6AZM

Crystal structure of the 580 germline antibody bound to circumsporozoite protein NANP 5-mer

Summary for 6AZM

• Entry DOI: 10.2210/pdb6azm/pdb
• Descriptor: 580 germline antibody, light chain, 580 germline antibody, heavy chain, Circumsporozoite protein NANP 5-mer, ... (5 entities in total)
• Functional Keywords: malaria, circumsporozoite protein, fab, immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 6
• Total formula weight: 99385.81

Authors

Scally, S.W.,Bosch, A.,Triller, G.,Wardemann, H.,Julien, J.P. (deposition date: 2017-09-11, release date: 2017-12-13, Last modification date: 2024-04-03)

• Primary citation: Triller, G.,Scally, S.W.,Costa, G.,Pissarev, M.,Kreschel, C.,Bosch, A.,Marois, E.,Sack, B.K.,Murugan, R.,Salman, A.M.,Janse, C.J.,Khan, S.M.,Kappe, S.H.I.,Adegnika, A.A.,Mordmuller, B.,Levashina, E.A.,Julien, J.P.,Wardemann, H.; Natural Parasite Exposure Induces Protective Human Anti-Malarial Antibodies.; Immunity, 47:1197-1209.e10, 2017; PubMed: 29195810; DOI: 10.1016/j.immuni.2017.11.007

Experimental method

X-RAY DIFFRACTION (1.6 Å)