6B0S

Crystal structure of circumsporozoite protein aTSR domain in complex with 1710 antibody

Summary for 6B0S

• Entry DOI: 10.2210/pdb6b0s/pdb
• Descriptor: 1710 antibody, heavy chain, 1710 antibody, light chain, Circumsporozoite protein, ... (6 entities in total)
• Functional Keywords: malaria, circumsporozoite protein, alpha thrombospondin type-1 repeat, immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 3
• Total formula weight: 56522.85

Authors

Scally, S.W.,Murugan, R.,Bosch, A.,Triller, G.,Wardemann, H.,Julien, J.P. (deposition date: 2017-09-15, release date: 2017-11-08, Last modification date: 2023-10-04)

• Primary citation: Scally, S.W.,Murugan, R.,Bosch, A.,Triller, G.,Costa, G.,Mordmuller, B.,Kremsner, P.G.,Sim, B.K.L.,Hoffman, S.L.,Levashina, E.A.,Wardemann, H.,Julien, J.P.; Rare PfCSP C-terminal antibodies induced by live sporozoite vaccination are ineffective against malaria infection.; J. Exp. Med., 215:63-75, 2018; PubMed: 29167197; DOI: 10.1084/jem.20170869

Experimental method

X-RAY DIFFRACTION (1.95 Å)