Loading
PDBj
MenuPDBj@FacebookPDBj@X(formerly Twitter)PDBj@BlueSkyPDBj@YouTubewwPDB FoundationwwPDBDonate
RCSB PDBPDBeBMRBAdv. SearchSearch help

3U3G
DownloadVisualize
BU of 3u3g by Molmil
Structure of LC11-RNase H1 Isolated from Compost by Metagenomic Approach: Insight into the Structural Bases for Unusual Enzymatic Properties of Sto-RNase H1
Descriptor: CHLORIDE ION, Ribonuclease H, UNKNOWN LIGAND
Authors:Nguyen, T.N, Angkawidjaja, C, Kanaya, E, Koga, Y, Takano, K, Kanaya, S.
Deposit date:2011-10-05
Release date:2012-03-07
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Activity, stability, and structure of metagenome-derived LC11-RNase H1, a homolog of Sulfolobus tokodaii RNase H1
Protein Sci., 21, 2012
4Q0B
DownloadVisualize
BU of 4q0b by Molmil
Crystal structure of HIV-1 reverse transcriptase in complex with gap-RNA/DNA and Nevirapine
Descriptor: 11-CYCLOPROPYL-5,11-DIHYDRO-4-METHYL-6H-DIPYRIDO[3,2-B:2',3'-E][1,4]DIAZEPIN-6-ONE, 5'-D(*A*CP*AP*GP*TP*CP*CP*CP*TP*GP*TP*TP*CP*GP*GP*GP*CP*GP*CP*CP*G)-3', 5'-R(*AP*UP*GP*GP*UP*CP*GP*GP*CP*GP*CP*CP*CP*G)-3', ...
Authors:Das, K, Martinez, S.E, Arnold, E.
Deposit date:2014-04-01
Release date:2014-06-18
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structures of HIV-1 RT-RNA/DNA ternary complexes with dATP and nevirapine reveal conformational flexibility of RNA/DNA: insights into requirements for RNase H cleavage.
Nucleic Acids Res., 42, 2014
4PWD
DownloadVisualize
BU of 4pwd by Molmil
Crystal structure of HIV-1 reverse transcriptase in complex with bulge-RNA/DNA and Nevirapine
Descriptor: 11-CYCLOPROPYL-5,11-DIHYDRO-4-METHYL-6H-DIPYRIDO[3,2-B:2',3'-E][1,4]DIAZEPIN-6-ONE, 5'-D(*A*CP*AP*GP*TP*CP*CP*CP*TP*GP*TP*TP*CP*GP*GP*GP*CP*GP*CP*CP*G)-3', 5'-R(*AP*UP*GP*GP*UP*CP*GP*GP*CP*GP*CP*CP*CP*GP*AP*AP*AP*CP*AP*GP*GP*GP*AP*CP*UP*GP*U)-3', ...
Authors:Das, K, Martinez, S.E, Arnold, E.
Deposit date:2014-03-19
Release date:2014-06-18
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structures of HIV-1 RT-RNA/DNA ternary complexes with dATP and nevirapine reveal conformational flexibility of RNA/DNA: insights into requirements for RNase H cleavage.
Nucleic Acids Res., 42, 2014
7WL0
DownloadVisualize
BU of 7wl0 by Molmil
Crystal structure of human ALKBH5 in complex with N-oxalylglycine (NOG) and m6A-containing ssRNA
Descriptor: FORMIC ACID, MANGANESE (II) ION, N-OXALYLGLYCINE, ...
Authors:Kaur, S, McDonough, M.A, Schofield, C.J, Aik, W.S.
Deposit date:2022-01-12
Release date:2022-03-30
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Mechanisms of substrate recognition and N6-methyladenosine demethylation revealed by crystal structures of ALKBH5-RNA complexes.
Nucleic Acids Res., 50, 2022
1FIR
DownloadVisualize
BU of 1fir by Molmil
CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTION PRIMER TRNA(LYS3)
Descriptor: HIV-1 REVERSE TRANSCRIPTION PRIMER TRNA(LYS3), MAGNESIUM ION, SODIUM ION
Authors:Benas, P, Dumas, P.
Deposit date:2000-08-06
Release date:2001-01-17
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:The crystal structure of HIV reverse-transcription primer tRNA(Lys,3) shows a canonical anticodon loop.
RNA, 6, 2000
7V4G
DownloadVisualize
BU of 7v4g by Molmil
Crystal structure of human ALKBH5 in complex with m6A-containing ssRNA
Descriptor: GLYCEROL, MANGANESE (II) ION, RNA (5'-R(P*GP*GP*(6MZ)P*C)-3'), ...
Authors:Kaur, S, McDonough, M.A, Schofield, C.J, Aik, W.S.
Deposit date:2021-08-13
Release date:2022-03-30
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Mechanisms of substrate recognition and N6-methyladenosine demethylation revealed by crystal structures of ALKBH5-RNA complexes.
Nucleic Acids Res., 50, 2022
8H53
DownloadVisualize
BU of 8h53 by Molmil
Human asparaginyl-tRNA synthetase in complex with asparagine-AMP
Descriptor: 4-AMINO-1,4-DIOXOBUTAN-2-AMINIUM ADENOSINE-5'-MONOPHOSPHATE, Asparagine--tRNA ligase, cytoplasmic, ...
Authors:Park, J.S, Han, B.W.
Deposit date:2022-10-12
Release date:2023-10-25
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.16 Å)
Cite:Reaction hijacking inhibition of Plasmodium falciparum asparagine tRNA synthetase.
Nat Commun, 15, 2024
7WKV
DownloadVisualize
BU of 7wkv by Molmil
Crystal structure of human ALKBH5 in complex with 2-oxoglutarate (2OG) and m6A-containing ssRNA
Descriptor: 2-OXOGLUTARIC ACID, MANGANESE (II) ION, RNA (5'-R(P*GP*GP*(6MZ)P*C)-3'), ...
Authors:Kaur, S, McDonough, M.A, Schofield, C.J, Aik, W.S.
Deposit date:2022-01-11
Release date:2022-03-30
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Mechanisms of substrate recognition and N6-methyladenosine demethylation revealed by crystal structures of ALKBH5-RNA complexes.
Nucleic Acids Res., 50, 2022
3J5S
DownloadVisualize
BU of 3j5s by Molmil
EttA binds to ribosome exit site and regulates translation by restricting ribosome and tRNA dynamics
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S7, ...
Authors:Hashem, Y.
Deposit date:2013-11-15
Release date:2014-01-08
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (7.5 Å)
Cite:EttA regulates translation by binding the ribosomal E site and restricting ribosome-tRNA dynamics.
Nat.Struct.Mol.Biol., 21, 2014
1MMS
DownloadVisualize
BU of 1mms by Molmil
Crystal structure of the ribosomal PROTEIN L11-RNA complex
Descriptor: 23S RIBOSOMAL RNA, CADMIUM ION, MAGNESIUM ION, ...
Authors:Wimberly, B.T, Guymon, R, Mccutcheon, J.P, White, S.W, Ramakrishnan, V.
Deposit date:1999-04-14
Release date:2000-04-17
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.57 Å)
Cite:A detailed view of a ribosomal active site: the structure of the L11-RNA complex.
Cell(Cambridge,Mass.), 97, 1999
4WLS
DownloadVisualize
BU of 4wls by Molmil
Crystal structure of the metal-free (repressor) form of E. Coli CUER, a copper efflux regulator, bound to COPA promoter DNA
Descriptor: COPA PROMOTER DNA NON-TEMPLATE STRAND, COPA PROMOTER DNA NON-TEMPLATE STRAND (ALTERNATE CONFORMATION), COPA PROMOTER DNA TEMPLATE STRAND, ...
Authors:Philips, S.J, Canalizo-Hernandez, M, Mondragon, A, O'Halloran, T.V.
Deposit date:2014-10-08
Release date:2015-09-02
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.105 Å)
Cite:Allosteric transcriptional regulation via changes in the overall topology of the core promoter.
Science, 349, 2015
3WQY
DownloadVisualize
BU of 3wqy by Molmil
Crystal structure of Archaeoglobus fulgidus alanyl-tRNA synthetase in complex with wild-type tRNA(Ala) having G3.U70
Descriptor: '5'-O-(N-(L-ALANYL)-SULFAMOYL)ADENOSINE, Alanine--tRNA ligase, MAGNESIUM ION, ...
Authors:Naganuma, M, Sekine, S, Yokoyama, S.
Deposit date:2014-02-05
Release date:2014-06-18
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:The selective tRNA aminoacylation mechanism based on a single G.U pair
Nature, 510, 2014
3WQZ
DownloadVisualize
BU of 3wqz by Molmil
Crystal structure of Archaeoglobus fulgidus alanyl-tRNA synthetase in complex with a tRNA(Ala) variant having A3.U70
Descriptor: '5'-O-(N-(L-ALANYL)-SULFAMOYL)ADENOSINE, Alanine--tRNA ligase, RNA (75-MER), ...
Authors:Naganuma, M, Sekine, S, Yokoyama, S.
Deposit date:2014-02-05
Release date:2014-06-18
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (3.489 Å)
Cite:The selective tRNA aminoacylation mechanism based on a single G.U pair
Nature, 510, 2014
4LWQ
DownloadVisualize
BU of 4lwq by Molmil
Crystal structure of native peptidyl t-RNA hydrolase from Acinetobacter baumannii at 1.38A resolution
Descriptor: GLYCEROL, Peptidyl-tRNA hydrolase
Authors:Kaushik, S, Singh, N, Sinha, M, Kaur, P, Sharma, S, Singh, T.P.
Deposit date:2013-07-28
Release date:2013-08-14
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.38 Å)
Cite:Crystal structure of native peptidyl t-RNA hydrolase from Acinetobacter baumannii at 1.38A resolution
To be Published
7Q4L
DownloadVisualize
BU of 7q4l by Molmil
The solution structure of hsDND1 RRM12 bound to CUUAUUUG RNA
Descriptor: Dead end protein homolog 1, RNA (5'-R(*CP*UP*UP*AP*UP*UP*UP*G)-3')
Authors:Duszczyk, M.M, Allain, F.H.T.
Deposit date:2021-10-31
Release date:2022-05-04
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:The solution structure of Dead End bound to AU-rich RNA reveals an unusual mode of tandem RRM-RNA recognition required for mRNA regulation.
Nat Commun, 13, 2022
8R8R
DownloadVisualize
BU of 8r8r by Molmil
Cryo-EM structure of the human mPSF with PAPOA C-terminus peptide (PAPOAc)
Descriptor: Cleavage and polyadenylation specificity factor subunit 1, Cleavage and polyadenylation specificity factor subunit 4, RNA (5'-R(P*AP*AP*UP*AP*AP*A)-3'), ...
Authors:Todesca, S, Sandmeir, F, Keidel, A, Conti, E.
Deposit date:2023-11-29
Release date:2024-04-10
Last modified:2025-07-02
Method:ELECTRON MICROSCOPY (2.79 Å)
Cite:Molecular basis of human poly(A) polymerase recruitment by mPSF.
Rna, 30, 2024
7DPI
DownloadVisualize
BU of 7dpi by Molmil
Plasmodium falciparum cytoplasmic Phenylalanyl-tRNA synthetase in complex with BRD7929
Descriptor: (8R,9S,10S)-10-[(dimethylamino)methyl]-N-(4-methoxyphenyl)-9-[4-(2-phenylethynyl)phenyl]-1,6-diazabicyclo[6.2.0]decane-6-carboxamide, MAGNESIUM ION, Phenylalanine--tRNA ligase, ...
Authors:Manmohan, S, Malhotra, N, Harlos, K, Manickam, Y, Sharma, A.
Deposit date:2020-12-19
Release date:2022-03-23
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (3.597 Å)
Cite:Inhibition of Plasmodium falciparum phenylalanine tRNA synthetase provides opportunity for antimalarial drug development.
Structure, 30, 2022
7TZB
DownloadVisualize
BU of 7tzb by Molmil
Crystal structure of the human mitochondrial seryl-tRNA synthetase (mt SerRS) bound with a seryl-adenylate analogue
Descriptor: 5'-O-(N-(L-SERYL)-SULFAMOYL)ADENOSINE, Serine--tRNA ligase, mitochondrial
Authors:Kuhle, B, Hirschi, M, Doerfel, L, Lander, G, Schimmel, P.
Deposit date:2022-02-15
Release date:2022-09-14
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Structural basis for shape-selective recognition and aminoacylation of a D-armless human mitochondrial tRNA.
Nat Commun, 13, 2022
7E44
DownloadVisualize
BU of 7e44 by Molmil
Crystal structure of NudC complexed with dpCoA
Descriptor: DEPHOSPHO COENZYME A, NADH pyrophosphatase, ZINC ION
Authors:Zhou, W, Guan, Z.Y, Yin, P, Zhang, D.L.
Deposit date:2021-02-10
Release date:2021-07-28
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural insights into dpCoA-RNA decapping by NudC.
Rna Biol., 18, 2021
7ULZ
DownloadVisualize
BU of 7ulz by Molmil
Crystal Structure of Methionine-tRNA ligase / Methionyl-tRNA synthetase (MetRS) from Pseudomonas aeruginosa PAO1
Descriptor: METHIONINE, Methionine--tRNA ligase, SULFATE ION
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2022-04-05
Release date:2022-04-27
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal Structure of Methionine-tRNA ligase / Methionyl-tRNA synthetase (MetRS) from Pseudomonas aeruginosa PAO1
to be published
5AH5
DownloadVisualize
BU of 5ah5 by Molmil
Crystal structure of the ternary complex of Agrobacterium radiobacter K84 agnB2 LeuRS-tRNA-LeuAMS
Descriptor: 5'-O-(L-leucylsulfamoyl)adenosine, LEUCINE--TRNA LIGASE, MANGANESE (II) ION, ...
Authors:Palencia, A, Chopra, S, Virus, C, Schulwitz, S, Temple, B.R, Cusack, S, Reader, J.S.
Deposit date:2015-02-05
Release date:2016-02-17
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural Characterization of Antibiotic Self-Immunity tRNA Synthetase in Plant Tumour Biocontrol Agent.
Nat.Commun., 7, 2016
2BH2
DownloadVisualize
BU of 2bh2 by Molmil
Crystal Structure of E. coli 5-methyluridine methyltransferase RumA in complex with ribosomal RNA substrate and S-adenosylhomocysteine.
Descriptor: 23S RIBOSOMAL RNA 1932-1968, 23S RRNA (URACIL-5-)-METHYLTRANSFERASE RUMA, IRON/SULFUR CLUSTER, ...
Authors:Lee, T.T, Agarwalla, S, Stroud, R.M.
Deposit date:2005-01-06
Release date:2005-03-30
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:A Unique RNA Fold in the Ruma-RNA-Cofactor Ternary Complex Contributes to Substrate Selectivity and Enzymatic Function
Cell(Cambridge,Mass.), 120, 2005
8Y04
DownloadVisualize
BU of 8y04 by Molmil
Crystal structure of LbCas12a in complex with crRNA and 6nt target DNA
Descriptor: DNA (5'-D(*CP*GP*TP*CP*CP*TP*TP*TP*AP*TP*T)-3'), DNA (5'-D(P*GP*AP*TP*GP*CP*GP*TP*AP*AP*AP*GP*GP*AP*CP*G)-3'), LbCas12a, ...
Authors:Lin, X, Chen, J, Liu, L.
Deposit date:2024-01-22
Release date:2025-01-01
Last modified:2025-02-19
Method:X-RAY DIFFRACTION (3.71 Å)
Cite:DNA target binding-induced pre-crRNA processing in type II and V CRISPR-Cas systems.
Nucleic Acids Res., 53, 2025
8Y0A
DownloadVisualize
BU of 8y0a by Molmil
Crystal structure of LbCas12a in complex with crRNA and 18nt target DNA
Descriptor: DNA (27-MER), DNA (5'-D(*CP*GP*TP*CP*CP*TP*TP*TP*AP*TP*T)-3'), LbCas12a, ...
Authors:Lin, X, Chen, J, Liu, L.
Deposit date:2024-01-22
Release date:2025-01-01
Last modified:2025-02-19
Method:X-RAY DIFFRACTION (3.51 Å)
Cite:DNA target binding-induced pre-crRNA processing in type II and V CRISPR-Cas systems.
Nucleic Acids Res., 53, 2025
8Y06
DownloadVisualize
BU of 8y06 by Molmil
Crystal structure of LbCas12a in complex with crRNA and 12nt target DNA
Descriptor: DNA (5'-D(*CP*GP*TP*CP*CP*TP*TP*TP*AP*TP*T)-3'), DNA (5'-D(P*TP*TP*AP*CP*TP*GP*GP*AP*TP*GP*CP*GP*TP*AP*AP*AP*GP*GP*AP*CP*G)-3'), LbCas12a, ...
Authors:Lin, X, Chen, J, Liu, L.
Deposit date:2024-01-22
Release date:2025-01-01
Last modified:2025-02-19
Method:X-RAY DIFFRACTION (3.99 Å)
Cite:DNA target binding-induced pre-crRNA processing in type II and V CRISPR-Cas systems.
Nucleic Acids Res., 53, 2025

238582

건을2025-07-09부터공개중

PDB statisticsPDBj update infoContact PDBjnumon