5UY3
Crystal structure of human Fab PGT144, a broadly reactive and potent HIV-1 neutralizing antibody
Summary for 5UY3
| Entry DOI | 10.2210/pdb5uy3/pdb |
| Related | 3U1S 4RQQ |
| Descriptor | Antibody PGT144 Fab light chain, Antibody PGT144 Fab heavy chain (2 entities in total) |
| Functional Keywords | antibody, hiv env glycoprotein, immune system |
| Biological source | Homo sapiens More |
| Total number of polymer chains | 4 |
| Total formula weight | 98870.10 |
| Authors | Julien, J.-P.,Lee, J.H.,Wilson, I.A. (deposition date: 2017-02-23, release date: 2017-04-19, Last modification date: 2023-11-15) |
| Primary citation | Lee, J.H.,Andrabi, R.,Su, C.Y.,Yasmeen, A.,Julien, J.P.,Kong, L.,Wu, N.C.,McBride, R.,Sok, D.,Pauthner, M.,Cottrell, C.A.,Nieusma, T.,Blattner, C.,Paulson, J.C.,Klasse, P.J.,Wilson, I.A.,Burton, D.R.,Ward, A.B. A Broadly Neutralizing Antibody Targets the Dynamic HIV Envelope Trimer Apex via a Long, Rigidified, and Anionic beta-Hairpin Structure. Immunity, 46:690-702, 2017 Cited by PubMed: 28423342DOI: 10.1016/j.immuni.2017.03.017 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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