3G5X

Antibodies Specifically Targeting a Locally Misfolded Region of Tumor Associated EGFR

Summary for 3G5X

• Entry DOI: 10.2210/pdb3g5x/pdb
• Descriptor: 806 light chain, 806 heavy chain (3 entities in total)
• Functional Keywords: antibody, immune system
• Biological source: Mus musculus (mouse); More
• Total number of polymer chains: 4
• Total formula weight: 93601.40

Authors

Garrett, T.P.J.,Burgess, A.W. (deposition date: 2009-02-05, release date: 2009-12-15, Last modification date: 2011-10-12)

• Primary citation: Garrett, T.P.J.,Burgess, A.W.,Gan, H.K.,Luwor, R.B.,Cartwright, G.,Walker, F.,Orchard, S.G.,Clayton, A.H.A.,Nice, E.C.,Rothacker, J.,Catimel, B.,Cavenee, W.K.,Old, L.J.,Stockert, E.,Ritter, G.,Adams, T.E.,Hoyne, P.A.,Wittrup, D.,Chao, G.,Cochran, J.R.,Luo, C.,Lou, M.,Huyton, T.,Xu, Y.,Fairlie, W.D.,Yao, S.,Scott, A.M.,Johns, T.G.; Antibodies specifically targeting a locally misfolded region of tumor associated EGFR; Proc.Natl.Acad.Sci.USA, 106:5082-5087, 2009; PubMed: 19289842; DOI: 10.1073/pnas.0811559106

Experimental method

X-RAY DIFFRACTION (2.3 Å)