5F6J
Crystal Structure of Tier 2 Neutralizing Antibody DH427 from a Rhesus Macaque in Complex with HIV-1 gp120 Core
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | G, E | ENVELOPE GLYCOPROTEIN GP120 of HIV-1 clade C | polymer | 352 | 39031.2 | 2 | UniProt (R4GRV3) Pfam (PF00516) In PDB | Human immunodeficiency virus 1 | |
2 | A, F | DH427 Antibody Light Chain | polymer | 216 | 22858.2 | 2 | Macaca mulatta | ||
3 | B, H | DH427 Antibody Heavy Chain | polymer | 228 | 24375.2 | 2 | Macaca mulatta |
Sequence modifications
G, E: 44 - 492 (UniProt: R4GRV3)
PDB | External Database | Details |
---|---|---|
Lys 458 | Gly 321 | engineered mutation |
- | Gly 322 | deletion |
- | Asn 323 | deletion |
- | Asp 324 | deletion |
Ser 463 | Asn 326 | engineered mutation |
Asn 464 | Asp 327 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 172529.2 | |
All* | Total formula weight | 172529.2 |