6C16

Ubiquitin variant (UbV.Fbl10.1) bound to a human Skp1-Fbl11 fragment complex.

Summary for 6C16

Entry DOI	10.2210/pdb6c16/pdb
Descriptor	S-phase kinase-associated protein 1, Lysine-specific demethylase 2A, Polyubiquitin-B (3 entities in total)
Functional Keywords	ubiquitination, protein binding
Biological source	Homo sapiens (Human) More
Total number of polymer chains	6
Total formula weight	69465.16
Authors	Manczyk, N.,Sicheri, F. (deposition date: 2018-01-04, release date: 2018-07-18, Last modification date: 2023-10-04)
Primary citation	Gorelik, M.,Manczyk, N.,Pavlenco, A.,Kurinov, I.,Sidhu, S.S.,Sicheri, F. A Structure-Based Strategy for Engineering Selective Ubiquitin Variant Inhibitors of Skp1-Cul1-F-Box Ubiquitin Ligases. Structure, 26:1226-, 2018 Cited by PubMed: 30033217 DOI: 10.1016/j.str.2018.06.004 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.27 Å)

Structure validation