3G5Z
Antibodies Specifically Targeting a Locally Misfolded Region of Tumor Associated EGFR
Summary for 3G5Z
Entry DOI | 10.2210/pdb3g5z/pdb |
Descriptor | 175 light chain, 175 heavy chain (3 entities in total) |
Functional Keywords | antibody, immune system |
Biological source | Mus musculus (mouse) More |
Total number of polymer chains | 2 |
Total formula weight | 46577.37 |
Authors | Garrett, T.P.J.,Burgess, A.W. (deposition date: 2009-02-05, release date: 2010-02-09, Last modification date: 2011-10-12) |
Primary citation | Garrett, T.P.J.,Burgess, A.W.,Gan, H.K.,Luwor, R.B.,Cartwright, G.,Walker, F.,Orchard, S.G.,Clayton, A.H.A.,Nice, E.C.,Rothacker, J.,Catimel, B.,Cavenee, W.K.,Old, L.J.,Stockert, E.,Ritter, G.,Adams, T.E.,Hoyne, P.A.,Wittrup, D.,Chao, G.,Cochran, J.R.,Luo, C.,Lou, M.,Huyton, T.,Xu, Y.,Fairlie, W.D.,Yao, S.,Scott, A.M.,Johns, T.G. Antibodies specifically targeting a locally misfolded region of tumor associated EGFR Proc.Natl.Acad.Sci.USA, 106:5082-5087, 2009 Cited by PubMed: 19289842DOI: 10.1073/pnas.0811559106 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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