3HAE

Rational development of high-affinity T-cell receptor-like antibodies

Replaces:  3GJG
Summary for 3HAE
Related3GJE 3GJF
DescriptorHLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, NYESO-1 peptide, ... (5 entities in total)
Functional Keywordsfab, major histocompatability complex, immunity, disulfide bond, glycoprotein, host-virus interaction, immune response, membrane, mhc i, phosphoprotein, transmembrane, disease mutation, glycation, immunoglobulin domain, pyrrolidone carboxylic acid, secreted, immune system
Biological sourceHomo sapiens (human)
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Cellular locationMembrane; Single-pass type I membrane protein: P01892
Secreted: P61769
Total number of polymer chains20
Total formula weight362219.02
Authors
Stewart-Jones, G.,Wadle, A.,Hombach, A.,Shenderov, E.,Held, G.,Fischer, E. (deposition date: 2009-05-01, release date: 2009-05-19, Last modification date: 2011-07-13)
Primary citationAbken, H.,Bauer, S.,Cerundolo, V.,Fischer, E.,Held, G.,Hombach, A.,Hombach, A.A.,Jones, E.Y.,Kleber, S.,Knuth, A.,McMichael, A.,Renner, C.,Shenderov, E.,Stenner-Liewen, F.,Stewart-Jones, G.,Wadle, A.
Rational development of high-affinity T-cell receptor-like antibodies
Proc.Natl.Acad.Sci.USA, 106:5784-5788, 2009
PubMed: 19307587
DOI: 110.1073/pnas.0901425106
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.9 Å)
Structure validation
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PDB entries from 2021-06-23