PDB: 9904 resultsInfo pagesStatus searchChemie searchBIRD

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6PK8	Antibody scFv-M204 dimeric state Descriptor: SULFATE ION, scFv-M204 antibody Authors: Abskharon, R, Sawaya, M.R, Seidler, P.M, Cascio, D, Eisenberg, D.S. Deposit date: 2019-06-28 Release date: 2020-06-24 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.91 Å) Cite: Crystal structure of a conformational antibody that binds tau oligomers and inhibits pathological seeding by extracts from donors with Alzheimer's disease. J.Biol.Chem., 295, 2020
6PSC	Antibody scFv-M204 trimeric state Descriptor: scFv-M204 antibody Authors: Abskharon, R, Sawaya, M.R, Seidler, P.M, Cascio, D, Eisenberg, D.S. Deposit date: 2019-07-12 Release date: 2020-06-17 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (3.6 Å) Cite: Crystal structure of a conformational antibody that binds tau oligomers and inhibits pathological seeding by extracts from donors with Alzheimer's disease. J.Biol.Chem., 295, 2020
5F6H	Crystal Structure of Tier 2 Neutralizing Antibody DH427 from a Rhesus Macaque Descriptor: DH427 Antibody Heavy Chain, DH427 Antibody Light Chain Authors: Fera, D, Harrison, S.C. Deposit date: 2015-12-06 Release date: 2016-01-13 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.66 Å) Cite: Structural Constraints of Vaccine-Induced Tier-2 Autologous HIV Neutralizing Antibodies Targeting the Receptor-Binding Site. Cell Rep, 14, 2016
5F6J	Crystal Structure of Tier 2 Neutralizing Antibody DH427 from a Rhesus Macaque in Complex with HIV-1 gp120 Core Descriptor: DH427 Antibody Heavy Chain, DH427 Antibody Light Chain, ENVELOPE GLYCOPROTEIN GP120 of HIV-1 clade C Authors: Fera, D, Harrison, S.C. Deposit date: 2015-12-06 Release date: 2016-01-13 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (6.63 Å) Cite: Structural Constraints of Vaccine-Induced Tier-2 Autologous HIV Neutralizing Antibodies Targeting the Receptor-Binding Site. Cell Rep, 14, 2016
4F58	Fab structure of a neutralizing antibody L3 from an early subtype A HIV-1 infected patient Descriptor: Heavy chain of Fab of a neutralizing antibody L3, Light chain of Fab of a neutralizing antibody L3, SULFATE ION Authors: Pan, R.M, Kong, X.P. Deposit date: 2012-05-12 Release date: 2013-03-27 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.488 Å) Cite: Viral Escape from Neutralizing Antibodies in Early Subtype A HIV-1 Infection Drives an Increase in Autologous Neutralization Breadth. Plos Pathog., 9, 2013
1H3P	STRUCTURAL CHARACTERISATION OF A MONOCLONAL ANTIBODY SPECIFIC FOR THE PRES1 REGION OF THE HEPATITIS B VIRUS Descriptor: ANTIBODY FAB FRAGMENT Authors: Pizarro, J.C, Vulliez-Le-normand, B, Riottot, M.M, Budkowska, A, Bentley, G.A. Deposit date: 2002-09-12 Release date: 2002-09-19 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Structural and Functional Characterisation of a Monoclonal Antibody Specific for the Pres1 Region of Hepatitis B Virus FEBS Lett., 509, 2001
3HAE	Rational development of high-affinity T-cell receptor-like antibodies Descriptor: Antibody heavy chain, Antibody light chain, Beta-2-microglobulin, ... Authors: Stewart-Jones, G, Wadle, A, Hombach, A, Shenderov, E, Held, G, Fischer, E. Deposit date: 2009-05-01 Release date: 2009-05-19 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Rational development of high-affinity T-cell receptor-like antibodies Proc.Natl.Acad.Sci.USA, 106, 2009
4F57	Fab structure of a neutralizing antibody L1 from an early subtype A HIV-1 infected patient Descriptor: GLYCEROL, Heavy chain of Fab of a neutralizing antibody L1, Light chain of Fab of a neutralizing antibody L1 Authors: Pan, R.M, Kong, X.P. Deposit date: 2012-05-12 Release date: 2013-03-27 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Viral Escape from Neutralizing Antibodies in Early Subtype A HIV-1 Infection Drives an Increase in Autologous Neutralization Breadth. Plos Pathog., 9, 2013
3GJF	Rational development of high-affinity T-cell receptor-like antibodies Descriptor: Antibody heavy chain, Antibody light chain, Beta-2-microglobulin, ... Authors: Stewart-Jones, G, Wadle, A, Hombach, A, Shenderov, E, Held, G, Fischer, E, Kleber, S, Stenner-Liewen, F, Bauer, S, McMichael, A, Knuth, A, Abken, H, Hombach, A.A, Cerundolo, V, Jones, E.Y, Renner, C. Deposit date: 2009-03-08 Release date: 2009-04-28 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Rational development of high-affinity T-cell receptor-like antibodies Proc.Natl.Acad.Sci.USA, 106, 2009
3G5X	Antibodies Specifically Targeting a Locally Misfolded Region of Tumor Associated EGFR Descriptor: 806 heavy chain, 806 light chain Authors: Garrett, T.P.J, Burgess, A.W. Deposit date: 2009-02-05 Release date: 2009-12-15 Last modified: 2011-10-12 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Antibodies specifically targeting a locally misfolded region of tumor associated EGFR Proc.Natl.Acad.Sci.USA, 106, 2009
3G5V	Antibodies Specifically Targeting a Locally Misfolded Region of Tumor Associated EGFR Descriptor: 806 light chain, 808 heavy chain, ACETATE ION, ... Authors: Garrett, T.P.J, Burgess, A.W, Huyton, T, Xu, Y. Deposit date: 2009-02-05 Release date: 2010-02-09 Last modified: 2011-10-12 Method: X-RAY DIFFRACTION (2.001 Å) Cite: Antibodies specifically targeting a locally misfolded region of tumor associated EGFR Proc.Natl.Acad.Sci.USA, 106, 2009
7QT0	Antibody FenAb136 - fentanyl complex Descriptor: 2-[2-[2-[2-[[5-oxidanylidene-5-[2-[4-[phenyl(propanoyl)amino]piperidin-1-yl]ethylamino]pentanoyl]amino]ethanoylamino]ethanoylamino]ethanoylamino]ethanoic acid, Antibody heavy chain, Antibody light chain Authors: Zeelen, J.P, Straaten van, M, Stebbins, C.E. Deposit date: 2022-01-14 Release date: 2023-05-24 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.07 Å) Cite: A trypanosome-derived immunotherapeutics platform elicits potent high-affinity antibodies, negating the effects of the synthetic opioid fentanyl. Cell Rep, 42, 2023
7QT4	Antibody FenAb709 - fentanyl complex Descriptor: 2-[2-[2-[2-[[5-oxidanylidene-5-[2-[4-[phenyl(propanoyl)amino]piperidin-1-yl]ethylamino]pentanoyl]amino]ethanoylamino]ethanoylamino]ethanoylamino]ethanoic acid, Antibody heavy chain, Antibody light chain Authors: Zeelen, J.P, Straaten van, M, Stebbins, C.E. Deposit date: 2022-01-14 Release date: 2023-05-24 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.32 Å) Cite: A trypanosome-derived immunotherapeutics platform elicits potent high-affinity antibodies, negating the effects of the synthetic opioid fentanyl. Cell Rep, 42, 2023
3G5Z	Antibodies Specifically Targeting a Locally Misfolded Region of Tumor Associated EGFR Descriptor: 175 heavy chain, 175 light chain Authors: Garrett, T.P.J, Burgess, A.W. Deposit date: 2009-02-05 Release date: 2010-02-09 Last modified: 2011-10-12 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Antibodies specifically targeting a locally misfolded region of tumor associated EGFR Proc.Natl.Acad.Sci.USA, 106, 2009
3G5Y	Antibodies Specifically Targeting a Locally Misfolded Region of Tumor Associated EGFR Descriptor: 175 heavy chain, 175 light chain, EGFR peptide Authors: Garrett, T.P.J, Burgess, A.W. Deposit date: 2009-02-05 Release date: 2010-02-09 Last modified: 2011-10-12 Method: X-RAY DIFFRACTION (1.59 Å) Cite: Antibodies specifically targeting a locally misfolded region of tumor associated EGFR Proc.Natl.Acad.Sci.USA, 106, 2009
5FHA	Crystal Structure of Protective Ebola Virus Antibody 114 Descriptor: Antibody 114 Fab heavy chain, Antibody 114 Fab light chain Authors: Gilman, M.S.A, McLellan, J.S. Deposit date: 2015-12-21 Release date: 2016-03-16 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.973 Å) Cite: Structural and molecular basis for Ebola virus neutralization by protective human antibodies. Science, 351, 2016
6OAN	Structure of DBP in complex with human neutralizing antibody 053054 Descriptor: Antibody 053054 single chain variable fragment, Duffy binding surface protein region II, SULFATE ION Authors: Urusova, D, Tolia, N.H. Deposit date: 2019-03-18 Release date: 2019-06-12 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Structural basis for neutralization of Plasmodium vivax by naturally acquired human antibodies that target DBP. Nat Microbiol, 4, 2019
6OAO	Structure of DBP in complex with human neutralizing antibody 092096 Descriptor: Antibody 092096 single chain variable fragment, Duffy binding surface protein region II, SULFATE ION Authors: Urusova, D, Tolia, N.H. Deposit date: 2019-03-18 Release date: 2019-06-12 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (3.497 Å) Cite: Structural basis for neutralization of Plasmodium vivax by naturally acquired human antibodies that target DBP. Nat Microbiol, 4, 2019
5W3P	ANTIBODY C706 IN COMPLEX WTH BETA-AMYLOID PEPTIDE 1-16 Descriptor: Amyloid beta A4 protein, Antibody C706 Fab HEAVY CHAIN, Antibody C706 Fab LIGHT CHAIN, ... Authors: Teplyakov, A, Obmolova, G, Gilliland, G.L. Deposit date: 2017-06-08 Release date: 2017-09-20 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.92 Å) Cite: A coiled conformation of amyloid-beta recognized by antibody C706. Alzheimers Res Ther, 9, 2017
5UY3	Crystal structure of human Fab PGT144, a broadly reactive and potent HIV-1 neutralizing antibody Descriptor: Antibody PGT144 Fab heavy chain, Antibody PGT144 Fab light chain Authors: Julien, J.-P, Lee, J.H, Wilson, I.A. Deposit date: 2017-02-23 Release date: 2017-04-19 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2.9 Å) Cite: A Broadly Neutralizing Antibody Targets the Dynamic HIV Envelope Trimer Apex via a Long, Rigidified, and Anionic beta-Hairpin Structure. Immunity, 46, 2017
6AZM	Crystal structure of the 580 germline antibody bound to circumsporozoite protein NANP 5-mer Descriptor: 580 germline antibody, heavy chain, light chain, ... Authors: Scally, S.W, Bosch, A, Triller, G, Wardemann, H, Julien, J.P. Deposit date: 2017-09-11 Release date: 2017-12-13 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Natural Parasite Exposure Induces Protective Human Anti-Malarial Antibodies. Immunity, 47, 2017
6B0S	Crystal structure of circumsporozoite protein aTSR domain in complex with 1710 antibody Descriptor: 1710 antibody, heavy chain, light chain, ... Authors: Scally, S.W, Murugan, R, Bosch, A, Triller, G, Wardemann, H, Julien, J.P. Deposit date: 2017-09-15 Release date: 2017-11-08 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Rare PfCSP C-terminal antibodies induced by live sporozoite vaccination are ineffective against malaria infection. J. Exp. Med., 215, 2018
1AD0	FAB FRAGMENT OF ENGINEERED HUMAN MONOCLONAL ANTIBODY A5B7 Descriptor: ANTIBODY A5B7 (HEAVY CHAIN), ANTIBODY A5B7 (LIGHT CHAIN) Authors: Banfield, M.J, Brady, R.L. Deposit date: 1997-02-19 Release date: 1998-02-25 Last modified: 2023-08-02 Method: X-RAY DIFFRACTION (2.5 Å) Cite: VL:VH domain rotations in engineered antibodies: crystal structures of the Fab fragments from two murine antitumor antibodies and their engineered human constructs. Proteins, 29, 1997
5VYF	Structure of single chain Fel d 1 bound to a neutralizing antibody Descriptor: Antibody Fab heavy chain, Antibody light chain, CALCIUM ION, ... Authors: Franklin, M.C. Deposit date: 2017-05-25 Release date: 2018-04-04 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Treating cat allergy with monoclonal IgG antibodies that bind allergen and prevent IgE engagement. Nat Commun, 9, 2018
7U8M	Crystal structure of chimeric hemagglutinin cH15/3 in complex with broad protective antibodies 31.a.83 and FluA-20 Descriptor: Antibody 31.a.83 Fab light chain, antibody 31.a.83 Fab heavy chain, antibody FluA-20 Fab heavy chain, ... Authors: Zhu, X, Wilson, I.A. Deposit date: 2022-03-08 Release date: 2022-06-08 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (5.39 Å) Cite: Influenza chimeric hemagglutinin structures in complex with broadly protective antibodies to the stem and trimer interface. Proc.Natl.Acad.Sci.USA, 119, 2022

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