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2AST
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BU of 2ast by Molmil
Crystal structure of Skp1-Skp2-Cks1 in complex with a p27 peptide
Descriptor: BENZAMIDINE, Cyclin-dependent kinase inhibitor 1B, Cyclin-dependent kinases regulatory subunit 1, ...
Authors:Hao, B, Zhang, N, Schulman, B.A, Wu, G, Pagano, M, Pavletich, N.P.
Deposit date:2005-08-24
Release date:2005-10-18
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural Basis of the Cks1-Dependent Recognition of p27(Kip1) by the SCF(Skp2) Ubiquitin Ligase.
Mol.Cell, 20, 2005
2L7F
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BU of 2l7f by Molmil
Solution Structure of the Pitx2 Homeodomain
Descriptor: Pituitary homeobox 2
Authors:Doerdelmann, T, Rance, M, Baird-Titus, J.M, Kojetin, D.J.
Deposit date:2010-12-08
Release date:2011-12-14
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Solution Structure of the Pitx2 Homeodomain
To be Published
6H5H
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BU of 6h5h by Molmil
A computationally designed dRP lyase domain reconstructed from two heterologous fragments
Descriptor: polb4
Authors:ElGamacy, M, Coles, M, Lupas, A.N.
Deposit date:2018-07-24
Release date:2018-12-12
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Asymmetric protein design from conserved supersecondary structures.
J. Struct. Biol., 204, 2018
2K40
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BU of 2k40 by Molmil
NMR structure of HESX-1 homeodomain double mutant R31L/E42L
Descriptor: Homeobox expressed in ES cells 1
Authors:Asensio, J, Torrado, M, Gonzalez, C, Bastida, A.
Deposit date:2008-05-26
Release date:2009-05-05
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:The role of conserved salt-bridges on homeodomain stability
To be Published
2L7M
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BU of 2l7m by Molmil
Solution Structure of the Pitx2 Homeodomain R24H mutant
Descriptor: Pituitary homeobox 2
Authors:Doerdelmann, T, Rance, M, Kojetin, D.J, Baird-Titus, J.M.
Deposit date:2010-12-14
Release date:2011-12-14
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Solution Structure of the Pitx2 Homeodomain R24H mutant
To be Published
2LKX
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BU of 2lkx by Molmil
NMR structure of the homeodomain of Pitx2 in complex with a TAATCC DNA binding site
Descriptor: DNA (5'-D(*CP*GP*GP*GP*GP*AP*TP*TP*AP*GP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*CP*TP*AP*AP*TP*CP*CP*CP*CP*G)-3'), Pituitary homeobox 3
Authors:Baird-Titus, J.M, Doerdelmann, T, Chaney, B.A, Clark-Baldwin, K, Dave, V, Ma, J.
Deposit date:2011-10-21
Release date:2012-05-02
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Solution structure of the K50 class homeodomain PITX2 bound to DNA and implications for mutations that cause Rieger syndrome
Biochemistry, 44, 2005
2KG4
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BU of 2kg4 by Molmil
Three-dimensional structure of human Gadd45alpha in solution by NMR
Descriptor: Growth arrest and DNA-damage-inducible protein GADD45 alpha
Authors:Sanchez, R, Pantoja-Uceda, D, Prieto, J, Diercks, T, Campos-Olivas, R, Blanco, F.J.
Deposit date:2009-03-04
Release date:2009-03-31
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Solution structure of human growth arrest and DNA damage 45alpha (Gadd45alpha) and its interactions with proliferating cell nuclear antigen (PCNA) and Aurora A kinase
J.Biol.Chem., 285, 2010
2E31
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BU of 2e31 by Molmil
Structural basis for selection of glycosylated substrate by SCFFbs1 ubiquitin ligase
Descriptor: F-box only protein 2, S-phase kinase-associated protein 1A
Authors:Mizushima, T, Yoshida, Y, Kumanomidou, T, Hasegawa, Y, Yamane, T, Tanaka, K.
Deposit date:2006-11-20
Release date:2007-03-20
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis for the selection of glycosylated substrates by SCFFbs1 ubiquitin ligase
Proc.Natl.Acad.Sci.Usa, 104, 2007
1LDK
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BU of 1ldk by Molmil
Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF Ubiquitin Ligase Complex
Descriptor: CULLIN HOMOLOG, CYCLIN A/CDK2-ASSOCIATED PROTEIN P19, SKP2-like protein type gamma, ...
Authors:Zheng, N, Schulman, B.A, Song, L, Miller, J.J, Jeffrey, P.D, Wang, P, Chu, C, Koepp, D.M, Elledge, S.J, Pagano, M, Conaway, R.C, Conaway, J.W, Harper, J.W, Pavletich, N.P.
Deposit date:2002-04-08
Release date:2002-05-08
Last modified:2019-11-20
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex.
Nature, 416, 2002
6BVA
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BU of 6bva by Molmil
Ubiquitin Variant (UbV.Fl10.1) bound to a human Skp1-Fbl10 fragment complex.
Descriptor: Lysine-specific demethylase 2B, Polyubiquitin-B, S-phase kinase-associated protein 1
Authors:Manczyk, N, Sicheri, F.
Deposit date:2017-12-12
Release date:2018-07-18
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.66 Å)
Cite:A Structure-Based Strategy for Engineering Selective Ubiquitin Variant Inhibitors of Skp1-Cul1-F-Box Ubiquitin Ligases.
Structure, 26, 2018
6BYH
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BU of 6byh by Molmil
Ubiquitin Variant (UbV.Fl11.1) bound to a human Skp1-Fbl11 fragment complex.
Descriptor: Lysine-specific demethylase 2A, Polyubiquitin-B, S-phase kinase-associated protein 1
Authors:Manczyk, N, Sicheri, F.
Deposit date:2017-12-20
Release date:2018-07-18
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.61 Å)
Cite:A Structure-Based Strategy for Engineering Selective Ubiquitin Variant Inhibitors of Skp1-Cul1-F-Box Ubiquitin Ligases.
Structure, 26, 2018
4F8C
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BU of 4f8c by Molmil
Structure of the Cif:Nedd8 complex - Yersinia pseudotuberculosis Cycle Inhibiting Factor in complex with human Nedd8
Descriptor: 1,2-ETHANEDIOL, Cycle Inhibiting Factor, NEDD8
Authors:Crow, A, Banfield, M.
Deposit date:2012-05-17
Release date:2012-06-20
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:The molecular basis of Nedd8 deamidation by the bacterial effector protein Cif
Proc.Natl.Acad.Sci.USA, 2012
6C16
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BU of 6c16 by Molmil
Ubiquitin variant (UbV.Fbl10.1) bound to a human Skp1-Fbl11 fragment complex.
Descriptor: Lysine-specific demethylase 2A, Polyubiquitin-B, S-phase kinase-associated protein 1
Authors:Manczyk, N, Sicheri, F.
Deposit date:2018-01-04
Release date:2018-07-18
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.27 Å)
Cite:A Structure-Based Strategy for Engineering Selective Ubiquitin Variant Inhibitors of Skp1-Cul1-F-Box Ubiquitin Ligases.
Structure, 26, 2018
6WNX
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BU of 6wnx by Molmil
FBXW11-SKP1 in complex with a pSer33/pSer37 Beta-Catenin peptide
Descriptor: Catenin beta-1, F-box/WD repeat-containing protein 11, GLYCEROL, ...
Authors:Ivanochko, D, Edwards, A.M, Bountra, C, Arrowsmith, C.H, Boettcher, J, Structural Genomics Consortium (SGC)
Deposit date:2020-04-23
Release date:2020-05-06
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:FBXW11-SKP1 in complex with a pSer33/pSer37 Beta-Catenin peptide
To Be Published
2E32
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BU of 2e32 by Molmil
Structural basis for selection of glycosylated substrate by SCFFbs1 ubiquitin ligase
Descriptor: F-box only protein 2, S-phase kinase-associated protein 1A
Authors:Mizushima, T, Yoshida, Y, Kumanomidou, T, Hasegawa, Y, Yamane, T, Tanaka, K.
Deposit date:2006-11-20
Release date:2007-03-20
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3.52 Å)
Cite:Structural basis for the selection of glycosylated substrates by SCFFbs1 ubiquitin ligase
Proc.Natl.Acad.Sci.Usa, 104, 2007
6AC7
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BU of 6ac7 by Molmil
Structure of a (3+1) hybrid G-quadruplex in the PARP1 promoter
Descriptor: 5'-D(*TP*GP*GP*GP*GP*TP*CP*CP*GP*AP*GP*GP*CP*GP*GP*GP*GP*CP*TP*TP*GP*GP*G)-3'
Authors:Sengar, A, Vandana, J.J, Chambers, V.S, Di Antonio, M, Winnerdy, F.R, Balasubramanian, S, Phan, A.T.
Deposit date:2018-07-25
Release date:2019-02-27
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structure of a (3+1) hybrid G-quadruplex in the PARP1 promoter.
Nucleic Acids Res., 47, 2019
3L2O
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BU of 3l2o by Molmil
Structure-Based Mechanism of Dimerization-Dependent Ubiquitination by the SCFFbx4 Ubiquitin Ligase
Descriptor: F-box only protein 4, S-phase kinase-associated protein 1
Authors:Li, Y, Hao, B.
Deposit date:2009-12-15
Release date:2010-02-23
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis of dimerization-dependent ubiquitination by the SCF(Fbx4) ubiquitin ligase.
J.Biol.Chem., 285, 2010
2OVQ
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BU of 2ovq by Molmil
Structure of the Skp1-Fbw7-CyclinEdegC complex
Descriptor: F-box/WD repeat protein 7, S-phase kinase-associated protein 1A, SULFATE ION, ...
Authors:Hao, B, Oehlmann, S, Sowa, M.E, Harper, J.W, Pavletich, N.P.
Deposit date:2007-02-14
Release date:2007-04-24
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of a Fbw7-Skp1-Cyclin E Complex: Multisite-Phosphorylated Substrate Recognition by SCF Ubiquitin Ligases
Mol.Cell, 26, 2007
2OVP
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BU of 2ovp by Molmil
Structure of the Skp1-Fbw7 complex
Descriptor: F-box/WD repeat protein 7, S-phase kinase-associated protein 1A
Authors:Hao, B, Oehlmann, S, Sowa, M.E, Harper, J.W, Pavletich, N.P.
Deposit date:2007-02-14
Release date:2007-04-24
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure of a Fbw7-Skp1-Cyclin E Complex: Multisite-Phosphorylated Substrate Recognition by SCF Ubiquitin Ligases
Mol.Cell, 26, 2007
2OVR
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BU of 2ovr by Molmil
Structure of the Skp1-Fbw7-CyclinEdegN complex
Descriptor: F-box/WD repeat protein 7, S-phase kinase-associated protein 1A, SULFATE ION, ...
Authors:Hao, B, Oehlmann, S, Sowa, M.E, Harper, J.W, Pavletich, N.P.
Deposit date:2007-02-14
Release date:2007-04-24
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of a Fbw7-Skp1-Cyclin E Complex: Multisite-Phosphorylated Substrate Recognition by SCF Ubiquitin Ligases
Mol.Cell, 26, 2007
3BUY
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BU of 3buy by Molmil
MHC-I in complex with peptide
Descriptor: Beta-2-microglobulin, H-2 class I histocompatibility antigen, D-B alpha chain, ...
Authors:Rossjohn, J, La Gruta, N.L, Purcell, A.W, Turner, S.J, Dunstone, M.A.
Deposit date:2008-01-03
Release date:2008-03-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Epitope-specific TCRbeta repertoire diversity imparts no functional advantage on the CD8+ T cell response to cognate viral peptides
Proc.Natl.Acad.Sci.Usa, 105, 2008
5V4B
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BU of 5v4b by Molmil
Crystal structure of the Skp1-FBXW7-DISC1 complex
Descriptor: DISC1 peptide, F-box/WD repeat-containing protein 7, IMIDAZOLE, ...
Authors:Li, Y, Baillie, G.S, Hao, B.
Deposit date:2017-03-08
Release date:2017-09-20
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:FBXW7 regulates DISC1 stability via the ubiquitin-proteosome system.
Mol. Psychiatry, 23, 2018
5VZT
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BU of 5vzt by Molmil
Crystal structure of the Skp1-FBXO31 complex
Descriptor: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, F-box only protein 31, PHOSPHATE ION, ...
Authors:Li, Y, Jin, K, Hao, B.
Deposit date:2017-05-29
Release date:2018-01-17
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural basis of the phosphorylation-independent recognition of cyclin D1 by the SCFFBXO31 ubiquitin ligase.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5VZU
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BU of 5vzu by Molmil
Crystal structure of the Skp1-FBXO31-cyclin D1 complex
Descriptor: Cyclin D1, F-box only protein 31, PHOSPHATE ION, ...
Authors:Li, Y, Jin, K, Hao, B.
Deposit date:2017-05-29
Release date:2018-01-17
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural basis of the phosphorylation-independent recognition of cyclin D1 by the SCFFBXO31 ubiquitin ligase.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
2KWQ
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BU of 2kwq by Molmil
Mcm10 C-terminal DNA binding domain
Descriptor: Protein MCM10 homolog, ZINC ION
Authors:Robertson, P.D, Chagot, B, Chazin, W.J, Eichman, B.F.
Deposit date:2010-04-15
Release date:2010-05-19
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Solution NMR structure of the C-terminal DNA binding domain of Mcm10 reveals a conserved MCM motif.
J.Biol.Chem., 285, 2010

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