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1U0N

The ternary von Willebrand Factor A1-glycoprotein Ibalpha-botrocetin complex

Summary for 1U0N
Entry DOI10.2210/pdb1u0n/pdb
Related1AUQ 1IJB 1IJK
DescriptorVon Willebrand factor, Botrocetin, Platelet glycoprotein Ib, ... (4 entities in total)
Functional Keywordsrossmann fold, lrr motif, c-type lectin fold, protein-protein complex, blood clotting
Biological sourceHomo sapiens (human)
More
Cellular locationSecreted: P04275 P22029 P22030
Membrane; Single-pass type I membrane protein: P07359
Total number of polymer chains4
Total formula weight83531.42
Authors
Fukuda, K.,Liddington, R.C. (deposition date: 2004-07-13, release date: 2005-04-19, Last modification date: 2021-10-27)
Primary citationFukuda, K.,Doggett, T.,Laurenzi, I.J.,Liddington, R.C.,Diacovo, T.G.
The snake venom protein botrocetin acts as a biological brace to promote dysfunctional platelet aggregation
Nat.Struct.Mol.Biol., 12:152-159, 2005
Cited by
PubMed: 15665869
DOI: 10.1038/nsmb892
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.95 Å)
Structure validation

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