6L8T

Crystal structure of the Fab fragment of a humanized HBV therapeutic antibody

Summary for 6L8T

• Entry DOI: 10.2210/pdb6l8t/pdb
• Descriptor: Antibody light chain, Antibody heavy chain (3 entities in total)
• Functional Keywords: antibody, immune system
• Biological source: Homo sapiens; More
• Total number of polymer chains: 6
• Total formula weight: 143178.68

Authors

He, M.Z.,Gu, Y.,Li, S.W. (deposition date: 2019-11-07, release date: 2020-02-26, Last modification date: 2023-11-22)

• Primary citation: Zhou, B.,Xia, L.,Zhang, T.,You, M.,Huang, Y.,He, M.,Su, R.,Tang, J.,Zhang, J.,Li, S.,An, Z.,Yuan, Q.,Luo, W.,Xia, N.; Structure guided maturation of a novel humanized anti-HBV antibody and its preclinical development.; Antiviral Res., 180:104757-104757, 2020; PubMed: 32171857; DOI: 10.1016/j.antiviral.2020.104757

Experimental method

X-RAY DIFFRACTION (1.766 Å)