PDB: 9760 resultsInfo pagesStatus searchChemie searchBIRD

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2AJS	Crystal structure of cocaine catalytic antibody 7A1 Fab' in complex with heptaethylene glycol Descriptor: 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, Antibody 7A1 FAB', GLYCEROL, ... Authors: Zhu, X, Wilson, I.A. Deposit date: 2005-08-02 Release date: 2006-02-14 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Complete reaction cycle of a cocaine catalytic antibody at atomic resolution. Structure, 14, 2006
2AJZ	Crystal Structure of Cocaine catalytic Antibody 7A1 Fab' in Complex with ecgonine methyl ester Descriptor: 3-HYDROXY-8-METHYL-8-AZA-BICYCLO[3.2.1]OCTANE-2-CARBOXYLIC ACID METHYL ESTER, Antibody 7A1 Fab' Authors: Zhu, X, Wilson, I.A. Deposit date: 2005-08-02 Release date: 2006-02-14 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Complete reaction cycle of a cocaine catalytic antibody at atomic resolution. Structure, 14, 2006
4Z0X	Structure of Hepatitis C Virus Envelope glycoprotein E2 antigenic region 434-446 bound to the broadly neutralizing antibody HC26AM Descriptor: Antibody HC26AM heavy chain variable domain, Antibody HC26AM light chain variable domain, HCV E2 Antigen (residues 432-446) Authors: Rangarajan, S, Shahid, S, Mariuzza, R.A. Deposit date: 2015-03-26 Release date: 2016-07-20 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2 Å) Cite: Affinity maturation of a broadly neutralizing human monoclonal antibody that prevents acute hepatitis C virus infection in mice. Hepatology, 64, 2016
5UY3	Crystal structure of human Fab PGT144, a broadly reactive and potent HIV-1 neutralizing antibody Descriptor: Antibody PGT144 Fab heavy chain, Antibody PGT144 Fab light chain Authors: Julien, J.-P, Lee, J.H, Wilson, I.A. Deposit date: 2017-02-23 Release date: 2017-04-19 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2.9 Å) Cite: A Broadly Neutralizing Antibody Targets the Dynamic HIV Envelope Trimer Apex via a Long, Rigidified, and Anionic beta-Hairpin Structure. Immunity, 46, 2017
1GPO	CRYSTAL STRUCTURE OF THE RATIONALLY DESIGNED ANTIBODY M41 AS A FAB FRAGMENT Descriptor: ANTIBODY M41, SULFATE ION Authors: Schiweck, W, Skerra, A. Deposit date: 1997-03-27 Release date: 1998-04-01 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.95 Å) Cite: The rational construction of an antibody against cystatin: lessons from the crystal structure of an artificial Fab fragment. J.Mol.Biol., 268, 1997
4K7P	Generation and Characterization of a Unique Reagent that Recognizes a Panel of Recombinant Human Monoclonal Antibody Therapeutics in the Presence of Endogenous Human IgG Descriptor: antibody 10C4 Fab fragment heavy chain, antibody 10C4 Fab fragment light chain, antibody rhumAb6 Fab fragment heavy chain, ... Authors: Eigenbrot, C, Shia, S. Deposit date: 2013-04-17 Release date: 2013-08-07 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.95 Å) Cite: Generation and characterization of a unique reagent that recognizes a panel of recombinant human monoclonal antibody therapeutics in the presence of endogenous human IgG. MAbs, 5, 2013
6L8T	Crystal structure of the Fab fragment of a humanized HBV therapeutic antibody Descriptor: Antibody heavy chain, Antibody light chain Authors: He, M.Z, Gu, Y, Li, S.W. Deposit date: 2019-11-07 Release date: 2020-02-26 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.766 Å) Cite: Structure guided maturation of a novel humanized anti-HBV antibody and its preclinical development. Antiviral Res., 180, 2020
5IIE	STRUCTURE OF THE UNLIGANDED ANTI-HIV ANTIBODY DH501 THAT BINDS GP120 V3 GLYCAN AND THE BASE OF V3 Descriptor: antibody DH501 FabH chain, antibody DH501 light chain Authors: Nicely, N.I, Haynes, B.F. Deposit date: 2016-03-01 Release date: 2017-03-01 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Vaccine Elicitation of High Mannose-Dependent Neutralizing Antibodies against the V3-Glycan Broadly Neutralizing Epitope in Nonhuman Primates. Cell Rep, 18, 2017
1F8T	FAB (LNKB-2) OF MONOCLONAL ANTIBODY, CRYSTAL STRUCTURE Descriptor: ANTIBODY FAB FRAGMENT (HEAVY CHAIN), ANTIBODY FAB FRAGMENT (LIGHT CHAIN) Authors: Fokin, A.V, Afonin, P.V, Mikhailova, I.I, Tsygannik, I.N, Mareeva, T.I. Deposit date: 2000-07-05 Release date: 2001-07-05 Last modified: 2018-04-04 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Spatial structure of a Fab-fragment of a monoclonal antibody to human interleukin-2 in two crystalline forms at a resolution of 2.2 and 2.9 angstroms Bioorg.Khim., 26, 2000
5CEX	Crystal Structure of Fab 32H+109L, a putative precursor of the PGT121 family of potent HIV-1 antibodies Descriptor: Antibody 9H+3L Fab heavy chain, Antibody 9H+3L Fab light chain, GLYCEROL, ... Authors: Garces, F, Wilson, I.A. Deposit date: 2015-07-07 Release date: 2015-12-23 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.105 Å) Cite: Affinity Maturation of a Potent Family of HIV Antibodies Is Primarily Focused on Accommodating or Avoiding Glycans. Immunity, 43, 2015
3OAU	Antibody 2G12 Recognizes Di-Mannose Equivalently in Domain- and Non-Domain-Exchanged Forms, but only binds the HIV-1 Glycan Shield if Domain-Exchanged Descriptor: Fab 2G12, heavy chain, light chain, ... Authors: Doores, K.J, Fulton, Z, Huber, M, Wilson, I.A, Burton, D.R. Deposit date: 2010-08-05 Release date: 2011-01-12 Last modified: 2020-07-29 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Antibody 2G12 recognizes di-mannose equivalently in domain- and nondomain-exchanged forms but only binds the HIV-1 glycan shield if domain exchanged. J.Virol., 84, 2010
5BK5	Crystal structure of the anti-circumsporozoite protein 663 germline antibody Descriptor: 663 germline antibody, heavy chain, light chain, ... Authors: Scally, S.W, Bosch, A, Triller, G, Wardemann, H, Julien, J.P. Deposit date: 2017-09-12 Release date: 2017-12-13 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (3 Å) Cite: Natural Parasite Exposure Induces Protective Human Anti-Malarial Antibodies. Immunity, 47, 2017
5F6I	Crystal Structure of Tier 2 Neutralizing Antibody DH428 from a Rhesus Macaque Descriptor: DH428 Antibody Heavy Chain, DH428 Antibody Light Chain Authors: Fera, D, Harrison, S.C. Deposit date: 2015-12-06 Release date: 2016-01-13 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.32 Å) Cite: Structural Constraints of Vaccine-Induced Tier-2 Autologous HIV Neutralizing Antibodies Targeting the Receptor-Binding Site. Cell Rep, 14, 2016
5BK3	Crystal structure of the neutralizing anti-circumsporozoite protein 580 antibody Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 580 Antibody, heavy chain, ... Authors: Scally, S.W, Bosch, A, Triller, G, Wardemann, H, Julien, J.P. Deposit date: 2017-09-12 Release date: 2017-12-13 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Natural Parasite Exposure Induces Protective Human Anti-Malarial Antibodies. Immunity, 47, 2017
5CHN	Fab fragments of chikungunya virus neutralizing human monoclonal antibody 5M16 Descriptor: Antibody 5M16 Fab Heavy Chain, Antibody 5M16 Fab Light Chain Authors: Long, F, Crowe, J.E, Rossmann, M.G. Deposit date: 2015-07-10 Release date: 2015-11-11 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.047 Å) Cite: Cryo-EM structures elucidate neutralizing mechanisms of anti-chikungunya human monoclonal antibodies with therapeutic activity. Proc.Natl.Acad.Sci.USA, 112, 2015
6KDI	Antibody 64M-5 Fab including isoAsp in complex with dT(6-4)T Descriptor: Anti-(6-4) photoproduct antibody 64M-5 Fab (heavy chain), Anti-(6-4) photoproduct antibody 64M-5 Fab (light chain), DNA (5'-D(*(64T)P*(5PY))-3') Authors: Yokoyama, H, Mizutani, R, Noguchi, S, Hayashida, N. Deposit date: 2019-07-02 Release date: 2019-12-18 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Structural and biochemical basis of the formation of isoaspartate in the complementarity-determining region of antibody 64M-5 Fab. Sci Rep, 9, 2019
6KDH	Antibody 64M-5 Fab including isoAsp in ligand-free form Descriptor: Anti-(6-4) photoproduct antibody 64M-5 Fab (heavy chain), Anti-(6-4) photoproduct antibody 64M-5 Fab (light chain) Authors: Yokoyama, H, Mizutani, R, Noguchi, S, Hayashida, N. Deposit date: 2019-07-02 Release date: 2019-12-18 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.47 Å) Cite: Structural and biochemical basis of the formation of isoaspartate in the complementarity-determining region of antibody 64M-5 Fab. Sci Rep, 9, 2019
5F6H	Crystal Structure of Tier 2 Neutralizing Antibody DH427 from a Rhesus Macaque Descriptor: DH427 Antibody Heavy Chain, DH427 Antibody Light Chain Authors: Fera, D, Harrison, S.C. Deposit date: 2015-12-06 Release date: 2016-01-13 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.66 Å) Cite: Structural Constraints of Vaccine-Induced Tier-2 Autologous HIV Neutralizing Antibodies Targeting the Receptor-Binding Site. Cell Rep, 14, 2016
5F6J	Crystal Structure of Tier 2 Neutralizing Antibody DH427 from a Rhesus Macaque in Complex with HIV-1 gp120 Core Descriptor: DH427 Antibody Heavy Chain, DH427 Antibody Light Chain, ENVELOPE GLYCOPROTEIN GP120 of HIV-1 clade C Authors: Fera, D, Harrison, S.C. Deposit date: 2015-12-06 Release date: 2016-01-13 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (6.63 Å) Cite: Structural Constraints of Vaccine-Induced Tier-2 Autologous HIV Neutralizing Antibodies Targeting the Receptor-Binding Site. Cell Rep, 14, 2016
3HAE	Rational development of high-affinity T-cell receptor-like antibodies Descriptor: Antibody heavy chain, Antibody light chain, Beta-2-microglobulin, ... Authors: Stewart-Jones, G, Wadle, A, Hombach, A, Shenderov, E, Held, G, Fischer, E. Deposit date: 2009-05-01 Release date: 2009-05-19 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Rational development of high-affinity T-cell receptor-like antibodies Proc.Natl.Acad.Sci.USA, 106, 2009
4GXV	Crystal structure of anti-influenza virus antibody 1F1 Descriptor: Antibody 1F1, heavy chain, light chain Authors: Ekiert, D.C, Wilson, I.A. Deposit date: 2012-09-04 Release date: 2012-12-19 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.449 Å) Cite: Influenza Human Monoclonal Antibody 1F1 Interacts with Three Major Antigenic Sites and Residues Mediating Human Receptor Specificity in H1N1 Viruses. Plos Pathog., 8, 2012
1AD0	FAB FRAGMENT OF ENGINEERED HUMAN MONOCLONAL ANTIBODY A5B7 Descriptor: ANTIBODY A5B7 (HEAVY CHAIN), ANTIBODY A5B7 (LIGHT CHAIN) Authors: Banfield, M.J, Brady, R.L. Deposit date: 1997-02-19 Release date: 1998-02-25 Last modified: 2023-08-02 Method: X-RAY DIFFRACTION (2.5 Å) Cite: VL:VH domain rotations in engineered antibodies: crystal structures of the Fab fragments from two murine antitumor antibodies and their engineered human constructs. Proteins, 29, 1997
1H3P	STRUCTURAL CHARACTERISATION OF A MONOCLONAL ANTIBODY SPECIFIC FOR THE PRES1 REGION OF THE HEPATITIS B VIRUS Descriptor: ANTIBODY FAB FRAGMENT Authors: Pizarro, J.C, Vulliez-Le-normand, B, Riottot, M.M, Budkowska, A, Bentley, G.A. Deposit date: 2002-09-12 Release date: 2002-09-19 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Structural and Functional Characterisation of a Monoclonal Antibody Specific for the Pres1 Region of Hepatitis B Virus FEBS Lett., 509, 2001
3GJF	Rational development of high-affinity T-cell receptor-like antibodies Descriptor: Antibody heavy chain, Antibody light chain, Beta-2-microglobulin, ... Authors: Stewart-Jones, G, Wadle, A, Hombach, A, Shenderov, E, Held, G, Fischer, E, Kleber, S, Stenner-Liewen, F, Bauer, S, McMichael, A, Knuth, A, Abken, H, Hombach, A.A, Cerundolo, V, Jones, E.Y, Renner, C. Deposit date: 2009-03-08 Release date: 2009-04-28 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Rational development of high-affinity T-cell receptor-like antibodies Proc.Natl.Acad.Sci.USA, 106, 2009
3G5X	Antibodies Specifically Targeting a Locally Misfolded Region of Tumor Associated EGFR Descriptor: 806 heavy chain, 806 light chain Authors: Garrett, T.P.J, Burgess, A.W. Deposit date: 2009-02-05 Release date: 2009-12-15 Last modified: 2011-10-12 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Antibodies specifically targeting a locally misfolded region of tumor associated EGFR Proc.Natl.Acad.Sci.USA, 106, 2009

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