5F6J
Crystal Structure of Tier 2 Neutralizing Antibody DH427 from a Rhesus Macaque in Complex with HIV-1 gp120 Core
Summary for 5F6J
Entry DOI | 10.2210/pdb5f6j/pdb |
Descriptor | ENVELOPE GLYCOPROTEIN GP120 of HIV-1 clade C, DH427 Antibody Light Chain, DH427 Antibody Heavy Chain (3 entities in total) |
Functional Keywords | fab fragment, hiv-1, antibody, viral protein-immue system complex, viral protein/immue system |
Biological source | Human immunodeficiency virus 1 More |
Total number of polymer chains | 6 |
Total formula weight | 172529.24 |
Authors | Fera, D.,Harrison, S.C. (deposition date: 2015-12-06, release date: 2016-01-13, Last modification date: 2023-09-27) |
Primary citation | Bradley, T.,Fera, D.,Bhiman, J.,Eslamizar, L.,Lu, X.,Anasti, K.,Zhang, R.,Sutherland, L.L.,Scearce, R.M.,Bowman, C.M.,Stolarchuk, C.,Lloyd, K.E.,Parks, R.,Eaton, A.,Foulger, A.,Nie, X.,Karim, S.S.,Barnett, S.,Kelsoe, G.,Kepler, T.B.,Alam, S.M.,Montefiori, D.C.,Moody, M.A.,Liao, H.X.,Morris, L.,Santra, S.,Harrison, S.C.,Haynes, B.F. Structural Constraints of Vaccine-Induced Tier-2 Autologous HIV Neutralizing Antibodies Targeting the Receptor-Binding Site. Cell Rep, 14:43-54, 2016 Cited by PubMed: 26725118DOI: 10.1016/j.celrep.2015.12.017 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (6.63 Å) |
Structure validation
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