1T8O

CRYSTAL STRUCTURE OF THE P1 TRP BPTI MUTANT- BOVINE CHYMOTRYPSIN COMPLEX

Summary for 1T8O

Entry DOI	10.2210/pdb1t8o/pdb
Related	1CBW 1MTN 1P2M 1P2N 1P2O 1P2Q 1T7C 1T8L 1T8M 1T8N
Descriptor	Chymotrypsin A, Pancreatic trypsin inhibitor, SULFATE ION, ... (4 entities in total)
Functional Keywords	chymotrypsin, serine proteinase, bovine pancreatic trypsin inhibitor, bpti, protein-protein interaction, non-cognate binding, s1 pocket, primary specificity, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	Bos taurus (cattle) More
Cellular location	Secreted, extracellular space: P00766 Secreted: P00974
Total number of polymer chains	4
Total formula weight	65465.82
Authors	Czapinska, H.,Helland, R.,Otlewski, J.,Smalas, A.O. (deposition date: 2004-05-13, release date: 2005-03-08, Last modification date: 2023-08-23)
Primary citation	Czapinska, H.,Helland, R.,Smalas, A.O.,Otlewski, J. Crystal structures of five bovine chymotrypsin complexes with P1 BPTI variants. J.Mol.Biol., 344:1005-1020, 2004 Cited by PubMed: 15544809 DOI: 10.1016/j.jmb.2004.09.088 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.7 Å)

Structure validation