4GKO
Crystal structure of the calcium2+-bound human IgE-Fc(epsilon)3-4 bound to its B cell receptor derCD23
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Ig epsilon chain C region | polymer | 223 | 24920.1 | 6 | UniProt (P01854) Pfam (PF07654) | Homo sapiens (human) | |
| 2 | G, H, I, J, K... (G, H, I, J, K...) | Low affinity immunoglobulin epsilon Fc receptor | polymer | 143 | 16165.0 | 6 | UniProt (P06734) Pfam (PF00059) | Homo sapiens (human) | BLAST-2, C-type lectin domain family 4 member J, Fc-epsilon-RII, Immunoglobulin E-binding factor, Lymphocyte IgE receptor, Low affinity immunoglobulin epsilon Fc receptor membrane-bound form, Low affinity immunoglobulin epsilon Fc receptor soluble form |
| 3 | M, N, O, P, Q... (M, N, O, P, Q...) | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 6 | In PDB GlyTouCan (G22768VO) | |||
| 4 | S, T (C) | alpha-D-mannopyranose | non-polymer | 180.2 | 2 | Chemie (MAN) | |||
| 5 | U, V, W, X, Y... (G, H, I, J, K...) | CALCIUM ION | non-polymer | 40.1 | 6 | Chemie (CA) |
Sequence modifications
A, B, C, D, E, F: 328 - 547 (UniProt: P01854)
| PDB | External Database | Details |
|---|---|---|
| Ala 325 | - | expression tag |
| Asp 326 | - | expression tag |
| Pro 327 | - | expression tag |
| Gln 371 | Asn 252 | conflict |
| Gln 383 | Asn 264 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 246510.8 | |
| Branched | Number of molecules | 6 |
| Total formula weight | 5464.9 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 600.8 | |
| All* | Total formula weight | 252576.5 |
