5IIE

STRUCTURE OF THE UNLIGANDED ANTI-HIV ANTIBODY DH501 THAT BINDS GP120 V3 GLYCAN AND THE BASE OF V3

Summary for 5IIE

Entry DOI	10.2210/pdb5iie/pdb
Descriptor	antibody DH501 FabH chain, antibody DH501 light chain (3 entities in total)
Functional Keywords	hiv-1 antibody gp120, immune system
Biological source	Homo sapiens (Human) More
Total number of polymer chains	4
Total formula weight	94998.17
Authors	Nicely, N.I.,Haynes, B.F. (deposition date: 2016-03-01, release date: 2017-03-01, Last modification date: 2023-09-27)
Primary citation	Saunders, K.O.,Nicely, N.I.,Wiehe, K.,Bonsignori, M.,Meyerhoff, R.R.,Parks, R.,Walkowicz, W.E.,Aussedat, B.,Wu, N.R.,Cai, F.,Vohra, Y.,Park, P.K.,Eaton, A.,Go, E.P.,Sutherland, L.L.,Scearce, R.M.,Barouch, D.H.,Zhang, R.,Von Holle, T.,Overman, R.G.,Anasti, K.,Sanders, R.W.,Moody, M.A.,Kepler, T.B.,Korber, B.,Desaire, H.,Santra, S.,Letvin, N.L.,Nabel, G.J.,Montefiori, D.C.,Tomaras, G.D.,Liao, H.X.,Alam, S.M.,Danishefsky, S.J.,Haynes, B.F. Vaccine Elicitation of High Mannose-Dependent Neutralizing Antibodies against the V3-Glycan Broadly Neutralizing Epitope in Nonhuman Primates. Cell Rep, 18:2175-2188, 2017 Cited by PubMed: 28249163 DOI: 10.1016/j.celrep.2017.02.003 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.8 Å)

Structure validation