Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF Ubiquitin Ligase Complex

Summary for 1LDK

Related1LDD 1LDJ
DescriptorCULLIN HOMOLOG, ring-box protein 1, CYCLIN A/CDK2-ASSOCIATED PROTEIN P19, ... (6 entities in total)
Functional Keywordsscf, cullin, rbx1, roc1, hrt1, skp1, skp2, f-box, fbox, ubiquitin, ubiquitination, e3 ligase, ligase
Biological sourceHomo sapiens (human)
Total number of polymer chains5
Total molecular weight118906.87
Primary citation
Zheng, N.,Schulman, B.A.,Song, L.,Miller, J.J.,Jeffrey, P.D.,Wang, P.,Chu, C.,Koepp, D.M.,Elledge, S.J.,Pagano, M.,Conaway, R.C.,Conaway, J.W.,Harper, J.W.,Pavletich, N.P.
Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex.
Nature, 416:703-709, 2002
PubMed: 11961546 (PDB entries with the same primary citation)
DOI: 10.1038/416703a
MImport into Mendeley
Experimental method

Structure validation

ClashscoreRamachandran outliersSidechain outliers85 9.1% 11.5%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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PDB entries from 2020-11-25