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6C16

Ubiquitin variant (UbV.Fbl10.1) bound to a human Skp1-Fbl11 fragment complex.

Functional Information from GO Data
ChainGOidnamespacecontents
A0000082biological_processG1/S transition of mitotic cell cycle
A0000209biological_processprotein polyubiquitination
A0000785cellular_componentchromatin
A0005515molecular_functionprotein binding
A0005634cellular_componentnucleus
A0005654cellular_componentnucleoplasm
A0005737cellular_componentcytoplasm
A0005813cellular_componentcentrosome
A0005829cellular_componentcytosol
A0006338biological_processchromatin remodeling
A0006355biological_processregulation of DNA-templated transcription
A0006511biological_processubiquitin-dependent protein catabolic process
A0006879biological_processintracellular iron ion homeostasis
A0007346biological_processregulation of mitotic cell cycle
A0008013molecular_functionbeta-catenin binding
A0010564biological_processregulation of cell cycle process
A0010824biological_processregulation of centrosome duplication
A0014033biological_processneural crest cell differentiation
A0016567biological_processprotein ubiquitination
A0019005cellular_componentSCF ubiquitin ligase complex
A0019904molecular_functionprotein domain specific binding
A0030510biological_processregulation of BMP signaling pathway
A0031146biological_processSCF-dependent proteasomal ubiquitin-dependent protein catabolic process
A0031467cellular_componentCul7-RING ubiquitin ligase complex
A0031507biological_processheterochromatin formation
A0031519cellular_componentPcG protein complex
A0032006biological_processregulation of TOR signaling
A0042752biological_processregulation of circadian rhythm
A0042981biological_processregulation of apoptotic process
A0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
A0045892biological_processnegative regulation of DNA-templated transcription
A0050727biological_processregulation of inflammatory response
A0051124biological_processsynaptic assembly at neuromuscular junction
A0051298biological_processcentrosome duplication
A0051457biological_processmaintenance of protein location in nucleus
A0051726biological_processregulation of cell cycle
A0060173biological_processlimb development
A0060271biological_processcilium assembly
A0070936biological_processprotein K48-linked ubiquitination
A0097602molecular_functioncullin family protein binding
A0140677molecular_functionmolecular function activator activity
A0160072molecular_functionubiquitin ligase complex scaffold activity
A1901524biological_processregulation of mitophagy
A1904415biological_processregulation of xenophagy
A1990444molecular_functionF-box domain binding
A1990756molecular_functionubiquitin-like ligase-substrate adaptor activity
A1990757molecular_functionubiquitin ligase activator activity
A2000001biological_processregulation of DNA damage checkpoint
B0000082biological_processG1/S transition of mitotic cell cycle
B0000209biological_processprotein polyubiquitination
B0000785cellular_componentchromatin
B0005515molecular_functionprotein binding
B0005634cellular_componentnucleus
B0005654cellular_componentnucleoplasm
B0005737cellular_componentcytoplasm
B0005813cellular_componentcentrosome
B0005829cellular_componentcytosol
B0006338biological_processchromatin remodeling
B0006355biological_processregulation of DNA-templated transcription
B0006511biological_processubiquitin-dependent protein catabolic process
B0006879biological_processintracellular iron ion homeostasis
B0007346biological_processregulation of mitotic cell cycle
B0008013molecular_functionbeta-catenin binding
B0010564biological_processregulation of cell cycle process
B0010824biological_processregulation of centrosome duplication
B0014033biological_processneural crest cell differentiation
B0016567biological_processprotein ubiquitination
B0019005cellular_componentSCF ubiquitin ligase complex
B0019904molecular_functionprotein domain specific binding
B0030510biological_processregulation of BMP signaling pathway
B0031146biological_processSCF-dependent proteasomal ubiquitin-dependent protein catabolic process
B0031467cellular_componentCul7-RING ubiquitin ligase complex
B0031507biological_processheterochromatin formation
B0031519cellular_componentPcG protein complex
B0032006biological_processregulation of TOR signaling
B0042752biological_processregulation of circadian rhythm
B0042981biological_processregulation of apoptotic process
B0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
B0045892biological_processnegative regulation of DNA-templated transcription
B0050727biological_processregulation of inflammatory response
B0051124biological_processsynaptic assembly at neuromuscular junction
B0051298biological_processcentrosome duplication
B0051457biological_processmaintenance of protein location in nucleus
B0051726biological_processregulation of cell cycle
B0060173biological_processlimb development
B0060271biological_processcilium assembly
B0070936biological_processprotein K48-linked ubiquitination
B0097602molecular_functioncullin family protein binding
B0140677molecular_functionmolecular function activator activity
B0160072molecular_functionubiquitin ligase complex scaffold activity
B1901524biological_processregulation of mitophagy
B1904415biological_processregulation of xenophagy
B1990444molecular_functionF-box domain binding
B1990756molecular_functionubiquitin-like ligase-substrate adaptor activity
B1990757molecular_functionubiquitin ligase activator activity
B2000001biological_processregulation of DNA damage checkpoint
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsModified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"21406692","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails

246333

PDB entries from 2025-12-17

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