4
Total formula weight58828.92
Dam, J.,Guan, R.,Natarajan, K.,Dimasi, N.,Mariuzza, R.A. (deposition date: 2003-04-23, release date: 2003-11-11, Last modification date: 2011-07-13)
Primary citationChlewicki, L.K.,Dam, J.,Dimasi, N.,Guan, R.,Kranz, D.M.,Margulies, D.H.,Mariuzza, R.A.,Natarajan, K.,Schuck, P.
Variable MHC class I engagement by Ly49 natural killer cell receptors demonstrated by the crystal structure of Ly49C bound to H-2K(b).
Nat.Immunol., 4:1213-1222, 2003
PubMed: 14595439
DOI: 110.1038/ni1006
PDB entries with the same primary citation
Experimental method
Structure validation
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PDB entries from 2021-06-23