5CHN
Fab fragments of chikungunya virus neutralizing human monoclonal antibody 5M16
Summary for 5CHN
| Entry DOI | 10.2210/pdb5chn/pdb |
| Descriptor | Antibody 5M16 Fab Heavy Chain, Antibody 5M16 Fab Light Chain (3 entities in total) |
| Functional Keywords | antibody, immune system |
| Biological source | Homo sapiens More |
| Total number of polymer chains | 4 |
| Total formula weight | 94850.12 |
| Authors | Long, F.,Crowe, J.E.,Rossmann, M.G. (deposition date: 2015-07-10, release date: 2015-11-11, Last modification date: 2023-09-27) |
| Primary citation | Long, F.,Fong, R.H.,Austin, S.K.,Chen, Z.,Klose, T.,Fokine, A.,Liu, Y.,Porta, J.,Sapparapu, G.,Akahata, W.,Doranz, B.J.,Crowe, J.E.,Diamond, M.S.,Rossmann, M.G. Cryo-EM structures elucidate neutralizing mechanisms of anti-chikungunya human monoclonal antibodies with therapeutic activity. Proc.Natl.Acad.Sci.USA, 112:13898-13903, 2015 Cited by PubMed: 26504196DOI: 10.1073/pnas.1515558112 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.047 Å) |
Structure validation
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