6B0S

Crystal structure of circumsporozoite protein aTSR domain in complex with 1710 antibody

Functional Information from GO Data

Chain	GOid	namespace	contents
C	0009986	cellular_component	cell surface

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	binding site for residue GOL H 301

Chain	Residue
H	LEU45
H	GLU46
H	HOH511
H	HOH516
L	PHE98

---

site_id	AC2
Number of Residues	5
Details	binding site for residue GOL H 302

Chain	Residue
H	HOH503
H	TYR32
H	ARG94
H	GLY174
H	HOH433

---

site_id	AC3
Number of Residues	3
Details	binding site for residue GOL H 303

Chain	Residue
H	ASN155
H	ALA158
H	GLN192

---

site_id	AC4
Number of Residues	6
Details	binding site for residue GOL L 301

Chain	Residue
L	ALA151
L	ASP152
L	SER154
L	HIS189
L	HOH408
L	HOH439

---

site_id	AC5
Number of Residues	7
Details	binding site for residue GOL C 401

Chain	Residue
C	SER328
C	THR329
C	ALA351
C	LYS353
C	LYS355
C	HOH513
L	HOH458

---

site_id	AC6
Number of Residues	6
Details	binding site for residue IPA C 402

Chain	Residue
C	LYS353
C	GLU357
C	ASP359
C	ASN362
C	ASP363
H	TYR56

---

Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YSCQVTH

Chain	Residue	Details
L	TYR192-HIS198
H	TYR194-HIS200

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Lipidation: {"description":"GPI-anchor amidated cysteine","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	Glycosylation: {"description":"O-linked (Fuc) threonine","evidences":[{"source":"PubMed","id":"27128092","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"28916755","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---