2BH2

Crystal Structure of E. coli 5-methyluridine methyltransferase RumA in complex with ribosomal RNA substrate and S-adenosylhomocysteine.

Summary for 2BH2

Entry DOI	10.2210/pdb2bh2/pdb
Related	1UWV
Descriptor	23S RRNA (URACIL-5-)-METHYLTRANSFERASE RUMA, 23S RIBOSOMAL RNA 1932-1968, S-ADENOSYL-L-HOMOCYSTEINE, ... (5 entities in total)
Functional Keywords	iron-sulfur cluster, methyltransferase, rna modification, rna processing, transferase, ruma, base flipping, sam, ob-fold, protein-rna complex, base stacking, substrate selectivity, general base, product release, 4fe-4s, metal-binding
Biological source	ESCHERICHIA COLI More
Total number of polymer chains	4
Total formula weight	121464.56
Authors	Lee, T.T.,Agarwalla, S.,Stroud, R.M. (deposition date: 2005-01-06, release date: 2005-03-30, Last modification date: 2023-12-13)
Primary citation	Lee, T.T.,Agarwalla, S.,Stroud, R.M. A Unique RNA Fold in the Ruma-RNA-Cofactor Ternary Complex Contributes to Substrate Selectivity and Enzymatic Function Cell(Cambridge,Mass.), 120:599-, 2005 Cited by PubMed: 15766524 DOI: 10.1016/J.CELL.2004.12.037 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.15 Å)

Structure validation