Three-dimensional structure of human Gadd45alpha in solution by NMR

Summary for 2KG4

DescriptorGrowth arrest and DNA-damage-inducible protein GADD45 alpha (1 entity in total)
Functional Keywordsgadd45, growth arrest, dna damage, flexible regions, monomer, cell cycle
Biological sourceHomo sapiens (human)
Total number of polymer chains1
Total molecular weight18351.72
Sanchez, R.,Pantoja-Uceda, D.,Prieto, J.,Diercks, T.,Campos-Olivas, R.,Blanco, F.J. (deposition date: 2009-03-04, release date: 2009-03-31, Last modification date: 2020-02-26)
Primary citation
Sanchez, R.,Pantoja-Uceda, D.,Prieto, J.,Diercks, T.,Marcaida, M.J.,Montoya, G.,Campos-Olivas, R.,Blanco, F.J.
Solution structure of human growth arrest and DNA damage 45alpha (Gadd45alpha) and its interactions with proliferating cell nuclear antigen (PCNA) and Aurora A kinase
J.Biol.Chem., 285:22196-22201, 2010
PubMed: 20460379 (PDB entries with the same primary citation)
DOI: 10.1074/jbc.M109.069344
MImport into Mendeley
Experimental method
NMR Information

Structure validation

ClashscoreRamachandran outliersSidechain outliers10.5%15.6%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all NMR structures
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