2KG4

Three-dimensional structure of human Gadd45alpha in solution by NMR

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000079	biological_process	regulation of cyclin-dependent protein serine/threonine kinase activity
A	0000122	biological_process	negative regulation of transcription by RNA polymerase II
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0005654	cellular_component	nucleoplasm
A	0005737	cellular_component	cytoplasm
A	0006281	biological_process	DNA repair
A	0006915	biological_process	apoptotic process
A	0006974	biological_process	DNA damage response
A	0007049	biological_process	cell cycle
A	0007098	biological_process	centrosome cycle
A	0016525	biological_process	negative regulation of angiogenesis
A	0016607	cellular_component	nuclear speck
A	0019900	molecular_function	kinase binding
A	0033140	biological_process	negative regulation of peptidyl-serine phosphorylation of STAT protein
A	0042770	biological_process	signal transduction in response to DNA damage
A	0042803	molecular_function	protein homodimerization activity
A	0043065	biological_process	positive regulation of apoptotic process
A	0043537	biological_process	negative regulation of blood vessel endothelial cell migration
A	0046330	biological_process	positive regulation of JNK cascade
A	0046982	molecular_function	protein heterodimerization activity
A	0051726	biological_process	regulation of cell cycle
A	0071260	biological_process	cellular response to mechanical stimulus
A	0071479	biological_process	cellular response to ionizing radiation
A	0071901	biological_process	negative regulation of protein serine/threonine kinase activity
A	1900745	biological_process	positive regulation of p38MAPK cascade
A	1990841	molecular_function	promoter-specific chromatin binding
A	2000379	biological_process	positive regulation of reactive oxygen species metabolic process

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:23186163

Chain	Residue	Details
A	THR2

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