4GKO

Crystal structure of the calcium2+-bound human IgE-Fc(epsilon)3-4 bound to its B cell receptor derCD23

Summary for 4GKO

Entry DOI	10.2210/pdb4gko/pdb
Related	1T8C 1T8D 2H2R 2H2T 3H9Y 3HA0 4EZM 4G96 4G9A 4GI0 4GJ0 4GJX 4GK1
Descriptor	Ig epsilon chain C region, Low affinity immunoglobulin epsilon Fc receptor, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
Functional Keywords	immunoglobulin fold lectin, antibody receptor, immune system
Biological source	Homo sapiens (human) More
Cellular location	Cell membrane; Single-pass type II membrane protein: P06734
Total number of polymer chains	12
Total formula weight	252576.51
Authors	Yuan, D.,Sutton, B.J.,Dhaliwal, B. (deposition date: 2012-08-13, release date: 2013-06-26, Last modification date: 2023-09-13)
Primary citation	Yuan, D.,Keeble, A.H.,Hibbert, R.G.,Fabiane, S.,Gould, H.J.,McDonnell, J.M.,Beavil, A.J.,Sutton, B.J.,Dhaliwal, B. Ca2+-dependent Structural Changes in the B-cell Receptor CD23 Increase Its Affinity for Human Immunoglobulin E. J.Biol.Chem., 288:21667-21677, 2013 Cited by PubMed: 23775083 DOI: 10.1074/jbc.M113.480657 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.3 Å)

Structure validation