5BK3

Crystal structure of the neutralizing anti-circumsporozoite protein 580 antibody

Summary for 5BK3

• Entry DOI: 10.2210/pdb5bk3/pdb
• Related: 5BK0 6AZM
• Descriptor: 580 Antibody, light chain, 580 Antibody, heavy chain, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
• Functional Keywords: malaria, circumsporozoite protein, fab, immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 8
• Total formula weight: 198213.82

Authors

Scally, S.W.,Bosch, A.,Triller, G.,Wardemann, H.,Julien, J.P. (deposition date: 2017-09-12, release date: 2017-12-13, Last modification date: 2023-09-27)

• Primary citation: Triller, G.,Scally, S.W.,Costa, G.,Pissarev, M.,Kreschel, C.,Bosch, A.,Marois, E.,Sack, B.K.,Murugan, R.,Salman, A.M.,Janse, C.J.,Khan, S.M.,Kappe, S.H.I.,Adegnika, A.A.,Mordmuller, B.,Levashina, E.A.,Julien, J.P.,Wardemann, H.; Natural Parasite Exposure Induces Protective Human Anti-Malarial Antibodies.; Immunity, 47:1197-1209.e10, 2017; PubMed: 29195810; DOI: 10.1016/j.immuni.2017.11.007

Experimental method

X-RAY DIFFRACTION (2.8 Å)