6FCE
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![BU of 6fce by Molmil](/molmil-images/mine/6fce) | NMR ensemble of Macrocyclic Peptidomimetic Containing Constrained a,a-dialkylated Amino Acids with Potent and Selective Activity at Human Melanocortin Receptors | Descriptor: | ACP-HIS-DPHE-ARG-TRP-ASP-NH2 | Authors: | Brancaccio, D, Carotenuto, A, Grieco, P, Merlino, F, Zhou, Y, Cai, M, Yousif, A.M, Di Maro, S, Novellino, E, Hruby, V.J. | Deposit date: | 2017-12-20 | Release date: | 2018-04-25 | Last modified: | 2018-05-23 | Method: | SOLUTION NMR | Cite: | Development of Macrocyclic Peptidomimetics Containing Constrained alpha , alpha-Dialkylated Amino Acids with Potent and Selective Activity at Human Melanocortin Receptors. J. Med. Chem., 61, 2018
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5MXS
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5MMK
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![BU of 5mmk by Molmil](/molmil-images/mine/5mmk) | HYL-20 | Descriptor: | GLY-ILE-LEU-SER-SER-LEU-TRP-LYS-LYS-LEU-LYS-LYS-ILE-ILE-ALA-LYS | Authors: | Hexnerova, R. | Deposit date: | 2016-12-10 | Release date: | 2017-09-06 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | How proteases from Enterococcus faecalis contribute to its resistance to short alpha-helical antimicrobial peptides. Pathog Dis, 75, 2017
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5MML
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![BU of 5mml by Molmil](/molmil-images/mine/5mml) | HYL-20k | Descriptor: | GLY-ILE-LEU-SER-SER-LEU-TRP-LYS-LYS-LEU-LYS-LYS-ILE-ILE-ALA-LYS | Authors: | Hexnerova, R. | Deposit date: | 2016-12-10 | Release date: | 2017-09-06 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | How proteases from Enterococcus faecalis contribute to its resistance to short alpha-helical antimicrobial peptides. Pathog Dis, 75, 2017
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5MXT
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5ZYX
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![BU of 5zyx by Molmil](/molmil-images/mine/5zyx) | Solution NMR structure of K30 peptide in 10 mM dioctanoyl phosphatidylglycerol (D8PG) | Descriptor: | ARG-TRP-LYS-ARG-HIS-ILE-SER-GLU-GLN-LEU-ARG-ARG-ARG-ASP-ARG-LEU-GLN-ARG-GLN-ALA | Authors: | Bhunia, A, Mohid, A, Stella, L, Calligari, P. | Deposit date: | 2018-05-28 | Release date: | 2019-06-12 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Design, Synthesis, Antibacterial Potential, and Structural Characterization of N-Acylated Derivatives of the Human Autophagy 16 Polypeptide. Bioconjug.Chem., 30, 2019
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6M0Y
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![BU of 6m0y by Molmil](/molmil-images/mine/6m0y) | KR-12 analog derived from human LL-37 | Descriptor: | LYS-ARG-ILE-VAL-LYS-ARG-ILE-LYS-LYS-TRP-LEU-ARG | Authors: | Yun, H, Min, H.J, Lee, C.W. | Deposit date: | 2020-02-24 | Release date: | 2021-02-24 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | NMR Structure and Bactericidal Activity of KR-12 Analog Derived from Human LL-37 as a Potential Cosmetic Preservative To Be Published
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6S0N
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![BU of 6s0n by Molmil](/molmil-images/mine/6s0n) | A9 peptide derived from Herceptin fab binding region | Descriptor: | GLN-ASP-VAL-ASN-THR-ALA-VAL-ALA-TRP | Authors: | De Luca, S, Verdoliva, V, Saviano, M, Fattorusso, R, Diana, D. | Deposit date: | 2019-06-17 | Release date: | 2019-11-06 | Last modified: | 2024-06-19 | Method: | SOLUTION NMR | Cite: | SPR and NMR characterization of the molecular interaction between A9 peptide and a model system of HER2 receptor: A fragment approach for selecting peptide structures specific for their target. J.Pept.Sci., 26, 2020
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6OQP
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![BU of 6oqp by Molmil](/molmil-images/mine/6oqp) | U-AITx-Ate1 | Descriptor: | SER-LYS-TRP-ILE-CYS-ALA-ASN-ARG-SER-VAL-CYS-PRO-ILE | Authors: | Elnahriry, K.A, Wai, D.C.C, Norton, R.S. | Deposit date: | 2019-04-28 | Release date: | 2019-07-31 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Structural and functional characterisation of a novel peptide from the Australian sea anemone Actinia tenebrosa. Toxicon, 168, 2019
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6QXB
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![BU of 6qxb by Molmil](/molmil-images/mine/6qxb) | NMR structure of peptide 7, characterized by a cis-4-amino-Pro residue, with a significant lower MIC on E. coli | Descriptor: | PHE-VAL-CAP-TRP-PHE-SER-LYS-PHE-LEU-GLY-ARG-ILE-LEU-NH2 | Authors: | Brancaccio, D, Carotenuto, A, Merlino, F, Grieco, P, Novellino, E. | Deposit date: | 2019-03-07 | Release date: | 2019-05-29 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | The Outcomes of Decorated Prolines in the Discovery of Antimicrobial Peptides from Temporin-L. Chemmedchem, 14, 2019
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6QXC
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![BU of 6qxc by Molmil](/molmil-images/mine/6qxc) | NMR structure of peptide 8, characterized by a trans-4-cyclohexyl-Pro, with a dramatic reduction in activity on E. coli ATCC and lost effect on P. aeruginosa. | Descriptor: | PHE-VAL-TCP-TRP-PHE-SER-LYS-PHE-LEU-GLY-ARG-ILE-LEU-NH2 | Authors: | Brancaccio, D, Carotenuto, A, Merlino, F, Grieco, P, Novellino, E. | Deposit date: | 2019-03-07 | Release date: | 2019-05-29 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | The Outcomes of Decorated Prolines in the Discovery of Antimicrobial Peptides from Temporin-L. Chemmedchem, 14, 2019
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6BJF
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![BU of 6bjf by Molmil](/molmil-images/mine/6bjf) | NMR Structural and biophysical functional analysis of intracellular loop 5 of the NHE1 isoform of the Na+/H+ exchanger. | Descriptor: | GLY-LEU-THR-TRP-PHE-ILE-ASN-LYS-PHE-ARG-ILE-VAL-LYS | Authors: | McKay, R, Wong, K, Towle, K, Fliegel, L. | Deposit date: | 2017-11-06 | Release date: | 2018-11-14 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Diverse residues of intracellular loop 5 of the Na+/H+exchanger modulate proton sensing, expression, activity and targeting. Biochim Biophys Acta Biomembr, 1861, 2019
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8QAQ
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![BU of 8qaq by Molmil](/molmil-images/mine/8qaq) | Conformations of macrocyclic peptides sampled by exact NOEs: models for cell-permeability. Conformation 1 of omphalotin A in apolar solvents. | Descriptor: | TRP-MVA-ILE-MVA-MVA-SAR-MVA-IML-SAR-VAL-IML-SAR | Authors: | Ruedisser, S.H, Matabaro, E, Sonderegger, L, Guentert, P, Kuenzler, M, Gossert, A.D. | Deposit date: | 2023-08-23 | Release date: | 2023-12-06 | Last modified: | 2024-01-03 | Method: | SOLUTION NMR | Cite: | Conformations of Macrocyclic Peptides Sampled by Nuclear Magnetic Resonance: Models for Cell-Permeability. J.Am.Chem.Soc., 145, 2023
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8QAS
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![BU of 8qas by Molmil](/molmil-images/mine/8qas) | Conformations of macrocyclic peptides sampled by exact NOEs: models for cell-permeability. NMR structure of Omphalotin A in methanol / water indoleOut conformation. | Descriptor: | TRP-MVA-ILE-MVA-MVA-SAR-MVA-IML-SAR-VAL-IML-SAR | Authors: | Ruedisser, S.H, Matabaro, E, Sonderegger, L, Guentert, P, Kuenzler, M, Gossert, A.D. | Deposit date: | 2023-08-23 | Release date: | 2023-12-06 | Last modified: | 2024-01-03 | Method: | SOLUTION NMR | Cite: | Conformations of Macrocyclic Peptides Sampled by Nuclear Magnetic Resonance: Models for Cell-Permeability. J.Am.Chem.Soc., 145, 2023
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8QBP
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![BU of 8qbp by Molmil](/molmil-images/mine/8qbp) | Conformations of macrocyclic peptides sampled by exact NOEs: models for cell-permeability. NMR structure of Omphalotin A in methanol / water indoleOut conformation. | Descriptor: | TRP-MVA-ILE-MVA-MVA-SAR-MVA-IML-SAR-VAL-IML-SAR | Authors: | Ruedisser, S.H, Matabaro, E, Sonderegger, L, Guentert, P, Kuenzler, M, Gossert, A.D. | Deposit date: | 2023-08-25 | Release date: | 2023-12-13 | Last modified: | 2024-01-03 | Method: | SOLUTION NMR | Cite: | Conformations of Macrocyclic Peptides Sampled by Nuclear Magnetic Resonance: Models for Cell-Permeability. J.Am.Chem.Soc., 145, 2023
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7V5E
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7TRP
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![BU of 7trp by Molmil](/molmil-images/mine/7trp) | Human M4 muscarinic acetylcholine receptor complex with Gi1 and the agonist iperoxo and positive allosteric modulator LY2033298 | Descriptor: | 3-amino-5-chloro-N-cyclopropyl-6-methoxy-4-methylthieno[2,3-b]pyridine-2-carboxamide, 4-(4,5-dihydro-1,2-oxazol-3-yloxy)-N,N,N-trimethylbut-2-yn-1-aminium, Antibody fragment scFv16, ... | Authors: | Vuckovic, Z, Mobbs, J.I, Belousoff, M.J, Glukhova, A, Sexton, P.M, Danev, R, Thal, D.M. | Deposit date: | 2022-01-30 | Release date: | 2023-05-17 | Method: | ELECTRON MICROSCOPY (2.4 Å) | Cite: | Structural and dynamic mechanisms of allostery at the M4 muscarinic acetylcholine receptor Elife, 2023
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4TRP
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![BU of 4trp by Molmil](/molmil-images/mine/4trp) | Crystal structure of monoclonal antibody against neuroblastoma associated antigen. | Descriptor: | Heavy chain of monoclonal antibody against neuroblastoma associated antigen, Light chain of monoclonal antibody against neuroblastoma associated antigen | Authors: | Horwacik, I, Golik, P, Grudnik, P, Zdzalik, M, Rokita, H, Dubin, G. | Deposit date: | 2014-06-17 | Release date: | 2015-07-15 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.25 Å) | Cite: | Structural Basis of GD2 Ganglioside and Mimetic Peptide Recognition by 14G2a Antibody. Mol.Cell Proteomics, 14, 2015
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6TRP
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![BU of 6trp by Molmil](/molmil-images/mine/6trp) | Solution Structure of Docking Domain Complex of Pax NRPS: PaxC NDD - PaxB CDD | Descriptor: | Peptide synthetase XpsB,Peptide synthetase XpsB | Authors: | Watzel, J, Hacker, C, Duchardt-Ferner, E, Bode, H.B, Woehnert, J. | Deposit date: | 2019-12-19 | Release date: | 2020-08-12 | Last modified: | 2024-06-19 | Method: | SOLUTION NMR | Cite: | A New Docking Domain Type in the Peptide-Antimicrobial-Xenorhabdus Peptide Producing Nonribosomal Peptide Synthetase fromXenorhabdus bovienii. Acs Chem.Biol., 15, 2020
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5TRP
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3TRP
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![BU of 3trp by Molmil](/molmil-images/mine/3trp) | Crystal structure of recombinant rabbit skeletal calsequestrin | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, ... | Authors: | Sanchez, E.J, Lewis, K.M, Munske, G.R, Nissen, M.S, Kang, C. | Deposit date: | 2011-09-09 | Release date: | 2012-02-22 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.8817 Å) | Cite: | High-capacity Ca2+ Binding of Human Skeletal Calsequestrin. J.Biol.Chem., 287, 2012
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8TRP
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3TRQ
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![BU of 3trq by Molmil](/molmil-images/mine/3trq) | Crystal structure of native rabbit skeletal calsequestrin | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, ... | Authors: | Sanchez, E.J, Lewis, K.M, Munske, G.R, Nissen, M.S, Kang, C. | Deposit date: | 2011-09-09 | Release date: | 2011-12-21 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.76 Å) | Cite: | Glycosylation of Skeletal Calsequestrin: IMPLICATIONS FOR ITS FUNCTION. J.Biol.Chem., 287, 2012
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8ZJE
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![BU of 8zje by Molmil](/molmil-images/mine/8zje) | Cryo-EM structure of kisspeptin receptor bound to TAK-448 | Descriptor: | ACY-DTY-HYP-ASN-THR-PHE-XZA-LEU-NMM-TRP-NH2, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Shen, S, Liu, H, Xu, H.E. | Deposit date: | 2024-05-14 | Release date: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3.07 Å) | Cite: | Cryo-EM structure of kisspeptin receptor bound to TAK-448 To Be Published
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5X54
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![BU of 5x54 by Molmil](/molmil-images/mine/5x54) | Crystal structure of the Keap1 Kelch domain in complex with a tetrapeptide | Descriptor: | ACE-GLU-TRP-TRP-TRP, ACETATE ION, Kelch-like ECH-associated protein 1 | Authors: | Sogabe, S, Kadotani, A, Lane, W, Snell, G. | Deposit date: | 2017-02-14 | Release date: | 2017-03-29 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Discovery of a Kelch-like ECH-associated protein 1-inhibitory tetrapeptide and its structural characterization Biochem. Biophys. Res. Commun., 486, 2017
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